[PDF] Top 20 IN VITRO AND IN VIVO ANTIHEPATOTOXIC ACTIVITY OF OROXYLUM INDICUM AGAINST CARBON TETRACHLORIDE INDUCED HEPATIC DAMAGE

... Hepatoprotective activity: For in-vitro hepatoprotective activity studies, rat liver was extracted and explant cultures were done by growing rat hepatocytes in Dulbeccos Modified Eagle’s Medium ... See full document

... ployed for assessing the antihepatotoxic activity. They were procured from the Central Animal House of Jamia Hamdard, New Delhi Sanction Letter No. (173/CPCSEA), after approval under the project proposal ... See full document

... Trichosanthes cucumerina Var cucumerina L(cucurbitaceae) is a slender hispid climber distributed in various parts of India and also in Srilanka, tropical Himalaya, Malesia, Polynesia and N. Australia. It is one agent ... See full document

... generated even in normal physiological conditions and human beings possess the inbuilt natural antioxidant enzymes such as SOD, CAT, GPX, GST, and GGT to scavenge the generated free radicals. However, during prolonged ... See full document

... anticancer activity in vitro in DU-145 and PC-3 prostate cancer and in COLO-205 colon cancer cell lines by MTT ...potent activity (% Inhibition ...anticancer activity in vitro in colon ... See full document

... Oral acute toxicity study in wistar rats were carried out for methanolic extract of Averrhoa bilimbi in accordance with OECD guideline no.423 and LD50 of the extract was found to be 5000 mg/kg b.w. One tenth of this ... See full document

... Lycopene is an effective antioxidant obtained from tomato extracts and has been proved to be potent free radicals scavenger in various in vivo as well as in vitro studies. Tomatoes are predominant source of ... See full document

... 1- Karthikeyan A, Shanthi V, Nagasathaya A. Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica. L. Int. J. Green Pharm. 2009; 3: 78-80. 2- Lozoya M, Lozoya X. ... See full document

... extract against carbon tetrachloride-induced hepatic damage in experimental ...to carbon tetrachloride- treated mice significantly reduced the elevated serum levels ... See full document

... and antihepatotoxic properties of different concentrations of the extract against carbon tetrachloride (CCl4) which cause liver damage in rats are ...The antihepatotoxic ... See full document

... induced hepatic damage is due to generation of free radicals followed by lipid per oxidation and decreased activities of antioxidant enzyme levels (Aghel et ...resulting hepatic injury was ... See full document

... the hepatic cytochrome P-450-mediated formation of ...membrane against CCl4-induced damage under aerobic conditions but not under anaerobic conditions (Burk, ... See full document

... cytochrome p450 system to produce the trichloro methyl free radicals, (Akare SC, Sahare AY, 2009; Hanaa A Hassan et al., 2009) which in turn covalently binds to cell membranes and organelles to elicit lipid peroxidation. ... See full document

... Linn. against CCl 4 -induced hepatic damage in ...alcohol induced liver cell damage in nonhepatectomized and partially hepatectomized ... See full document

... www.wjpr.net 1391 observation of antitumor activity. The effect of Aloe vera on the growth of transplantable ascites tumor, body weight of EAC bearing hosts as well as alterations in the serum biochemical ... See full document

... Carboxymethylcellulose-sodium (CMC-Na) was purchased from Acros Organics (NJ, USA), liquid paraffin, carbon tetrachloride and heparin sodium were purchased from Merck (Dramstadt, Germany). Biochemical ... See full document

... Further evidence of antiyeast activity against C. albicans of the extract was obtained from SEM study (Figure 1). Figure 1 shows the SEM photomicrographs of the untreated and extract treated cells of C. ... See full document

... liver damage model. The activity was assessed by comparing the serum enzyme levels such as serum glutamate pyruvate transaminase, serum glutamate oxalate transaminase, total bilirubin, alkaline phosphatase ... See full document

... The results of phytochemical screening of the EECS revealed that presence of flavonoids and terpeniods. The terpenoids have been reported to protect lipids, blood and body fluids against the attack of reactive ... See full document

... In the present study SMD at both the doses has been found to reduce both serum ALP and bilirubin in the treated groups compared with the untreated ones. The site-specific oxidative damage of some of the ... See full document