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[PDF] Top 20 Biology of RANK, RANKL, and osteoprotegerin

Has 10000 "Biology of RANK, RANKL, and osteoprotegerin" found on our website. Below are the top 20 most common "Biology of RANK, RANKL, and osteoprotegerin".

Biology of RANK, RANKL, and osteoprotegerin

Biology of RANK, RANKL, and osteoprotegerin

... However, RANKL does not induce OCP mobilization in protein tyrosine phosphatase- ε knockout mice with osteoclasts that are defective in terms of bone adhesion and resorption ...Thus, RANKL-induced ... See full document

7

Original Article Expression of osteoprotegerin, RNAK and RANKL genes in femoral head avascular necrosis and related signaling pathway

Original Article Expression of osteoprotegerin, RNAK and RANKL genes in femoral head avascular necrosis and related signaling pathway

... challenge. Osteoprotegerin (OPG), receptor activator of nuclear factor κB (RANK) and its ligand (RANKL) all regulate the formation of bones via gene transcriptional regulation for the balance between ... See full document

8

Osteoprotegerin inhibits bone resorption and prevents tumor
development in a xenogenic model of Ewing's sarcoma by
inhibiting RANKL

Osteoprotegerin inhibits bone resorption and prevents tumor development in a xenogenic model of Ewing's sarcoma by inhibiting RANKL

... triad osteoprotegerin (OPG)/receptor activator of NF-kB (RANK)/RANK Ligand (RANKL) is strongly implicated ...by RANKL, a cytokine member of the tumor necrosis factor (TNF) superfamily ... See full document

10

Effects of pamidronate disodium on the loss of osteoarthritic subchondral bone and the expression of cartilaginous and subchondral osteoprotegerin and RANKL in rabbits

Effects of pamidronate disodium on the loss of osteoarthritic subchondral bone and the expression of cartilaginous and subchondral osteoprotegerin and RANKL in rabbits

... of osteoprotegerin/ receptor activator of nuclear factor-κ B/RANK ligand (OPG/RANK/RANKL) has been described as critical in controlling osteoclast ...biology. RANKL, synthesized ... See full document

12

Anti CD11b antibody treatment suppresses the osteoclast generation, inflammatory cell infiltration, and autoantibody production in arthritis prone FcγRIIB deficient mice

Anti CD11b antibody treatment suppresses the osteoclast generation, inflammatory cell infiltration, and autoantibody production in arthritis prone FcγRIIB deficient mice

... ligand RANKL expressed on synovial fibroblasts, osteo- blasts, and T helper 17 (Th17) cells ...The RANKL- mediated osteoclastogenesis is counterbalanced by the physiologically expressed decoy receptor, ... See full document

11

Emerging treatments for postmenopausal osteoporosis – focus on denosumab

Emerging treatments for postmenopausal osteoporosis – focus on denosumab

... (RANKL), RANK and osteoprotegerin (OPG) plays a central role in coupling bone formation and resorp- tion during normal bone turnover and in a wide spectrum of diseases characterized by disturbed bone ... See full document

10

Porphyromonas gingivalis infection increases osteoclastic bone resorption and osteoblastic bone formation in a periodontitis mouse model

Porphyromonas gingivalis infection increases osteoclastic bone resorption and osteoblastic bone formation in a periodontitis mouse model

... Lipopolysaccharides; RANKL: Receptor activator of nuclear factor-kappaB ligand; OPG: Osteoprotegerin; TSBY: Trypticase Soy Broth supplemented with yeast extract; BAP: Blood agar plates; PBS: Phosphate ... See full document

9

Type 2 diabetes affects bone cells precursors and bone turnover

Type 2 diabetes affects bone cells precursors and bone turnover

... (RANKL), Osteoprotegerin (OPG), Sclerostin (SCL) and Dickoppf-1 (DKK-1) as cytokines involved in the control of osteoblast and osteoclast formation and activity, bone density (BMD) and quality trough ... See full document

8

Bone loss: Factors that regulate osteoclast differentiation   an update

Bone loss: Factors that regulate osteoclast differentiation an update

... cytokine, osteoprotegerin ligand) have emphasized the crucial role of RANKL, which is expressed by osteoblast/stromal cells, and its receptor RANK, which is expressed by osteoclast cells, in osteo- ... See full document

