[PDF] Top 20 ANTI-CATATONIC ACTIVITY OF SOME NOVEL SERIES OF NSUBSTITUTED-6-METHYL-N-5-SUBSTITUTED, 1, 5-DIHYDRO-4HPYRAZALO (3, 4-d)-PYRIMIDINE-4(5H)-ONE
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ANTI-CATATONIC ACTIVITY OF SOME NOVEL SERIES OF NSUBSTITUTED-6-METHYL-N-5-SUBSTITUTED, 1, 5-DIHYDRO-4HPYRAZALO (3, 4-d)-PYRIMIDINE-4(5H)-ONE
... represent one of the most active classes of compounds possessing a wide spectrum of biological activities ...depressant activity, Anti-inflammatory activity(3),Ca ++ blocking ... See full document
6
EVALUATION OF SUBSTITUTED PYRIMIDINE HYBRIDS FOR ANTIBACTERIAL AND ANTI FUNGAL ACTIVITY: FACILE SYNTHESES UNDER CATALYSIS BY IONIC LIQUID
... of substituted 1-(1-(6-methyl-2-oxo-4-phenyl-1,2,3,4- tetrahydropyrimidin-5- yl)ethylidene)thiosemicarbazide are carried out by refluxing ... See full document
9
IN VITRO ANTIOXIDANT ACTIVITY OF NOVEL 4-HYDROXY-1-METHYL-3-(3-SUBSTITUTED)-4,5-DIHYDROISOXAZOL-5-YL)QUINOLIN-2(1H)-ONE DERIVATIVES
... antituberculosis 3 anti- inflammatory 4 , anti-viral 5 ,analgesic 6 ,antitumor 7 , chemotherapy, antinociceptive 8 , macrophage migration inhibitory factor activity, ... See full document
6
Synthesis and antimicrobial activity of some ethyl [6 methyl 2 methoxy 3 (substituted phenylethanone) 4 (substituted phenyl)] 1,2,3,4 tetrahydropyrimidine 5 carboxylates
... including anti tumor [4], anti- inflammatory [5] and antibacterial [6] activities has been ascribed to these partly reduced pyrimidine ...antihypertensive activity of ... See full document
11
Synthesis, Spectral, Theoretical, Antimicrobial Evaluation, and Molecular Docking Studies of Some Novel Ethyl 5 (1 Methyl 1h Tetrazol 5 Ylthio) 4 Oxo 2,6 Substituted Diphenylpiperidine 3 Carboxylate Derivatives
... A series of novel ethyl 5-(1-methyl-1H-tetrazol-5-ylthio)-4-oxo-2,6-substituted diphenylpiperidine-3-carboxylate derivatives (1-9) were synthesized in ... See full document
15
Novel Ethyl 2 (1 aminocyclobutyl) 5 (benzoyloxy) 6 hydroxy pyrimidine 4 carboxylate Derivatives: Synthesis and Anticancer Activities
... anticancer activity of 2, 4, 5, 6-substituted pyrimidines, several ethyl 2-(1-aminocyclobutyl)-5-(benzoy- loxy)-6-hydroxy-pyrimidine-4-carboxylate ... See full document
8
Preparation and Biological Evaluation of 3-amino-4-aryl-4, 5- dihydro-1-N-tolyl pyrazolo [3, 4-d] pyrimidines Derivative
... antibacterial activity towards Gram positive and Gram negative bacterial strain and antifungal activity towards Aspergillus nigor and Candida albicans at different concentration for their MIC ... See full document
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Three Component Condensation: Synthesis and Chracterization of Bioactive 4-Substituted Aryl Pyrimidinones and Pyrimidinethiones
... antitumor, anti-inflammatory, antihypertensive, antiviral , antibacterial, fungicidal, as calcium channel blockers and as potent inhibitor of cancer cell profilation 3-12 ... See full document
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Synthesis and anti inflammatory activity of some [4, 6 (4 substituted aryl) 2 oxo 1, 2, 3, 4 tetrahydropyrimidin 5 yl] acetic acid derivatives
... Synthesis of Succinic Anhydride (I)[5] In a 500 ml RBF, provided with a reflux condenser protected by a calcium chloride drying tube, placed 29.50 gm (0.25 mol) of Succinic acid and 51 gm (47.25 ml, 0.5 mol) of ... See full document
8
MICROWAVE ASSISTED SYNTHESIS OF SOME NEW THIAZOLIDIN 4 ONE DERIVATIVES CONTAINING A PYRIMIDONE AND QUINOLINE MOITIES
