[PDF] Top 20 Antibody Responses of Pigs to Defined Erns Fragments after Infection with Classical Swine Fever Virus
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Antibody Responses of Pigs to Defined Erns Fragments after Infection with Classical Swine Fever Virus
... Classical swine fever virus (CSFV) is an enveloped positive- stranded RNA virus (20) of the genus Pestivirus of the Flavi- viridae family ...diarrhea virus and Border disease ... See full document
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Comparative analyses of host responses upon infection with moderately virulent Classical swine fever virus in domestic pigs and wild boar
... Upon infection, all animals showed a down regulation of CD2 + CD21+ cells (phenotype of naïve B-cells), this could be either due to depletion or an indication of B-cell ...domestic pigs showed an increase ... See full document
6
Enzyme-Linked Immunosorbent Assay Based on a Chimeric Antigen Bearing Antigenic Regions of Structural Proteins Erns and E2 for Serodiagnosis of Classical Swine Fever Virus Infection
... (32). Pigs infected with CSFV can develop various forms of illness: acute, subacute, subclin- ical, chronic, and late onset (8, ...domestic pigs largely rely on the early diagnosis of infection ... See full document
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Mutation of Cysteine 171 of Pestivirus Erns RNase Prevents Homodimer Formation and Leads to Attenuation of Classical Swine Fever Virus
... an infection experiment in ...observed after infection with the CSFV Alfort/Tu ¨bingen mutant V-C171d with those seen in wt CSFV Alfort/Tu ¨bingen-infected ...latter virus was recov- ered from ... See full document
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Efficacy of a live attenuated vaccine in classical swine fever virus postnatally persistently infected pigs
... Classical swine fever (CSF) causes major losses in pig farming, with various degrees of disease ...against classical swine fever virus (CSFV) are used routinely in endemic ... See full document
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Passage of Classical Swine Fever Virus in Cultured Swine Kidney Cells Selects Virus Variants That Bind to Heparan Sulfate due to a Single Amino Acid Change in Envelope Protein Erns
... Brescia. After cloning and one or two additional passages in SK6 cells, seven virus clones (clone A, passage number 3 [p3], and clones B to G, passage number 2 [p2]) were tested for inhibition by ...inhibit ... See full document
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Deletions of Structural Glycoprotein E2 of Classical Swine Fever Virus Strain Alfort/187 Resolve a Linear Epitope of Monoclonal Antibody WH303 and the Minimal N-Terminal Domain Essential for Binding Immunoglobulin G Antibodies of a Pig Hyperimmune Serum
... ELISA and for its ability to bind WH303 in a dot blot. As shown in Fig. 4, pep 415 was capable of inhibiting WH303 from binding to E2AB in a concentration-dependent manner. Con- sistent with the ELISA result was the ... See full document
7
Mutations in Classical Swine Fever Virus NS4B Affect Virulence in Swine
... of classical swine fever virus (CSFV), the etiological agent of a severe, highly lethal disease of ...in swine macrophages, including a significant sustained accumulation of ... See full document
14
Epidemiological considerations on African swine fever in Europe 2014–2018
... The infection survived locally in the wild boar population independently from outbreaks in do- mestic pigs, with a steady and low prevalence below 5% and a local transmission speed of 2–5 km/month ... See full document
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African Swine Fever Virus Infection of Porcine Aortic Endothelial Cells Leads to Inhibition of Inflammatory Responses, Activation of the Thrombotic State, and Apoptosis
... of infection, and procoagulation factors, which are involved in initiation of the blood clotting ...so after 4 and 24 h of TNF-␣ ...h after TNF-␣ treatment and remained high for 24 ... See full document
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Porcine RING Finger Protein 114 Inhibits Classical Swine Fever Virus Replication via K27-Linked Polyubiquitination of Viral NS4B
... Currently, few studies have reported on the interactions between flaviviral NS4B and cellular proteins, possibly due to the lower significance of NS4B in the flavivirus life cycle than of other nonstructural proteins, such ... See full document
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The E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in Swine
... in swine virulence, the presence of additional CSFV virulence determinants outside the E2 region is ...CS virus, a vaccine virus safely used for more than 30 years (40), it is not surprising that CS ... See full document
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Generation and Efficacy Evaluation of a Recombinant Pseudorabies Virus Variant Expressing the E2 Protein of Classical Swine Fever Virus in Pigs
... lassical swine fever (CSF), an economically important infec- tious disease of pigs, is caused by classical swine fever virus (CSFV), which belongs to the Pestivirus genus ... See full document
9
Differential expression of porcine microRNAs in African swine fever virus infected pigs: a proof of concept study
... innate responses by determining the tropism, virulence and suppression of type I IFN response ...The virus uses the ER as a site of replication and this process of activation of ATF6 can trigger ER stress ... See full document
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Biosynthesis of Classical Swine Fever Virus Nonstructural Proteins
... week after each booster ...proteins. After seroconversion, mice were finally boosted with 20 g protein on the following 3 days without ...37°C. After- wards the cells were grown in DMEM ... See full document
14
Classical Swine Fever Virus p7 Protein Is a Viroporin Involved in Virulence in Swine
... C virus (HCV) p7 ...influenza virus M2 proteins, may function as a viroporin involved in pore formation and transport of ions across cell membranes (1, ...for virus production but not for RNA ... See full document
14
Discovering up-regulated VEGF–C expression in swine umbilical vein endothelial cells by classical swine fever virus Shimen
... Currently, deep sequencing technology is used for large-scale analysis of gene expression. In our study, we expected to reveal important genes involved in the host cell response to CSFV Shimen infection using DGE ... See full document
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Zani, Laura (2018): Biological and genomic characterization of recent African swine fever strains and field validation of surveillance tools. Dissertation, LMU München: Tierärztliche Fakultät
... An introduction of the disease into naïve populations would lead to a high number of fallen wild boar. Therefore, hunters are told to report these carcasses to the local veterinary service and sample them for diagnostic ... See full document
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Classical Swine Fever Virus ErnsDeletion Mutants: trans-Complementation and Potential Use as Nontransmissible, Modified, Live-Attenuated Marker Vaccines
... Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), an economically important disease of domestic pigs and wild ...by ... See full document
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A decade of research into classical swine fever marker vaccine CP7_E2alf (Suvaxyn® CSF Marker): a review of vaccine properties
... and virus isolation was not possible from the animals post ...short fever, mild leu- kopenia, and depression over a few days were ...weeks after far- rowing, groups of piglets were either orally or ... See full document
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