[PDF] Top 20 Adjuvant zoledronic acid therapy for patients with early stage breast cancer: an updated systematic review and meta-analysis

... of patients in the control group received zoledronic acid during follow-up, and it cannot be excluded that the effect of zoledronic acid on patient outcome was ...this meta- ... See full document

... summary, zoledronic acid has demonstrated consid- erable efficacy for preventing CTIBL in patients with early breast ...adding zoledronic acid to adjuvant endocrine ... See full document

... for patients with breast cancer (BC), the most commonly diagnosed cancer in American ...setting, patients are likely to develop bone metastases, a painful complication that can lead to ... See full document

... terms: early or adjuvant, breast can- cer or breast neoplasm, zoledronic acid or bisphospho- ...in breast cancer patients in adjuvant setting; (2) ZOL ... See full document

... in patients with bone metastases support the use of ZOL, pamidronate, or denosumab in patients with breast cancer; ZOL or denosumab in patients with any solid tumor; and ZOL in ... See full document

... a meta-analysis based on previous studies and not on patient ...and early breast cancer studies included in present study, and patients with metastatic breast ... See full document

... the meta-analysis of the Early Breast Cancer Trialists ’ Col- laborative Group (EBCTCG) showed that adjuvant BPs were associated with decreased fracture rate, as well as improved ... See full document

... of patients with potentially resectable disease over the past two decades, even after the effort of adjuvant therapy (AT) ...the early recurrence caused by micrometastases that were not ... See full document

... The most serious side effect of trastuzumab was improve- ment of congestive heart failure (CHF) (24), but some stud- ies stated that the risk of CHF for BC patients could be con- sidered zero (26). Furthermore, ... See full document

... IDC patients was ...on cancer stem cell markers (CD24 and CD44) in TNBC. All patients were diagnosed, treated and followed in a national referral oncology ...ensured therapy homogeneity ... See full document

... suppression, such as enzalutamide and abiraterone, will play an important role in the future. Similarly, these drugs are considered to offer more effective androgen deprivation against prostate tumor cells, but whether ... See full document

... loss. Cancer treatments with chemotherapy can lead to estrogen deficiency via gonadal dysfunction, and also impair bone health via direct effects on bone metabolism or systemic steroids commonly used as supportive ... See full document

... Some evidence suggested that women whose insurance data indicated nonadherence or nonpersistence over 1–5 years were more likely to have been hospitalized over the same period. These women may have not taken their ... See full document

... crossover therapy (i.e., postoperative radio- therapy for those who received preoperative chemotherapy and vice versa) was given to patients who were found to have unresectable or locally advanced ... See full document

... AKI patients with traditional indications, the advantages of commencing RRT in the absence of life-threatening complications are still under controversial ...that early initiation of RRT is related to ... See full document

... cost-utility analysis (CUA) using deci- sion analytic Markov model to calculate and compare the costs and utilities of using 1 year of adjuvant tras- tuzumab combined with standard chemotherapy ...chemo- ... See full document

... subgroup analysis of the NLR and overall survival, the results of the univariate and multivariate analyses were completely different, with different ...this meta-analysis suggests that NLR is a good ... See full document

... combination therapy had different mechanisms of action, not only against existing lesions but also against potential ...tion therapy extended the patient’s disease-free survival and overall survival, ... See full document

... when patients are treated with new schedules of breast ...in adjuvant WBI prospective trials, it could be crucial to have a quantitative easy reproducible tool for assessing and documenting late ... See full document

... Cancer patients are at increased risk of bleeding from anticoagulation, with an estimated 2-fold increased risk for major bleeding compared to non-cancer patients ...addition, cancer ... See full document