[PDF] Top 20 The accuracy of presepsin (sCD14 ST) for the diagnosis of sepsis in adults: a meta analysis

... diagnostic accuracy of presepsin for ...of sepsis varied from 16.4 % to 79.2 %. The most frequent source of sepsis was pulmonary in- ...ence presepsin levels. Presepsin levels ... See full document

... the diagnosis of neonatal and paediatric sepsis, larger, high quality studies are ...Diagnostic Accuracy (STARD) guide- lines, with a previously published and registered protocol, and an adequate ... See full document

... the diagnosis of neonatal sepsis. In addition, this meta-analysis shows that presepsin may be used alone to diagnose and rule out neonatal sepsis due to its high sensitivity and ... See full document

... in sepsis. The generation and release of the presepsin are cleaved from the monocyte/macrophage-speci fi c CD14 receptor complex which is binding with bacterial lipopo- lysaccharide (LPS) and LPS binding ... See full document

... Then, sCD14 is activated by plasma proteases during the circulating process, and thus generates a 13 kDa protein named sCD14-ST or ...presepsin. Presepsin increases signifi- cantly in ... See full document

... generates presepsin (13, 14). Presepsin is a 13-kDa protein, a truncated N-terminal fragment of CD14 ...of presepsin are related to the phagocytosis process and cleavage of membrane CD14 with ... See full document

... called presepsin is released into the circulation from the surface of membranes of immune cells and also actively secreted from these tissues [9, ...of presepsin in blood circulation are thought to reflect ... See full document

... The diagnosis of sepsis remains a clinical ...that presepsin plays a role in diagnosing sepsis, but the results remain ...diagnostic accuracy of presepsin for sepsis ... See full document

... OR presepsin OR “soluble CD14 subtype” OR “sCD14-ST” OR P-SEP) AND (sepsis OR “bacterial infection” OR “systemic inflammatory response syndrome” OR ... See full document

... detect sepsis reported such as procalcitonin (PCT), C-reactive protein (CRP), lipopolysaccharide-binding protein (LBP), interleukins, provasopressin, and myeloid cells expressing triggering receptor-1 (TREM-1) ... See full document

... several meta-analyses of the diagnostic ac- curacy of presepsin in adult sepsis have been ...recent meta-analyses indicated pooled presepsin sensitivities and specificities each in the ... See full document

... effects meta-analyses were performed [21, 22] using the metandi package in STATA for index tests that included enough data to calculate sensitivity and specificity, with 95% confidence ...effects ... See full document

... This study had several limitations. First, the subjects were medical students with limited clinical experience, so the present findings may not be applicable to physicians with greater skill in performing physical ... See full document

... We searched for studies of treatment of depression with St John’s wort extract with no language restriction. All studies were required to meet the following inclusion criteria: 1) randomized controlled trials, 2) ... See full document

... Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cance[r] ... See full document

... of diagnosis were available from registry data, there are other clinical and disease-specific parameters that may influence choice and the timing of diagnostic ...definitive diagnosis among the ...this ... See full document

... Briefly, these are College of American Pathologists’ guide- lines that list indications for placental examination in three broad categories: maternal, fetal/neonatal, and placental. Preeclampsia, multiple gestation, and ... See full document

... this meta-analysis study, the use of learning cycle models in the educational process was examined academic achievements on students, and the remaining effects were excluded from the scope of the ...perform ... See full document

... The results showed that individual honeybees would, under certain circumstances, come together to form a cluster even in total darkness, and that as the number o[r] ... See full document

... Based on the sample area sub total household income the highest achieved by farmers of maize in district of Tabongo, that is Rp. 27,108,096, each is sourced from farming corn is Rp. 21,066,398, from farming to other ... See full document