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[PDF] Top 20 Activation of Mitogen Activated Protein Kinase pathways during the death of PC12 cells is dependent on the state of differentiation

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Activation of Mitogen Activated Protein Kinase pathways during the death of PC12 cells is dependent on the state of differentiation

Activation of Mitogen Activated Protein Kinase pathways during the death of PC12 cells is dependent on the state of differentiation

... NGF-differentiated PC12 cells deprived of NGF and serum (A) or NGF / cAMP- differentiated PC12 cells deprived of NGF and cAMP ...control cells or after 48 h of NGF / serum withdrawal ... See full document

9

Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF κB and mitogen activated protein kinase pathways

Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF κB and mitogen activated protein kinase pathways

... Briefly, cells were stained with TRAP (Acid Phos- phatase Kit 387-A; Sigma-Aldrich, ...control cells’ staining to allow the RPR and RANKL/M-CSF-treated cells to be ...TRAP-positive cells and ... See full document

9

Regulation of the mitogen activated protein kinase p44 ERK activity during anoxia/recovery in rainbow trout hypodermal fibroblasts

Regulation of the mitogen activated protein kinase p44 ERK activity during anoxia/recovery in rainbow trout hypodermal fibroblasts

... epithelial cells and ...inactive kinase to the nuclear compartment (Mizukami and Yoshida, ...was activated in response to reperfusion, suggesting an interface capable of ERK activation in the ... See full document

12

Mitogen-Activated Protein Kinase Pathways and Fungal Pathogenesis

Mitogen-Activated Protein Kinase Pathways and Fungal Pathogenesis

... scaffold protein Ste5 and a p21- activated protein (PAK) kinase, Ste20, and is essential for the activation of the Ste11-Ste7–Fus3/Kss1 ...cyclin- dependent kinase ... See full document

14

The Developmental and Adaptive role of Mitogen Activated Protein Kinase Pathways During Preimplantation Development

The Developmental and Adaptive role of Mitogen Activated Protein Kinase Pathways During Preimplantation Development

... gene activation (MGA), and together with compaction, is required for successful TE differentiation and blastocyst formation (Hamatani et ...‘inside’ cells surrounded by an ‘outside’ cell layer. The ... See full document

232

Pro-life role for c-Jun N-terminal kinase and p38 mitogen-activated protein kinase at rostral ventrolateral medulla in experimental brain stem death

Pro-life role for c-Jun N-terminal kinase and p38 mitogen-activated protein kinase at rostral ventrolateral medulla in experimental brain stem death

... shock protein 70 (HSP70) signaling pathway induced by hypoxia and tropomyocine receptor kinase B (Trk B)/Ras/Raf signaling pathways activated by brain- derived neurotrophic factor (BDNF) in ... See full document

12

Mitogen Activated Protein kinase signal transduction pathways in the prostate

Mitogen Activated Protein kinase signal transduction pathways in the prostate

... are activated that generally contribute to invasive potential, cell proliferation/differentiation, or survival in adverse ...and differentiation of PC3 cells. This protein is ... See full document

13

Vitamin C inhibits NF kappa B activation by TNF via the activation of p38 mitogen activated protein kinase

Vitamin C inhibits NF kappa B activation by TNF via the activation of p38 mitogen activated protein kinase

... some pathways to NF- ␬ B in ECV304s and HUVECs which we have previously shown to be insensitive to antioxidants (particularly IL-1) (29), we suspected that the effect of vitamin C was not dependent on its ... See full document

9

Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis like systemic inflammatory response in mice

Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis like systemic inflammatory response in mice

... maximal activation of these stress signaling ...immune activation triggered by flagellin, as indicated by the absence of sustained phosphorylation of ERK and I B a six hours after the injection of flagellin ... See full document

