[PDF] Top 20 African Swine Fever Virus Infection in the Argasid Host, Ornithodoros porcinus porcinus
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African Swine Fever Virus Infection in the Argasid Host, Ornithodoros porcinus porcinus
... the virus titers in isolated organs, ticks were dissected under a binocular microscope and tissue samples were taken for determination of virus titer as ...of virus titer; this sample contained ... See full document
14
Macrophage Transcriptional Responses following In Vitro Infection with a Highly Virulent African Swine Fever Virus Isolate
... to infection by a virulent African swine fever virus (ASFV) isolate, Malawi ...One host gene showed increased expression levels at both 4 and 16 h postinfection compared to ... See full document
8
Small Rho GTPases and Cholesterol Biosynthetic Pathway Intermediates in African Swine Fever Virus Infection
... the host cell (14, 42, 48, 52) but also in viral morpho- genesis (27, 61), infection spreading (12), or virus-induced cell motility (61, ...ASFV infection takes place under these ...syncytial ... See full document
10
Deletion of a CD2-Like Gene, 8-DR, from African Swine Fever Virus Affects Viral Infection in Domestic Swine
... An African swine fever virus (ASFV) gene with similarity to the T-lymphocyte surface antigen CD2 has been found in the pathogenic African isolate Malawi Lil-20/1 (open reading frame ... See full document
9
African Swine Fever Virus Multigene Family 360 and 530 Genes Are Novel Macrophage Host Range Determinants
... Construction of recombinant ASFV Pr4 viruses containing deletions in MGF360 and MGF530 genes. Gene deletion mutants Pr4⌬2AB and Pr4V⌬2AB were generated by homologous recombination between ASFV Pr4 genomes and ... See full document
11
The Genetics of Life and Death: Virus-Host Interactions Underpinning Resistance to African Swine Fever, a Viral Hemorrhagic Disease
... following infection with highly virulent ASFV isolates (Gabriel et ...surviving infection with a moderately virulent isolate was shown to be higher than for younger pigs (Post et ...survived ... See full document
12
Processing and Localization of the African Swine Fever Virus CD2v Transmembrane Protein
... The virus CD2v protein shares with host CD2 the two predicted Ig superfamily (IgSF) domains, including an NH 2 - terminal V-like domain lacking the usual disulfide bridge and a membrane-proximal C-like ... See full document
12
The African Swine Fever Virus Thymidine Kinase Gene Is Required for Efficient Replication in Swine Macrophages and for Virulence in Swine
... African swine fever virus (ASFV) is a large icosahedral enveloped DNA virus and is classified as the only member of a new virus family, the Asfaviridae (3, ...the virus ... See full document
6
African Swine Fever Virus Is Wrapped by the Endoplasmic Reticulum
... ASF virus revealed several proteins with single N-terminal hydrophobic stretches of 20 amino acids, characteristic of signal peptides able to translocate the proteins into the lumen of the ...ASF virus, ... See full document
15
Dynamin- and Clathrin-Dependent Endocytosis in African Swine Fever Virus Entry
... into host cells showed that this internalization of virus particles is a temperature-, energy-, and low-pH-depen- dent process, since it does not occur at 4°C or in the presence of inhibitors of cellular ... See full document
10
Novel Swine Virulence Determinant in the Left Variable Region of the African Swine Fever Virus Genome
... the swine virulence determinant and macrophage host range ...that swine virulence determinant and macrophage host range determinant may have related functions in main- taining infected-cell ... See full document
10
A Nonessential African Swine Fever Virus Gene UK Is a Significant Virulence Determinant in Domestic Swine
... and virus yields in mac- rophage cell cultures ...a host range function in these cell types in ...ASFV infection (22, 29, 52). The fact that p15 is expressed early in virus-infected cells ... See full document
8
African Swine Fever Virus dUTPase Is a Highly Specific Enzyme Required for Efficient Replication in Swine Macrophages
... of infection and is localized in the cytoplasm of the infected ...parental virus in Vero cells but only to 10% or less of parental virus in swine ...for virus replication in dividing ... See full document
10
An IkappaB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages.
... evade host defenses, viruses have developed strategies to counteract antiviral ...cytokines. African swine fever virus (ASFV) is a large, double-stranded DNA virus that infects ... See full document
7
Intermediate class of mRNAs in African swine fever virus.
... of virus mRNAs selected by hybridization to dif- ferent genomic fragments showed the presence of two main temporal classes of ASFV genes ...of virus DNA replication, in a process that requires protein ... See full document
6
Unraveling the Armor of a Killer: Evasion of Host Defenses by African Swine Fever Virus
... after infection of macrophages (7), suggesting that this protein may also play a role in regulating programmed cell ...1 African swine fever virus in spleen samples from pigs infected ... See full document
6
African Swine Fever Virus Replication in the Midgut Epithelium Is Required for Infection of OrnithodorosTicks
... viral infection of the natural ...following infection of ixodid ticks with Thogoto virus (2) or Dugbe virus (3) but have been reported following infection of mosquitos with eastern ... See full document
12
Phenotype-Based Identification of Host Genes Required for Replication of African Swine Fever Virus
... African swine fever virus (ASFV) produces a fatal acute hemorrhagic fever in domesticated pigs that potentially is a worldwide economic ...six host genes whose cellular functions ... See full document
13
Characterization of the African Swine Fever Virus Decapping Enzyme during Infection
... poly(A) RNA, the cap structure, and ASFV-DP. COS-7 cells were infected with ASFV and a fluoresceinated oligo(dT) probe, the anti-cap antibody, and the anti-ASFV-DP anti- body were added to identify both viral and cellular ... See full document
19
First detection of African Swine Fever Virus in Ornithodoros porcinus in Madagascar and new insights into tick distribution and taxonomy
... 2.0. software (free download at http://www.clive.ed.ac. uk/winepiscope). It was based on the estimated total number of pig farms and the estimated proportion of pig farms to be detected as infested by O. porcinus, ... See full document
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