... I have synthesized new thiazolidene derivatives from pyrimidine and quinolene derivatives. The mixture of aldehydes, ethyl acetoacetate and urea/ thiourea gives the compound ... See full document
9
Novel Synthesis, Characterization of some New Substituted Coumarin and Schiff Base, Substituted benzo-coumarin and benzo-Schiff Base and Study of their Antibacterial Activities
... To the primary amine (1a,2a;0.025 mole), diethyl malonate (0.05 mole) was added in the presence of a catalyst (DMF), refluxed for 45 - 60 minutes, cooling, filtered. Take solid part of (1a) and recrystallized by absolute ... See full document
6
Methyl 4 (4 fluorophenyl) 6 isopropyl 2 (methylsulfonyl)pyrimidine 5 carboxylate
... (Fig. 1) contains three independent ...(N3/N4/C20-C23), D (C27-C32), E (N5/N6/C36-C9) and F (C43-C48) are, of course, planar, and the dihedral angles between them are A/B = ...and D/E = ...(Table ... See full document
15
ANTI-ANXIETY, ANTI-DEPRESSANT AND ANTI- CATALEPTIC ACTIVITY OF 4-HYDROXY-3-[2-(3-NITROPHENYL)-2, 3-DIHYDRO-1, 5- BENZOTHIAZEPIN-4-YL]-2H-CHROMEN-2-ONE
... (1, 3) is the most common of the affective disorders; it may range from a very mild condition, bordering on normality, to severe (psychotic) depression accompanied by hallucinations and ... See full document
9
Methyl 5 (4 acetoxyphenyl) 2 (2 bromobenzylidine) 7 methyl 3 oxo 2,3 dihydro 5H 1,3 thiazolo[3,2 a]pyrimidine 6 carboxylate
... Fig. 1. The 4-acetoxy substituted benzene ring is axially substituted to the pyrimidine ...central pyrimidine ring adopts a half chair conformation with deviations of ... See full document
9
1,4 Dihydro 6 methyl 5 (N methylcarbamoyl) 4 (4 nitrophenyl)pyrimidine 2(3H) thione monohydrate
... S1 0.0707 (4) 0.0556 (3) 0.0343 (3) −0.0093 (3) −0.0041 (2) −0.0043 (2) O1 0.186 (3) 0.141 (2) 0.0876 (17) 0.077 (2) −0.0173 (17) −0.0592 (16) O2 0.0750 (12) 0.0633 (11) 0.1208 (17) ... See full document
8
5��4���D�6� 5��� ������6� 5� ����6�
... Percentage of individuals finding the pre-specified pages.. immediately or somewhat immediately.[r] ... See full document
6
4 (4 Bromophenylhydrazono) 1 (5 bromopyrimidin 2 yl) 3 methyl 2 pyrazolin 5 one
... C41B 0.025 (3) 0.027 (3) 0.022 (3) −0.003 (2) 0.000 (2) −0.007 (2) C42B 0.038 (3) 0.031 (3) 0.028 (3) 0.000 (3) −0.011 (3) −0.003 (2) C43B 0.037 (3) 0.028 ... See full document
13
Synthesis, characterization and pharmacological studies of some novel 2 N (aryl substituted) 4 methyl 6 phenylpyrimidine 5 carboxylic acids
... To a solution of 3(3.61 mmol) and substituted aniline(4.33 mmol) in 1,4-dioxane(25 mL), 4.0M HCl in 1,4- dioxane(2 mL) was added and was heated at 100 o C for 12 h. Progress of the reaction was monitored by ... See full document
5
SYNTHESIS, CHARECTERIZATION AND ANTIMICROBIAL ACTIVITY OF 5 METHYL 2, 4 DIHYDRO 3H PYRAZOL 3 ONE 4 (4 SUBTITUTED) BENZYLPIPERAZINE DERIVATIVES
... Chemistry: Melting points were determined using Thermonik Melting Point Apparatus (Campbell electronics, India) by capillary method and are uncorrected. Infrared (IR) spectra were taken on a Fourier Transform Infrared ... See full document
5
5 Anilino 3 benzylsulfanyl 6 (3 chloroanilino) 1 phenyl 1H pyrazolo[3,4 d]pyrimidin 4(5H) one
... To a solution of iminophosphorane (2 mmol) in dry dichloromethane (20 ml) aryl isocyanate(2 mmol) was added under nitrogen atmosphere at room temperature. After the reaction mixture was stirred for 1.5 h, 0.231 g (2.0 ... See full document
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