11

The role of IL-10 in Mycobacterium avium subsp. paratuberculosis infection

The role of IL-10 in Mycobacterium avium subsp. paratuberculosis infection

... the activation of macrophages with the production of reactive oxygen and nitrogen spe- cies, activation of T cells and maturation of DCs ...mice during BCG vaccination re- sulted in additional ... See full document

14

From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis

From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis

... signal-regulating kinase 1; AP-1-Jun: Activator protein-1-JUN; ATP: Adenosine triphosphate; BCG: Bacillus Calmette-Guerin; Bcl-2: B-cell lymphoma 2; CARD15: Caspase associated recruitment domain 15; CD4+: ... See full document

15

MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts

MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts

... chondrocytic cells [53]. It is well known that the activation of MAPK such as by JNK and cyclin-dependent kinase 4 is required for growth factor- induced phosphorylation of SMAD3 [54, ...SMAD3 ... See full document

11

Stem cells and the impact of ROS signaling

Stem cells and the impact of ROS signaling

... signaling pathways in stem cells via ROS and other metabolic ...stem cells and for the regeneration of ...stem cells ( pink background depicts the metabolic reactions and blue background ... See full document

13

Leptin receptors

Leptin receptors

... other pathways. MAPK kinases (mitogen-activated protein kinase), irS1 (insulin re- ceptor substrate-1), and phosphatidylinositol kinase (Pi3K) are important pathways ... See full document

5

Rabies Virus-Induced Activation of Mitogen-Activated Protein Kinase and NF-κB Signaling Pathways Regulates Expression of CXC and CC Chemokine Ligands in Microglia

Rabies Virus-Induced Activation of Mitogen-Activated Protein Kinase and NF-κB Signaling Pathways Regulates Expression of CXC and CC Chemokine Ligands in Microglia

... p38 activation in RV-infected ...p38 activation, sug- gesting that the RV-induced expression of CXCL10 and CCL5 is achieved by two distinct mechanisms, the direct activation of NF- ␬ B evoked by the ... See full document

12

Tyrosine kinase signalling in breast cancer: Epidermal growth factor receptor   convergence point for signal integration and diversification

Tyrosine kinase signalling in breast cancer: Epidermal growth factor receptor convergence point for signal integration and diversification

... MAPK activation by GPCR agonists [24 • ,31,33] and agonist-dependent α 2 -adrenergic receptor endocyto- sis [34] as an early step in G-protein-mediated signal gen- ...receptor activation ... See full document

7

Original Article Association detection between genetic variants in the microRNA binding sites of toll-like receptors signaling pathway genes and bladder cancer susceptibility

Original Article Association detection between genetic variants in the microRNA binding sites of toll-like receptors signaling pathway genes and bladder cancer susceptibility

... In rs72552316 (TLR7), the base transition from T to C may affect the binding process between miRNAs and the target region in 3’UTR of TLR7 . If miRNA loss combination to the corresponding miRNA binding site, the ... See full document

13

Expression and developmental requirement for transcription factor Sp2

Expression and developmental requirement for transcription factor Sp2

... the dentate gyrus (DG) of the hippocampus. Interestingly, these three regions correspond to sites of intensive neurogenesis in the developing mouse brain. For example: (1) neural stem cells (NSCs) within the ... See full document

205

Ligation of the T cell receptor complex results in activation of the Ras/Raf 1/MEK/MAPK cascade in human T lymphocytes

Ligation of the T cell receptor complex results in activation of the Ras/Raf 1/MEK/MAPK cascade in human T lymphocytes

... T cells with antibodies directed towards the T cell receptor complex results in the activation of mitogen-associated protein kinase ...Two pathways have been described in other ... See full document

8

Screening of potential diagnostic markers and therapeutic targets against colorectal cancer

Screening of potential diagnostic markers and therapeutic targets against colorectal cancer

... MBD2b protein-sepharose-4B column was used to enrich the methylated DNA frag- ...a proteinprotein interaction network was built using Search Tool for the Retrieval of Interacting Genes/Proteins ... See full document

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