[PDF] Top 20 Characterization of Occult Hepatitis B Virus Infection from Blood Donors in China

... The function of X protein could be influenced by the dele- tion, insertion, and substitutions of core regulatory elements (Table 4) because the X gene overlaps with the enhancer and core promoter regions. Two important ... See full document

... Huai’an, China, and written informed consent was obtained from each participant (Ethics Certification Number: ...chronic hepatitis B (CHB), and 119 OBI patients were recruited from ... See full document

... Recently, several studies investigating the prevalence of OBI among blood donors from various regions of the world demonstrated that 0 to 2.87 % of the donors had OBI (reviewed by Assar et ... See full document

... Hepatitis B virus (HBV) is an enveloped dou- ble-stranded DNA virus in Hepadnaviridea family that causes acute and chronic hepatitis in humans ...with Hepatitis B and 350 ... See full document

... Huang et al, carried out the molecular characterization of HBV from OBI cases in a cohort of blood donors (n = 38.499). The analysis of the ORF S showed a higher frequency of mutations in MHR ... See full document

... for hepatitis B virus (HBV) surface antigen (HBsAg) has reduced the risk of overt HBV transfusion-transmitted infections (TTIs), although transfu- sion-transmitted infections continue to ... See full document

... appropriate blood donor pool size [20,21]. We screened 11 reactive samples from 120 blood donors using ...in China. We found that the test results from NAT were almost perfectly ... See full document

... of infection (negative for HBsAg, anti-HBc, and ...that occult HBV can occur either in patients with serological evidence of past “apparently resolved” HBV infection, or also in indi- viduals with no ... See full document

... derived from the regions coding for HBsAg, hepatitis B core anti- gen (HBcAg) and pre-C respectively as previously reported with minor modifications ...Dalian, China) and 5 μl DNA tem- ... See full document

... HBV infection [11, ...HBV infection such as susceptibility, persistent infection, and disease progression [6]; however, to date, the effect of HLA-DP variants on OBI detection has not been ... See full document

... A nested PCR was performed in order to amplify the overlapping surface/polymerase gene covering nucleo- tides 403–768 from the EcoR1 site using primers and protocols described previously [14]. This generates a 366 ... See full document

... Blood donors, who are volunteers for blood donation, are usually considered as a healthier part of public ...the blood banks in public and private hospitals have standard selection criteria ... See full document

... Central China, a car city named Shiyan, which is also the water source of the Middle Route Project for South to North Water Transfer, has 3 million popula- tions including 1 million permanent resident populations ... See full document

... C virus (HCV) is a serious global public health problem is one of the most frequent infections associated with blood transfusion ...Non B (NANB) transfusion-related hepatitis ...HCV ... See full document

... occur from apparently healthy blood ...the occult HBV infections ...of hepatitis B virus infection in the population and the sensitivity of la- boratory methods could ... See full document

... In Mexico, cirrhosis has shown an increasing ten- dency, rising from 12,058 cases in 2005 to 12,996 cases in 2006. In addition, cirrhosis is the second cause of death in the 15- to 64-year-old age group, being ... See full document

... of hepatitis B core antibodies as a marker of previous HBV infection in the two groups of patients, as well as possible correla- tion with certain parameters, including age, gender, liver enzymes, ... See full document

... livers from donors with OHB carry a risk of HBV transmission with infection occurring in 25–95 % of the liver grafts donated from patients who are HBsAg negative but anti-HBc positive ...(23). ... See full document

... the hepatitis C virus (HCV) is important for designing therapeutic strategies and regional specific diagnostic ...infected blood donors. This is the first report on HCV genotypes in ... See full document

... Results: HBV coinfections were found in 12.9% (79/614) HIV infected individuals including 42/417(10.1%) blood donors and 37/197 (18.8%) AIDS patients. In the HBsAg positive individuals, 80.0% were HBeAg ... See full document