[PDF] Top 20 Allogeneic stem cell transplantation in patients with atypical chronic myeloid leukaemia: a retrospective study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

... negative chronic myeloid leukaemia (CML), usually called atypical CML (aCML), rep- resents a very rare disease entity with aggressive clinical char- acteristics that usually confer a dismal ... See full document

... previous retrospective study from Mohr et ...transplanted patients, which did not show any advantage compared to conventional therapy, with a 4-year probability of survival for the entire ... See full document

... 3 patients (2 patients with primary graft failure and one with secondary graft failure; one patient with missing ...29 patients (23%), manifested by a heterogeneous clinical presentation (Figure 1) ... See full document

... this study cohort, we used an objec- tive organ-specific symptom PRO to gain insight into the systemic response to ...of patients but with a general improvement in symptomatic scoring being reported in the ... See full document

... hematopoietic stem cell transplant is the only potentially curative option for patients with acute mye- loid leukemia (AML) in primary induction failure or re- fractory ...of patients ... See full document

... a retrospective study performed by the Acute Leukemia Working Party (ALWP) of the European Group for Blood and Marrow Transplantation (EBMT) group and by ... See full document

... bone marrow biopsy procured in April 2014 showed osteosclerosis and fibrosis grade 3, monolobu- lated bizarre megakaryocytes, increased erythropoiesis and myelopoiesis with reduced maturation, but no in- crease in ... See full document

... ectly from the EBMT registry supplemented by a standardised ques- tionnaire completed by the treating clinicians in each ...primary study endpoint was clinical disease response [deined below] assessed by ... See full document

... more patients) and twenty-two case reports (with one or two patients) were identified as relevant for the ...8 patients (n = 6), 15 studies were selected for further detailed ...one study that ... See full document

... 65 patients with relapsed AML using augmented cytarabine based chemotherapy prior to ...these patients, and the median period between relapse and DLI was 19 ...of patients achieved a CR with DLI, yet ... See full document

... Mit einem Anteil von 88% war das periphere Blut des Spenders der Haupt- Entnahmeort der im Verlauf transplantierten Stammzellen. Es ergaben sich signi- fikant bessere Überlebenszeiten gegenüber der Verwendung von ... See full document

... our study merit ...of patients taking posaconazole for prophylaxis of IFI with and without TDM are limited, so we are not able to validate the practical benefit of posacona- zole TDM in clinical up to ... See full document

... Given the difficulty of diagnosing hypothyroidism in patients whose complaints (asthenia, cold intolerance, etc.) can easily be attributed to the causal disease or chemotherapy itself, it is important to regularly ... See full document

... hematopoietic stem cell transplantation (allo-HSCT) is the only curative treatment for intermedi- ate/high-risk MDS and acute myeloid leukemia ...poietic stem cell ... See full document

... post-treatment cell counts and serum creatinine between two groups; these were analyzed using the paired ...in patients treated with Valganciclovir and Fos- carnet, compared with ... See full document

... Allo-HSCT is a very effective treatment option for patients with hematological malignancies who have HLA matched donors. The median time to engraftment was 19 days. The TRM was 19.5%, with infectious ... See full document

... Our study demonstrated that the proportion of γδTregs was signifi- cantly increased following G-CSF and/or TGF-β induc- ...lymphoma cell lines in the three induction and control groups did not significantly ... See full document

... EBV infection is considered to play a vital role in contributing to the development of DLBCL in AITL patients because of immunodeficiency [9]. However, EBER and serological evaluation of EBV DNA were both negative ... See full document

... resolution computed tomography patterns correlate with histolo- gical changes: including: (i) non-speci fi c interstitial pneumonia, which is the most commonly observed and characterized by a mixture of ground glass ... See full document

... neutropenic patients or those with refractory invasive fungal disease, there was no further increase in exposure when the dose was increased from 400 mg to 600 mg twice daily ... See full document