[PDF] Top 20 Abnormal expression of GADD45B in human colorectal carcinoma

... In human solid tumors, DNA damage and repair defects that lead to tumorigenesis usually involve mul- tiple ...of GADD45B expression influence apoptosis-related proteins ...that GADD45B-induced ... See full document

... are abnormal expression in tumor samples, which includes many immune factors, likes CD3D, DCLRE1C, IL7R, BTK and CD3E which are involved in primary ... See full document

... Immunohistochemical staining Tumor tissues and normal tissues were fixed in 10% formaldehyde and were paraffin wax-embedded. Subse- quently, the tissues were cut into 5-μm-thick serial sec- tions, which were washed ... See full document

... 38 resected CRC samples and paired non-cancerous tis- sues were obtained from the patients of Huashan hospi- tal, Shanghai, China, undergone radical surgery for colorectal cancer (20 males and 18 females). All ... See full document

... Introduction Colorectal carcinoma is the third most common type of fatal malignancy in the People’s Republic of China and is the second highest cause of cancer-related death ...of colorectal ... See full document

... FLEX Monoclonal Mouse Anti – Human beta catenin,clone betacatenin -1, Ready to use is used in this study.The catenin’s are structurally related cy- toplasmic proteins which have been classified as alpha,beta,gamma ... See full document

... Cytoplasmic positivity was infrequently encountered and was considered as an artifact. Tumors were graded according to the percentage of positive cells and were scored quantitatively according to the 3-tiered system as ... See full document

... Fuchs and Bode, 2005; Kaira et al., 2009; Fan et al., 2010). However, the differences in amino acid transporter expression among different carcinoma histologic subtypes have not been fully examined. We ... See full document

... In normal colon the proliferative compartment is located at the base of the crypts, whereas in adenoma there is an upward shift of proliferative compartment which cause dysregulation evidenced by use of proliferative ... See full document

... HCT-116 human colon cancer cells resulted in enhanced β-catenin expression that was reversed by addition of human recombinant ...LGALS3BP expression in tumor tissue associated with clinical ... See full document

... the human colon cancer cells in logarithm growth phrase were harvested and washed twice with ...mRNA expression of the related genes and the other was used for immunohistochemical analy- sis as described ... See full document

... in human colorectal cancers into statistically significant groups, we applied a parametric cluster analysis based on the Gaussian mixture model [15-17] and Bayes ...of expression data to the Gaussian ... See full document

... IHC is performed in formalin fixed paraffin embedded tissue blocks. The results were interpreted HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER-2 / neu) HER-2 is also known as proto-oncogene Neu. The oncogene neu ... See full document

... in colorectal cancer. In this study, we investigated MAGED1 expression and its clinical signifi- cance in human colorectal ...MAGED1 expression was significantly down-regulated in ... See full document

... the human embryonic kidney cell line HEK-293 and osteoblastic cell line HOS-TE85, resulting in lower OPG mRNA than in the primary human osteoblastic cell lines hOB and MG- 63, both of which have higher OPG ... See full document

... Bcl-xL expression only showed statistical difference in CT ...high- expression and low-expression protein ...lower expression of Bcl-xL in either CT or NM regions were associated with better ... See full document

... Over these years, CAPS, initially identified as a major phosphorylated substrate for cAMP-dependent protein kinase A after stimulation of thyroid cells by thyrotropin, has been put into deeper research. 7 Some ... See full document

... P53 protein is constitutively expressed in most normal tissues. The normal cell has a very low quantity of the wild type protein because of it’s short half-life of about 6-20 minutes 9 . Thus, it is not detectable by ... See full document

... The adjacent tissues were collected 3‑5 cm away from the tumor edge; they may have included adenoma tissue adjacent to the carcinoma rather than heterogeneous samples composed of mucosa, muscularis and serosa. The ... See full document

... nasopharyngeal carcinoma, osteosar- coma, and other human malignancies in tumor- igenesis and development ...positive expression rate of ...PIK3CB expression is associated with cell dif- ... See full document