6

RANK/RANKL/OPG system in the intervertebral disc

RANK/RANKL/OPG system in the intervertebral disc

... OPG: Osteoprotegerin; PCR: Polymerase chain reaction; RANK: Receptor activator of nuclear factor kappa B; RANKL: Receptor activator of nuclear factor kappa B ligand; rhIL-1 β : Recombinant human IL-1 ... See full document

10

Dysregulation of the RANKL/RANK/OPG axis in thalassemia intermedia patients

Dysregulation of the RANKL/RANK/OPG axis in thalassemia intermedia patients

... (RANK)/ osteoprotegerin (OPG) axis plays an important role in metabolic bone ...the RANKL/RANK/OPG axis and the bone-turnover markers CTX and P1NP in ... See full document

5

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines

... are RANK-positive, as revealed by immunohis- tochemistry ...of RANKL by recombinant osteoprotegerin, a decoy receptor for RANKL, suppressed tumor bone me- tastasis and progression and improved ... See full document

9

Impact of Smoking on the IL-1Β, IL-8, IL-10, IL-17 and TNF-α Production in Chronic Periodontitis Patients

Impact of Smoking on the IL-1Β, IL-8, IL-10, IL-17 and TNF-α Production in Chronic Periodontitis Patients

... Interleukin-17, rankl, osteoprotegerin levels in gingival crevicular fluid from smoker versus non-smoker chronic periodontitis patients during initial periodontal treatme[r] ... See full document

9

RANK ligand (RANKL) expression in young breast cancer patients and during pregnancy

RANK ligand (RANKL) expression in young breast cancer patients and during pregnancy

... of RANKL as a potential target in breast cancer arising in young ...the biology of tumors aris- ing in young women (D-BEYOND; ...express RANKL, raising the question of whether it could serve as a ... See full document

9

Anti-RANKL therapy for bone tumours: Basic, pre-clinical and clinical evidences

Anti-RANKL therapy for bone tumours: Basic, pre-clinical and clinical evidences

... [25]. RANKL transgenic mice and RANKL knockout mice are respectively osteoporotic and osteopetrotic ...soluble RANKL produced by osteoblasts interact with RANK expressed on monocyte lineage ... See full document

10

RANK-RANKL signalling in cancers

RANK-RANKL signalling in cancers

... 40. Hsu, H., Lacey, D.L., Dunstan, C.R., Solovyev, I., Colombero, A., Timms, E., Tan, H.L., Elliott, G., Kelley, M.J., Sarosi, I., Wang, L., Xia, X.Z., Elliott, R., Chiu, L., Black, T., Scully, S., Capparelli, C., ... See full document

50

NF κB p100 limits TNF induced bone resorption in mice by a TRAF3 dependent mechanism

NF κB p100 limits TNF induced bone resorption in mice by a TRAF3 dependent mechanism

... PBS, RANKL, or TNF to prevent the synthesis of new protein and thus observe degradation of TRAF3 by Western ...blot. RANKL accelerated the degradation of TRAF3, starting at 1 hour and continuing through 4 ... See full document

12

IL-6, IL-1β, and TNF-α only in combination influence the osteoporotic phenotype in Crohn’s patients via bone formation and bone resorption

IL-6, IL-1β, and TNF-α only in combination influence the osteoporotic phenotype in Crohn’s patients via bone formation and bone resorption

... In the present study, we demonstrated that the combina- tion of the 3 cytokines IL-6, IL-1β, and TNF-α increased the RANKL/OPG ratio in an osteoblast cell model, sug- gesting an indirect effect of cytokines on  ... See full document

12

RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells

RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells

... OPG, RANKL, collagen I (Coll I), osteocalcin (OC), Bone Sialo-Protein (BSP), bone morphogenetic protein-2 (BMP-2), core binding factor 1 (Cbfa1), RANK, calcitonin receptor (CTR), tartrate resistant acid ... See full document

9

Understanding how ESOL Pre Services Teachers' Prior Experiences and Background Shape their Processes of becoming L2 (Reading) Teachers

Understanding how ESOL Pre Services Teachers' Prior Experiences and Background Shape their Processes of becoming L2 (Reading) Teachers

... paracrine RANKL-RANK signaling could be responsible for driving prostate cancer bone metastasis by promoting epithelial to mesenchymal transition ...converging RANKL-c-Met signaling network in which ... See full document

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