[PDF] Top 20 Analysis of long terminal repeat circle junctions of human immunodeficiency virus type 1.
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Analysis of long terminal repeat circle junctions of human immunodeficiency virus type 1.
... For HIV, the first 18 nucleotides of the 3' terminus of the tRNALYS, including the CCA sequences added posttranscriptionally, base pair with the viral RNA 24 and serve as the primer for [r] ... See full document
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Longitudinal Analysis of Human Immunodeficiency Virus Type 1 nef/Long Terminal Repeat Sequences in a Cohort of Long-Term Survivors Infected from a Single Source
... The molecular mechanisms underlying the increased or ac- quired pathogenicity of nef/LTR-deleted HIV-1 harbored by slow progressors D36 and C98 remain to be determined, but possibilities include changes in LTR or ... See full document
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Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat.
... LTR transcriptional activity obtained by using NXS mutants in Jurkat cells Spl, TATA, LBP-1, UBP-2 a NRE, Negative regulatory element; IL-2, interleukin-2; IL-2Ra, interleukin-2 receptor[r] ... See full document
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In vivo footprinting analysis of constitutive and inducible protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1.
... Involvement of the HIV-1 enhancer in transcriptional activation of HIV-1 by mitogens and cytokines has already been observed in different experimental systems by in vitro protein binding[r] ... See full document
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A model system for human cytomegalovirus-mediated modulation of human immunodeficiency virus type 1 long terminal repeat activity in brain cells.
... Table 1. In the absence of IPTG, HIV-1 RNA levels remained low, and HCMV had no effect on LTR-directed transcription in the LIGHIVDC cells (compare lanes 1 and 2 in ... See full document
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The kappaB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth.
... of human immunodeficiency virus type 1 (HIV-1) on its NF- k B binding sites ( k B sites) for replication in transformed and primary T-cell targets was examined by infecting cells ... See full document
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Genotypic and phenotypic characterization of long terminal repeat sequences from long-term survivors of human immunodeficiency virus type 1 infection.
... consistent. Analysis of transcriptional activity of the LTR in the context of the whole infectious ...cells. Virus concentration in the culture supernatant was standardized by measuring the p24 ... See full document
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Functional Differences between the Long Terminal Repeat Transcriptional Promoters of Human Immunodeficiency Virus Type 1 Subtypes A through G
... current human immunodeficiency virus type 1 (HIV-1) shows an increasing number of distinct viral subtypes, as well as viruses that are recombinants of at least two ... See full document
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IRF-1 Is Required for Full NF-κB Transcriptional Activity at the Human Immunodeficiency Virus Type 1 Long Terminal Repeat Enhancer
... RT-PCR analysis was performed for SeV N protein on RNA extracts from 10-h SeV-infected control and IRF-1 siRNA-expressing Jurkat ...blot analysis of IRF-1 levels was performed on whole-cell ... See full document
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Molecular and functional interactions of transcription factor USF with the long terminal repeat of human immunodeficiency virus type 1.
... the analysis of the USF binding sites by the random oligonucleotide selection procedure showed that the E box motif is almost absolutely required for binding ... See full document
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Repression in vitro, by human adenovirus E1A protein domains, of basal or Tat-activated transcription of the human immunodeficiency virus type 1 long terminal repeat.
... ; 1 to 25 of E1A for in vivo association is the 300-kDa cellular protein p300 (for a review, see reference ...functional analysis has revealed that p300 lacking an intact E1A-binding site can overcome E1A ... See full document
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Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator.
... At 1 m M, Ro 5-3335 completely inhibited Tat-dependent stimulation of the HIV-1 LTR by T3 and synergistically activated the HIV-1 LTR with T3 in the absence of ... See full document
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An integration-defective U5 deletion mutant of human immunodeficiency virus type 1 reverts by eliminating additional long terminal repeat sequences.
... 12D7 CEM cells were infected with equal amounts RT activity of wild-type, HIV1U5/604de1' and revertant HIV-1U5/604del-rev4 viruses, and Hirt supernatant DNAs, harvested at 0,5 , 11, and [r] ... See full document
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TFII-I Regulates Induction of Chromosomally Integrated Human Immunodeficiency Virus Type 1 Long Terminal Repeat in Cooperation with USF
... the binding of USF1 and USF1/USF2 heterodimers to the RBEIII element in vitro (Fig. 5). This observation is consistent with previous re- sults showing that TFII-I can stimulate the binding of USF1 to the adenovirus ML E ... See full document
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Cytoplasmic APOBEC3G Restricts Incoming Vif-Positive Human Immunodeficiency Virus Type 1 and Increases Two-Long Terminal Repeat Circle Formation in Activated T-Helper-Subtype Cells
... Human APOBEC3G (A3G) is a cytidine deaminase that limits endogenous retrotransposition, as well as replication of multiple retroviruses including human immunodeficiency virus type ... See full document
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Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat.
... 139-149 0022-538X/92/010139-11$02.00/0 Copyright X 1992, American Society for Microbiology Functional Roles for the TATA Promoter and Enhancers in Basal and Tat-Induced Expression of the[r] ... See full document
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Expression of a human immunodeficiency virus type 1 long terminal repeat/simian virus 40 early region fusion gene in transgenic mice.
... We investigated the in vivo tissue specificity of the HIV-1 transcription control elements by introducing a hybrid reporter gene containing the HIV-1 LTR fused to the simian virus 40 SV4[r] ... See full document
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Evolution of human immunodeficiency virus type 1 nef and long terminal repeat sequences over 4 years in vivo and in vitro.
... 225 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The evolution of an 851-bp segment of the human immunodeficiency virus type 1 HIV-1 genome encoding the nef open rea[r] ... See full document
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C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes.
... LPS and PMA act through different signal transduction pathways (2, 4, 59). To determine whether C/EBP sites were important in the induction of the HIV-1 LTR in response to activation by more specific stimuli, U937 ... See full document
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Targeted Derepression of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat by Pyrrole-Imidazole Polyamides
... In summary, we show that RCS-binding polyamides targeted to the HIV LTR can inhibit LSF binding to the RCS in vitro and can increase expression of the LTR. RCS-binding poly- amides selectively upregulate expression of ... See full document
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