[PDF] Top 20 An association between liraglutide treatment and reduction in excessive daytime sleepiness in obese subjects with type 2 diabetes

... the association between diabetes or insulin resistance and EDS was in- dependent of obesity [8, ...1055 subjects presenting for obesity surgery ...very obese (mean BMI, 38.1 kg/m ... See full document

... Excessive daytime sleepiness (EDS) is a common clinical ...a reduction of the quality of life, road accidents and workplace accidents [1, ...estimated between 10 and 20% in the general ... See full document

... for obese children, and a strong association emerged between BMI and sleep propensity (Fig ...and obese children prompted us to propose the existence of 2 types of clinical OSA, which ... See full document

... then liraglutide (and other incretin-based therapies) may be able to ameliorate the progressive deterioration in glycemic control, which, at present, seems an inescapable characteristic of ...in obese ... See full document

... reduce daytime sleepiness and instruct patients that adequate high-quality sleep is important to improve daytime ...to treatment for sleep disorders. Although persons with diabetes are ... See full document

... latency of 2.3–2.4 minutes at baseline, which was improved to .5 minutes (above the cutoff for pathological sleepiness) at the final visit in patients given armodafinil. This .3-minute increase in sleep latency ... See full document

... and diabetes mellitus have reached epidemic proportions globally [1–3] with approximately eighty percent (80%) of the populace with type 2 diabetes mellitus either obese or overweight ... See full document

... link between sleep disturbances and depression is however compli- ...the association between insomnia and depression in patients with ...associations between insomnia and depressive symptoms ... See full document

... of type 2 diabetes has been attributed to the classic triad of decreased insulin secretion, increased insulin resistance, and elevated hepatic glucose ...tract. Liraglutide is a modified form ... See full document

... associated. Excessive daytime sleepiness (EDS) is a common symptom of various types of sleep ...headache type, and the clinical characteristics of ...Epworth Sleepiness Scale (ESS) was ... See full document

... cessive daytime sleepiness (EDS) determined by daytime performance and cognition does not ...subjective sleepiness in mild to moder- ate OSAS, and the effects on objective sleepiness ... See full document

... EDS is also associated with increased risk of accidents when operating motor vehicles or other machinery. 13-15 The World Health Organization’s International Agency for Research on Cancer has classified sleep disturbing ... See full document

... and excessive daytime sleepiness affect cognitive ability and have a negative impact on the academic performance of medical ...of excessive daytime sleepiness, sleep quality and ... See full document

... were type 2 diabetes, obesity, snoring and uncon- trolled ...an association between snoring and EDS among hypertensive ...relationship between EDS and type 2 ... See full document

... outcomes as secondary outcomes, it was not powered for analyses of the individual renal out- comes. Also, patients were followed for 3.5 to 5.0 years, and thus we cannot extrapolate to longer-term effects. The trial ... See full document

... Excessive daytime sleepiness, decrease in school perfor- mance, abnormal daytime behavior, recent enuresis, morning headache, abnormal weight, and progressive devel- opment of hypertensi[r] ... See full document

... Headache and sleep complaints are prevalent in the general population and often coexist in the same subject [1]. Exces- sive daytime sleepiness (EDS) is associated with neuro- logical disorders and pain ... See full document

... of 2 double-blind parallel group studies conducted in patients with narcolepsy (n = 56) (Schwartz et al ...at 2-hour intervals from 9 am to 9 ...experience excessive sleepiness in the late ... See full document

... Of particular interest was the finding that persistent DRD was only associated with psychosocial rather than clinical variables in our study. These findings corroborated with previous studies which showed that ... See full document

... compared liraglutide in triple therapy, but studies that used liraglutide in dual therapy were reviewed in case NICE decided to approve it for such ... See full document