[PDF] Top 20 Cancer Progression Related with Tumor associated Macrophages
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Cancer Progression Related with Tumor associated Macrophages
... of macrophages, mimic the Th1–Th2 activation of T cells, denote two opposite functional state of ...M2 macrophages are known as resting phenotype which promotes healing-type situations without infections ... See full document
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Elevated expression of Tiam1 is associated with poor prognosis and promotes tumor progression in pancreatic cancer
... primary tumor or metastatic tumor tissues according to Oncomine data ...pancreatic cancer cell lines as ...pancreatic cancer cells; a nuclear staining pattern was also ... See full document
9
Pattern of expression of immune- and stroma-associated genes in blood of mice with experimental B16 melanoma
... by tumor-associated macrophages [34] and promotes migration of cancerous cells through the CCL22-CCR4 axis [35, ...of tumor-associa ted macrophages, CD68, showed more than 3-folds ... See full document
7
“Role of Inflammatory Markers in Tumorogenesis” by Suganya V, Anuradha V, India.
... changes. Tumor enlargement is stimulated by the survival and clonal expansion of these “initiated” ...cells. Progression includes a generous development in tumor dimension and either growth- ... See full document
10
TGF- Sustains Tumor Progression Through
... cells like cancer associated fibroblasts to inhibit tumor progression and metastasis at early stages of 53.. disease ( 13 ).[r] ... See full document
17
Lactate inhibits ATP6V0d2 expression in tumor associated macrophages to promote HIF 2α–mediated tumor progression
... Macrophages are influenced by the local environment as sentinels of the immune system and acquire additional activities tailored for their tissue-specific functions (23). mTOR signaling senses and integrates ... See full document
17
High tumor-associated macrophages infiltration is associated with poor prognosis and may contribute to the phenomenon of epithelial–mesenchymal transition in gastric cancer
... The indicator expression was evaluated, respectively, by two pathologists who were blinded to the clinical data. The staining results of three indicators were scored semi- quantitatively on the basis of immunostaining ... See full document
9
Interleukin-32θ inhibits tumor-promoting effects of macrophage-secreted CCL18 in breast cancer
... negative related breast cancer ...breast cancer cells with triple negative background [33], together with PMA-treated THP-1 macrophage cells to mimic the interaction be- tween macrophages and ... See full document
14
Elevated CD163+/CD68+ Ratio at Tumor Invasive Front is Closely Associated with Aggressive Phenotype and Poor Prognosis in Colorectal Cancer
... M2 macrophages, making this protein unspecific to the M2 macrophages correlated with tumor growth ...Second, macrophages are distributed in the different microanatomical locations of CRC ... See full document
15
Tumor associated macrophages in breast cancer: distinct subsets, distinct functions
... mammary tumor virus promoter, spontaneously develop mammary tumors in stages comparable to the human ...Mammary tumor progression in this MMTV-PyMT model is altered in a M-CSF null background, with ... See full document
8
The impact of hypoxia on tumor associated macrophages
... entrapped, macrophages are primed to serve protumor- al functions (Figure ...hypoxic tumor regions by genetically targeting Nrp1 prevents angiogenesis and cancer immune escape, providing evidence ... See full document
9
Targeting microRNAs as key modulators of tumor immune response
... are associated with several human pathologies, including cancer in all its stages ...a tumor sup- pressor role ...proteins related to miRNA biogen- esis, with poor outcome ...between ... See full document
19
Targeting tumor associated macrophages as a novel strategy against breast cancer
... stimulate tumor angiogenesis and tumor growth and ...and tumor tissue cells were collected from vaccinated mice and from suit- able control ...isolated tumor cells were cultured and their ... See full document
11
Heme oxygenase-1: emerging target of cancer therapy
... the cancer cells of prostate, lung, and oral cancer tissues, and associated with tumor progression ...lung cancer cells, and cor- relates with HO-1 nuclear localization in the ... See full document
7
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
... addition, tumor graft models showed that CSF-1 depletion led to greatly reduced macrophage density, delayed tumor progression, and se- verely inhibited metastasis [22, 24, 42, ...both tumor ... See full document
16
Tumor-associated macrophages: an accomplice in solid tumor progression
... primary tumor to create a metastatic colony ...of tumor cells depends on the ...in cancer me- tastasis. TAMs primarily facilitate tumor cell invasion and migration by secreting matrix ... See full document
13
<p>Tumor-Associated Macrophages (TAMs): A Critical Activator In Ovarian Cancer Metastasis</p>
... promoting tumor establishment process. As we all know, tumor growth depends on the formation of new blood ...ovarian cancer cells reach a certain size, diffusion alone cannot supply enough nutri- ... See full document
13
Tumor-associated macrophages, potential targets for cancer treatment
... Activation of the nuclear factor κB pathway also plays an important role in polarization of TAMs to an antitumor phenotype using Toll-like receptor agonists, anti-CD40 mAbs and IL-10 mAbs [22]. In addition, regulation of ... See full document
6
Legumain Promotes Gastric Cancer Progression Through Tumor-associated Macrophages In vitro and In vivo
... (PMA/IL-4/IL-13) with or without LGMN KD were subcutaneously transplanted into the right flank of nude mice (n=6 in each group, 4 to 6 weeks old, male, purchased from the Department of Experimental Animal Science, ... See full document
9
Targeting tumor-associated macrophages to combat pancreatic cancer
... The tumor microenvironment is replete with cells that evolve with and provide support to tumor cells during the transition to ...pancreatic tumor microenvironment is suggested to contribute to the ... See full document
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