[PDF] Top 20 Analysis of genome wide association data by large scale Bayesian logistic regression
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Analysis of genome wide association data by large scale Bayesian logistic regression
... Single-locus analysis is often used to analyze genome-wide association (GWA) data, but such analysis is subject to severe multiple comparisons ...Multivariate logistic ... See full document
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A "candidate interactome" aggregate analysis of genome wide association data in multiple sclerosis
... pathogenesis) analysis of genome-wide association data in multiple ...last genome-wide association study of the International Multiple Sclerosis Genetics Consortium ... See full document
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A "Candidate Interactome" Aggregate Analysis of Genome Wide Association Data in Multiple Sclerosis
... pathogenesis) analysis of genome-wide association data in multiple ...last genome-wide association study of the International Multiple Sclerosis Genetics Consortium ... See full document
9
Causal graph-based analysis of genome-wide association data in rheumatoid arthritis
... Kurreeman FA, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos CI, Ardlie KG, Barton A, Bowes J, Brouwer E, Burtt NP, Catanese JJ, Coblyn J, Coenen MJ, Costenbader KH, Criswell LA, Crusius JB, Cui J, de ... See full document
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Bayesian Approach for Nonlinear Dynamic System and Genome-Wide Association Study
... Bayesian framework. As in GWAS for schizophrenia, about 500k tests are carried out, for which the multiple testing issue becomes a major concern. The gene-based GWAS will dramatically reduce the number of tests. ... See full document
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Comparison of HapMap and 1000 genomes reference panels in a large scale genome wide association study
... in Genome Epidemiology (CHARGE) Consortium in development and support of this manu- ...and data handling, in addition to the laboratory staff at the Lud- wigshafen General Hospital and the Universities of ... See full document
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A LASSO penalized regression approach for genome wide association analyses using related individuals: application to the Genetic Analysis Workshop 19 simulated data
... the Bayesian information criterion (BIC) was used to select the best model, the Ind model resulted in 15 significant SNPs, whereas both the Add and the Add-Dom models included, on average, approximately 7 ... See full document
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Identifying Transcription Factor Targets and Studying Human Complex Disease Genes
... general large-scale genome-wide approaches are unbiased and efficient to find disease ...a large number of ...gene analysis to identifying susceptibility ...identified ... See full document
182
Regularized regression method for genome wide association studies
... disequilibrium between adjacent markers. This method uses a penalty on the difference of the genetic effect at adjacent single-nucleotide polymorphisms and combines it with the minimax concave penalty, which has been ... See full document
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Regression-based multi-marker analysis for genome-wide association studies using haplotype similarity
... haplotype analysis consumes more degrees of freedom per test than a single-SNP ...The large degrees of freedom can limit the power of a haplotype association test, and the overall performance of a ... See full document
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Genome wide association analyses of the 15th QTL MAS workshop data using mixed model based single locus regression analysis
... a large number of pseudo significant SNPs were identified on this chromosome, the LD levels between the most effective SNP and other 62 significant SNPs (Figure 2) showed that 47 of them are in strong LD (D’ ... See full document
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PhenX Measures for Data Sharing, Cross-study Analysis and Data Interoperability
... • The goal of PhenX is to select and define high priority measures useful for Genome-wide association studies (GWAS) and other large-scale genomic research efforts.. • The development [r] ... See full document
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Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis
... clinical data (eg, length of Barrett’s oesophagus segments, presence of low-grade dysplasia), and application of modern polygenic score approaches will help to identify patients with Barrett’s oesophagus at higher ... See full document
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Association between 17q25.3-rs6465657 polymorphism and prostate cancer susceptibility: a meta-analysis based on 19 studies
... the association between ...overall analysis suggested that the C allele of rs6465657 significantly associ- ated with the increased risk of ...subgroup analysis stratified by ethnicity, the rs6465657C ... See full document
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Association between apolipoprotein B genetic polymorphism and the risk of calcific aortic stenosis in Chinese subjects, in Xinjiang, China
... the association between the SNPs (rs693 and rs6725189) and CAS risk (Table ...Multiple logistic regression were used to adjust con- founding ... See full document
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Large scale genome wide association studies and meta analyses of longitudinal change in adult lung function
... regulatory lipid transfer domain protein superfamily, and is involved in the trafficking of cholesterol and other lipids between intracellular membranes.[29] Recent in vitro studies showed increased STARD5 expression and ... See full document
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Genetic Influences on Evening Preference Overlap with Those for Bipolar Disorder in a Sample of Mexican Americans and American Indians
... Previous large-scale genome-wide association studies (GWAS) aimed at identifying genetic influences on diurnal preference have exclusively included subjects of European ...chip ... See full document
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Inter-chromosomal variation in the pattern of human population genetic structure
... level analysis detected subtle forms of population structure within continental populations, and as many as 31 PCs were required to classify individuals into homo- geneous ...the genome were ...network ... See full document
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Structured Genome-Wide Association Studies with Bayesian Hierarchical Variable Selection
... GWAS analysis on imaging phenotypes related to AD, and our goal is to identify genetic markers that are associated with imaging traits, and to further assess their predictive ...MRI data were collected ... See full document
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Genome wide association analysis of the QTL MAS 2012 data investigating pleiotropy
... the data were corrected for a polygenic component containing the genomic- based kinship ...a regression analysis, to achieve genome-wide rapid association ... See full document
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