[PDF] Top 20 Caffeine Ameliorating Effect on Anxiety and Depression in an Aluminum Chloride-induced Alzheimer's Disease Rat Mode

... of anxiety including measuring the time spent for freezing (immobility), exploratory behaviours in the form of ambulation (horizontal locomotion) and rearing (vertical activity) as well as non-exploratory measures ... See full document

... in Alzheimer Disease patients and Alzheimer Disease animals ...Aluminium Chloride (AlCl 3 ), when administered, cause memory dysfunction through combined actions of brain ... See full document

... Alzheimer’s disease is recognized as the most prevalent form of ...AD, induced in ...mg/kg/day aluminum chloride for 4 ...Results: Aluminum chloride injection in rats ... See full document

... progressively, locomotor impairment, and the biochemical changes as resembles AD in human [22]. Even after extensive study, the exact pathological mechanism of AD was not clear, and it was assumed that the oxidative ... See full document

... From this study, it could be concluded that the raisin had a neuroprotective effect on rats with AD. It prevented LPO arising, increased GSH, GSSG, and SOD levels in the brain, and improved memory and learning in ... See full document

... We confirmed that the ADAS-Cog instrument is not sensitive to detect change over time at pre-dementia stages of the disease such as MCI (as shown by small SNRs), and therefore the impact of enrichment strategies ... See full document

... planet. Caffeine has surely understood here and now fortifying consequences for focal sensory system, however the long haul affect on insight have been less ...evident. Caffeine expands readiness and ... See full document

... vascular disease, n = 3 Lewy body disease, n = 2 traumatic brain injury, n = 1 neoplasm, n = 1 normal pressure hydrocephalus, n = 3 depression, n = 3 other psychiatric disease, n = 4 medical ... See full document

... Additional file 2: Table S2 shows baseline characteris- tics by age categories and sex. All cardiovascular risk factors except diabetes were more frequent in men than in women, as well as with increasing age. ... See full document

... i s , the acetylcholine receptor), while potassium chloride did ...direct effect on the SR (Moulds, ...and caffeine were not affected by the electrical stabilization of the sarcolemma by ... See full document

... For comparison of demographic and clinical variables be- tween groups with and without progression to dementia, we used the Pearson chi-squared test, Mann–Whitney test, or Student’s t test as appropriate. We assessed the ... See full document

... The precise mechanism by which aromatherapy may ameliorate the side effects of chemotherapeutic treatment is unclear. Some studies suggest that essential oils may exert positive influences on patient’s well-being on ... See full document

... suppressive effect of these compounds on AchE appears to be associated with the presence of either free hydroxyl group or keto group at C-11 and the presence of free hydroxyl group at C-3 in the ursane skeleton ... See full document

... AD: Alzheimer ’ s disease; ADCS-ADL: Alzheimer ’ s Disease Cooperative Study/ Activities of Daily Living Inventory; ADCS-MCI-ADL-18: 18-item Alzheimer ’ s ... See full document

... Inherited Alzheimer Network (DIAN) is an international registry of individuals at risk for developing autosomal dominant Alzheimer ’ s disease ... See full document

... mild Alzheimer ’ s dementia patients, first-degree relatives of patients with Alzheimer ’ s dementia, and cognitively unimpaired control subjects are ... See full document

... The problem is not limited only to the patient's loss of independence, but also has repercussions on the relatives. In fact, the progressive cognitive deterioration as well as patient's loss of physical capabilities, ... See full document

... The study protocol was approved by the ethics commit- tee of the university clinic Erlangen-Nürnberg (number 3987), and all participants provided written informed consent. The patients were recruited in the memory clinic ... See full document

... mean effect size between the two samples was large for anxiety and depression (respectively, d = ...mean effect size between the two samples was large both for anxiety and ... See full document

... Several other endeavors have been undertaken to de- sign and validate composite measures that are more ap- propriate to assess changes earlier clinical stages of AD. These composites range from purely statistically ... See full document