[PDF] Top 20 Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation
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Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation
... upon TLR9 stimulation in com- parison to healthy donors as well as a lower expression of ...SLE B cells expressed significantly more TLR9 than B cells from healthy donors ... See full document
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Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus
... with TLR9 function in SLE B cells are currently ...of TLR9 protein in naive B cells from quiescent and active SLE patients was found to be similar to that in control ... See full document
12
Immune Aging Marker Associated with Periodontitis in Systemic Lupus Erythematosus Patients
... that systemic IL-10 had positive correlation with severity of ...and production many mediators. Myeloid cells are key target cells of IL-10 in infection stimulated alveolar bone ...the ... See full document
7
Enhanced IFN α production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosus
... dendritic cells (pDCs) are the main pro- ducers of IFN-α [32–35]. IFN-α production by human pDCs occurs mostly through the TLR7 and TLR9 signa- ling ...and TLR9 responds to DNA from viruses or ... See full document
11
Cytokine and autoantibody clusters interaction in systemic lupus erythematosus
... their production of Type I IFN ...Th17 cells although it is secreted by sev- eral immune cells ...immunomodulatory cytokine secreted by several cell populations although it exerts an essential ... See full document
15
Circulating exosomes from patients with systemic lupus erythematosus induce a proinflammatory immune response
... target cells is a common initial step in cell activa- tion, the activating molecules on the exosomes, wrapped spatially tightly together, might better cross-link the recep- tors on the target cells than in ... See full document
8
Decreased Gαq expression in T cells correlates with enhanced cytokine production and disease activity in systemic lupus erythematosus
... T cells from SLE patients ...T cells also show reduced proximal LAT phosphorylation, and in line with the present cytokine expression results, augmented immune responses, including increased ... See full document
9
Excessive activation of the TLR9/TGF β1/PDGF B pathway in the peripheral blood of patients with systemic lupus erythematosus
... the production of PDGF-B in healthy controls and SLE patients; it was found that blood cells of SLE patients did produce much higher levels of TGF-β1 and PDGF-B than those of healthy ...The ... See full document
12
DNA damage levels in systemic lupus erythematosus patients with low disease activity: An evaluation by comet assay
... strong response of oxidative/nitrosative stress markers in patients with higher SLEDAI, there were two groups: one with SLEDAI < 6 and other with SLEDAI ≥ 6, but they did not mention the maximum of their ... See full document
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Successful use of Ustekinumab in a Patient with Psoriasis, Psoriatic Arthritis and Systemic Lupus Erythematosus: A Case report and Review of literature
... positive lupus anticoagulant, AIHA that responded to rituximab and ...induced lupus was low because AIHA preceded any biological agent administration and thrombocytopenia preceded infliximab ... See full document
5
B cell abnormalities in systemic lupus erythematosus
... (BlyS/TNFSF13B) stimulation of B cells generates ISCs through two of its receptors – BCMA and BAFF-R – in a TD manner [9], and through its third receptor – TACI – in a TI manner ...mediated, ... See full document
6
Differential Diagnosis and Association of Acquired Immunodeficiency Syndrome and Systemic Erythematous Lupus: A Brief Review
... Acquired immunodeficiency syndrome and lupus erythematosus are multi- system diseases that can affect several organs and systems at different stages of disease evolution. Both diseases share common clinical ... See full document
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Secondary angle closure glaucoma by lupus choroidopathy as an initial presentation of systemic lupus erythematosus: a case report
... pathy, systemic immunosuppressive therapy should first be ...is associated with nephropathy and CNS ...from lupus-related complications [18]; thus, prompt and aggressive immunosuppressive therapy ... See full document
7
Role of endoplasmic reticulum stress in the protective effects of PPARβ/δ activation on endothelial dysfunction induced by plasma from patients with lupus
... NO production is impaired by plasma from patients with AN, stimu- lated by two agents, calcium ionophore A23187 and insulin, which stimulated eNOS by different ...NO production stimulated by both ... See full document
12
Neurological Manifestations Of Children With Systemic Lupus Erythematosus
... Neurological Manifestations Of Children With Systemic Lupus Erythematosus ORIGINAL ARTICLE Neurological Manifestations of Children with Systemic Lupus Erythematosus W F Loh, MRCP, I M I Hussain, FRCP,[.] ... See full document
5
Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus
... Systemic lupus erythematosus (SLE) is associated with premature and accelerated ...progenitor cells (CPCs) are circulating bone-marrow derived cells that play an important role ... See full document
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Fractionation of cells on a discontinuous Ficoll gradient Study of subpopulations of human T cells using anti T cell antibodies from patients with systemic lupus erythematosus
... with active systemic lupus erythematosus (SLE) had a decrease in a subpopulation of cells (fraction D) when peripheral blood lymphocytes were separated on a discontinuous Ficoll ...SLE ... See full document
12
Lupus Band Test in Systemic Lupus Erythematosus
... or more. A current laboratory activity score was constructed taking into account the presence of abnormalities in the following tests: ESR, platelet count, WBC, lymphocyte count, DNA binding, serum complement ... See full document
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SYSTEMIC LUPUS ERYTHEMATOSUS AND SYNDROMES POSSIBLY RELATED
... SYSTEMIC LUPUS ERYTHEMATOSUS AND SYNDROMES.. POSSIBLY RELATED![r] ... See full document
17
SYSTEMIC LUPUS ERYTHOMATOUS - A CASE STUDY IN AYURVEDIC SETTING .......
... are Lupus nephritis ranging from mild proteinuria to glomerulonephri- ...blood cells, anemia, leucopenia, thrombo- cytopenia, ...are Systemic fatigue, malaise, fever, anorexia, ... See full document
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