[PDF] Top 20 Biocompatible Nanocomplexes for Molecular Targeted MRI Contrast Agent
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Biocompatible Nanocomplexes for Molecular Targeted MRI Contrast Agent
... the contrast of the image because the contrast agent shortened relaxation ...low molecular weight contrast ...as molecular MRI contrast ...on molecular ... See full document
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Modular Synthesis of Targeted Molecular Imaging Agents for MRI, PET, and PET-MRI of Cancer
... improving molecular imaging methods is the use of targeted molecular imaging agents ...imaging agent to the cancerous cells, the imaging agent will collect more densely at the diseased ... See full document
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Original Article Gadopentetic acid-doped, multifunctional, potentially targeted mesoporous silica nanoparticles as a novel MRI nano-contrast agent: synthesis, characterization and MRI study
... the agent in the blood or target a specific location within the body ...excellent contrast agents and efficient drug carriers, and they can be designed as positive or negative imaging agents, or ...of ... See full document
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Design, synthesis, and evaluation of VEGFR-targeted macromolecular MRI contrast agent based on biotin–avidin-specific binding
... To link the antibodies to PDG, biotin–avidin reaction was employed in this study. Avidin is a kind of tetrameric glycoprotein with molecular weight of 60 kD. Avidin con- tains four identical subunits, each of ... See full document
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Ultrasound Molecular Imaging of the Breast Cancer Neovasculature using Engineered Fibronectin Scaffold Ligands: A Novel Class of Targeted Contrast Ultrasound Agent
... novel molecular imaging targets are being discovered and validated that may further improve diagnostic accuracy of USMI for better detection of various cancer types including breast cancer [9, 10, 52, 53], there ... See full document
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The Effectiveness of Ferritin as a Contrast Agent for Cell Tracking MRI in Mouse Cancer Models
... Molecular MRI includes cell targeting and tracking ...a targeted-probe to diagnose and treat tumors and inflammation, and the latter marks grafted cells so that their movement, proliferation, ... See full document
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<p>Single- and Multi-Arm Gadolinium MRI Contrast Agents for Targeted Imaging of Glioblastoma</p>
... The degree of Gd relaxivity is thought to depend on the distance between Gd-DOTA and the polyanion as a function of the length and degree of branching on linear and branched PEG. In NCA-Ab-Gd1 we placed one Gd complex at ... See full document
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Article SPIO-loaded nanostructured lipid carriers as liver targeted molecular T2-Weighted MRI contrast agent
... vivo [6]. There are two types of MRCAs: T1 and T2 MRCAs which affect the longitudinal and transverse relaxation times of water protons respectively. The typical examples of T1 MRCAs include gadolinium (Gd) complexes and ... See full document
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Biocompatible Polyhydroxyethylaspartamide based Micelles with Gadolinium for MRI Contrast Agents
... for MRI contrast ...controlled molecular weight can be excreted through kidney filtration after dissociation of the polymeric micelles into block copolymer ... See full document
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Magnetic Nanoparticles in Cancer Theranostics
... Direct injection of MNP into the tumour Although most commercially available products using nanoparticles are found as contrast agents, re- cently milestones have been reached regarding anti- cancer therapy. The ... See full document
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Synthesis of a gadolinium based-macrocyclic MRI contrast agent for effective cancer diagnosis
... University of Korea in accordance with the “Principles of Laboratory Animal Care”, NIH publication no. 85-23, re- vised in 1985. HCT 116 cells (1.0 × 10 6 cells) were sus- pended in 100 μl of phosphate buffer saline and ... See full document
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Self Assembled Superparamagnetic Iron Oxide Nanoclusters for Universal Cell Labeling and MRI
... as contrast agents for magnetic resonance imaging (MRI) and cell ...low molecular weight polyethylenimine (PEI) in an aqueous phase to form monodispersed nanocomposites with a controlled clustering ... See full document
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Water-soluble l-cysteine-coated FePt nanoparticles as dual MRI/CT imaging contrast agent for glioma
... dual MRI/CT contrast agent for malignant brain ...CT contrast imaging of FePt-Cys NPs was significantly more sensitive than that of the commonly used iohexol, even if the r 2 value of FePt-Cys ... See full document
9
Magnetic microbubble-mediated ultrasound-MRI registration based on robust optical flow model
... and MRI were carried out by active contour ...and MRI segmentation (reference image) was built, and the vector flow field was estimated by the Coarse-to-fine Gaussian pyramid (see Figure 2) and graduated ... See full document
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Potential and problems in ultrasound-responsive drug delivery systems
... surfactant-shelled Sonazoid had low fragmentation thresholds (mean 0.13 and 0.15 MPa at 1.1 MHz, and mean 0.48 and 0.58 MPa at 3.5 MHz, respectively), while polymer-shelled biSpheres had a significantly higher threshold ... See full document
13
Recent strategies to design vascular theranostic nanoparticles
... Restenosis mainly occurs due to remodeling of arterial wall through activation, proliferation and migration of vascular smooth muscle cells (VSMCs), and over production of extracellular matrix after balloon-angioplasty ... See full document
12
Biocompatible nanocomposite for PET/MRI hybrid imaging
... labeling agent (eg, a positron emitter), to allow multi-modal in vivo ...the targeted tumor lesions for early cancer diagnosis and treatment, the colloidal nanocarriers are required to be highly ... See full document
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A transferrin-target magnetic/fluorescent dual-mode probe significantly enhances the diagnosis of non-small cell lung cancer
... signal contrast between metastasis nodules and normal liver tissue appeared at 5 min and lasted to 24 ...signal contrast between metastasis nodules and normal liver tissue demonstrates that the probe ... See full document
13
Targeted delivery of reduced graphene oxide nanosheets using multifunctional ultrasound nanobubbles for visualization and enhanced photothermal therapy
... kDa molecular weight cutoff (MWCO) filter to completely remove any unconjugated PEG (10 ...microscopy, targeted NBs-gPc3-rgO were clustered on the surface of the hep g2 cells (H and I, 4,000× and 10,000×, ... See full document
14
Fe3O4@Ag Nanoprobe for Detection of Ovarian Cancer Cell Line Using Magnetic Resonance Imaging
... designed, synthesized, and characterized by FTIR, DLS and SEM. The results revealed that the nanoparticles are negatively- charged 100 nm spheres. Theoretically, these specifications make it suitable for diagnosing ... See full document
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