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[PDF] Top 20 Analysis of gene expression in normal and neoplastic keratinocytes

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Analysis of gene expression in normal and neoplastic keratinocytes

Analysis of gene expression in normal and neoplastic keratinocytes

... differential gene expression as yet (although many of the large companies that have bought into the technology would like you to think ...in expression in very rare transcripts, and contrary to ... See full document

174

Comparative analysis of gene expression in normal and cancer human prostate cell lines

Comparative analysis of gene expression in normal and cancer human prostate cell lines

... in normal epithelial cells PNT2 and prostate cancer cell lines LNCaP, DU145 and PC3, produced from tumors with different aggressiveness and metas tatic ...Relative gene expression of 65 can- ... See full document

10

Prediction of the gene expression in normal lung tissue by the gene expression in blood

Prediction of the gene expression in normal lung tissue by the gene expression in blood

... influence gene expression in lung [18, 19] and blood ...in gene expres- sion: for genes whose expression in blood and lung changes similarly in response to tobacco smoke expos- ure, the ... See full document

6

Integrated eicosanoid lipidomics and gene expression reveal decreased prostaglandin catabolism and increased 5‐lipoxygenase expression in aggressive subtypes of endometrial cancer

Integrated eicosanoid lipidomics and gene expression reveal decreased prostaglandin catabolism and increased 5‐lipoxygenase expression in aggressive subtypes of endometrial cancer

... TMAs were constructed from formalin-fixed paraffin-embedded (FFPE) specimens using 3 x 0.6 mm cores/sample. Control TMAs included multiple normal human tissues. Antibodies to eicosanoid metabolic enzymes were ... See full document

57

Integrated analysis reveals key genes with prognostic value in lung adenocarcinoma

Integrated analysis reveals key genes with prognostic value in lung adenocarcinoma

... fied. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses showed that upregulated DEGs were significantly enriched in cell cycle, p53 pathway, and extracellular matrix–receptor interactions; ... See full document

12

The effect of Rho kinase inhibition on long-term keratinocyte proliferation is rapid and conditional

The effect of Rho kinase inhibition on long-term keratinocyte proliferation is rapid and conditional

... adult keratinocytes isolated from cutaneous skin and cultured for either three or four passes (two replicates: two different passes of cells from one individual) in the presence or absence of 10 μM ...and ... See full document

11

Comprehensive analysis of gene-expression profile in chronic obstructive pulmonary disease

Comprehensive analysis of gene-expression profile in chronic obstructive pulmonary disease

... three normal samples, was obtained from Gene Expression ...for gene-ontology and pathway-enrichment analyses using the Database for Annotation, Visualization and Integrated Discovery ...HLA-A ... See full document

7

Altered PTEN expression; a diagnostic marker for differentiating normal, hyperplastic and neoplastic endometrium

Altered PTEN expression; a diagnostic marker for differentiating normal, hyperplastic and neoplastic endometrium

... altered gene in endometrial tumors of endometrioid histology show- ing microsatellite instability is PTEN inactivation and sev- eral studies have found that PTEN inactivation is correlated with clonal growth ... See full document

6

Expression of Bcl 2 and Bcl 2 Ig fusion transcripts in normal and neoplastic cells

Expression of Bcl 2 and Bcl 2 Ig fusion transcripts in normal and neoplastic cells

... We examined the expression of the Bcl-2 gene at chromosome segment 18q21, that is translocated into the Ig heavy chain gene locus in t(14;18) bearing lymphomas. Bcl-2, while B cell associated, is ... See full document

5

Expression of Cyclooxygenase 2 and Ki 67 in Actinic Keratosis and Cutaneous Squamous Cell Carcinoma in Dogs

Expression of Cyclooxygenase 2 and Ki 67 in Actinic Keratosis and Cutaneous Squamous Cell Carcinoma in Dogs

