[PDF] Top 20 Analysis of the role of the Rac/Cdc42 GTPases during planar cell polarity generation in Drosophila

... the GTPases of the Rho subfamily function upstream the JNK module and that they act in parallel ...and Cdc42 might receive a different activating input, as they do not show genetic interactions with ... See full document

... whereas Rac and Cdc42 GTPases have been previously implicated in various axon growth and guidance processes in the nematode (Lundquist et ...and Drosophila (Hakeda-Suzuki et ...Rho ... See full document

... epithelial polarity, such as bazooka or discs large, in which apical markers are found around the entire cell surface (Abdelilah-Seyfried et ...of cell polarity in absence of contact with the ... See full document

... Apico-basal polarity is typical of cells present in differentiated epithelium while front-rear polarity develops in motile ...migratory polarity may be seen as the hallmark of cancer progression to ... See full document

... the Drosophila eye. The analysis of sal – mosaics reveals that sal is specifically required in R3 for establishment of ommatidial chirality ...The analysis of sal – clones in the larval eye reveals ... See full document

... major role in the formation of this class of sense ...a role in the formation of the ground state ...a role in EGFR-mediated recruitment of oenocytes as well as recruit- ment of secondary ch ...a ... See full document

... of Drosophila, including controlling growth of imaginal discs, planar cell polarity (PCP) and the proximodistal patterning of ...structure-function analysis of Ft and Ds, separating ... See full document

... mediate cell-cell adhesions, the core PCP complexes are sorted asymmetrically along the mediolateral axis of the ...cochlea. Cell-cell communications reinforce the sorting of core PCP proteins ... See full document

... in Drosophila pupal wing cells, which are arranged in a regular hexagonal lattice (between 20 and 24 hours ...each cell, Pk and Vang to the proximal edge (Strutt and Strutt, ...in cell morphology or ... See full document

... a Cdc42, Par6 and PKCζ complex, which through its action on Gsk3β and adenomatous polyposis coli (APC) regulates the microtubular network and thereby directed movement of cells (Etienne-Mannevielle and Hall, ... See full document

... associated cell borders. (F,G) Snapshot of a single cell co-occurrence analysis in WT (F) and in PCP mutant (G) ...of polarity and distribution in those PPE tested conditions (fritz/mwh/Drok), ... See full document

... the role of cofilin/ADF, other factors required for reorganization of the actin cytoskeleton would be expected to be required for establishment of ...signaling. During wing hair formation, a signal ... See full document

... individual cell showing few signs of neuronal differentiation (elliptical shape, bipolar protrusions) is followed ...precursors during development, which could influence the final number and/or the spacing ... See full document

... With more and more residents into self-employment, then their economy will be independent, not to be dependent on the capitalist economic system, in this case the Government has to be pro active provides capital for ... See full document

... the Bangalees by the Pakistan military was like the head hiding camel bird. It was Pakistani Propaganda which was mainly responsible for their attitude like this. Yahya was able to sell his ideas to the Arab leaders that ... See full document

... diplomatic role of the Secretariat. The part will also discuss the role of the UN Secretariat in light of the UN principles on the use of force, dispute settlement and regulation of armaments with a special ... See full document

... in Drosophila encode large, cadherin-related proteins (Clark et ...processes during Drosophila development, including the regulation of growth and the proximodistal patterning of appendages (Bryant ... See full document

... Rho GTPases are key integrat- ing molecules from different extracellular signals, as they can be activated by different ...active GTPases can interact with a plethora of different effectors which mediate ... See full document

... As discussed previously, asymmetric distribution of Numb and Lgl into the pIIb cell is required for cell-autonomous Notch inhibition. However, the mechanism by which Numb or Lgl mediates this inhibition is ... See full document

... We also observed Fz (but not Stbm) localised to the migratory edges of the border cells, both prior to and during migration (Fig. 5B,D). Fz localisation has not previously been observed in migrating cells, but ... See full document