... COX-2 expression showed a diffuse cytoplasmic pat- tern in keratinocytes, being evident around nuclear mem- ...COX-2 expression in neoplastic keratino- ...COX-2 expression in ... See full document

7

The effect of erythropoietin on normal and neoplastic cells

The effect of erythropoietin on normal and neoplastic cells

... mRNA expression outside the erythroid compartment using RT-PCR analysis, the mice developed normally and had normal organ function and ...for normal nonhematopoietic organ develop- ment, and ... See full document

27

Differentiation of nonhuman primate pluripotent stem cells into functional keratinocytes

Differentiation of nonhuman primate pluripotent stem cells into functional keratinocytes

... (B) Gene expression profiles analyzed by RT-qPCR analysis for pluripotency markers cMYC , KLF4 , OCT4 , SOX2 and NANOG , and the three germ layer markers AFP , CDX2 , GATA4 , GATA6 , NESTIN and KRT5 ... See full document

7

The Role of CDKs in Normal and Neoplastic Proliferation

The Role of CDKs in Normal and Neoplastic Proliferation

... overexpression of CDK2 does not result in early progression to squamous cell carcinomas under a two-stage carcinogenesis protocol in either K5CDK2 or K5CDK4 D158N mice. In fact, both K5CDK2 and K5CDK4 D158N transgenic ... See full document

231

Regulation of parathyroid hormone like peptide in cultured normal human keratinocytes  Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion

Regulation of parathyroid hormone like peptide in cultured normal human keratinocytes Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion

... production which was associated with an increase in cellular differentiation as assessed by production of high molecular weight keratin. To investigate whether these factors were acting at the level of transcription of ... See full document

11

MicrosatelliteInstabilitywithin the CD30GenePromoter Distinguishes between NormalandNeoplastic CellsinLymphoma

Microsatellite Instability within the CD30 Gene Promoter Distinguishes between Normal and Neoplastic Cells in Lymphoma

... 5]. Expression of CD30 in healthy individuals occurs only weakly on the surface of activated lymphoid cells, in particular, activated peripheral blood B and T cells and small numbers of cells in the mantles of ... See full document

11

Interleukin 6 gene expression in normal and neoplastic B cells

Interleukin 6 gene expression in normal and neoplastic B cells

... IL-6 gene is expressed in anti-Ig-activated and neoplastic B ...peak expression occurring at 4 h and declining rapidly ...mRNA expression was in non-B cells, T cells and monocytes were ... See full document

8

Expression of ADAMTS 8, a secreted protease with anti angiogenic properties, is down regulated in brain tumours

Expression of ADAMTS 8, a secreted protease with anti angiogenic properties, is down regulated in brain tumours

... the expression of ADAMTS-8, a secreted protease with antiangiogenic properties, in brain ...equivalent expression of ADAMTS-8 was found in normal whole brain, cerebral cortex, frontal lobe, ... See full document

8

Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model

Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model

... the expression of most cancer-related genes in HMC-LTR to the levels in pri- mary cells (Additional file 1: Figure ...ChIP-seq analysis in HMC-LT further showed that the increased LOCKs by KDM3A/JMJD1A ... See full document

15

Galectin 3 immunohistochemical expression in neoplastic and non neoplastic lesions of thyroid

Galectin 3 immunohistochemical expression in neoplastic and non neoplastic lesions of thyroid

... Gal-3 expression in this kind of tumor, we could also possibly hypothesize that a false negative result yielded when the areas negative for Gal-3 are ...Gal-3 expression or have absolutely no ... See full document

6

Immunohistochemical Study of MUC1 and MUC5AC Expression in Gall Bladder Lesions

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... Pyloric metaplasia and intestinal metaplasia was seen in 40.22% (253/629) and 12.24% (77/629) cases of GBLs as seen in literature [19]. Pyloric metaplasia was seen in 224 cases of CCC, 15 cases of ACC and 14 cases of GB ... See full document

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