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[PDF] Top 20 Choosing a control intervention for a randomised clinical trial

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Choosing a control intervention for a randomised clinical trial

Choosing a control intervention for a randomised clinical trial

... of clinical equipoise for the conduct of a RCT, Freedman [2] also emphasized the need for designing and conducting the trial in a manner that ensures that equipoise will be disturbed if one of the com- ... See full document

5

Study protocol for a randomised controlled trial  assessing the clinical and cost effectiveness of the Journeying through Dementia (JtD) intervention compared to usual care

Study protocol for a randomised controlled trial assessing the clinical and cost effectiveness of the Journeying through Dementia (JtD) intervention compared to usual care

... the trial, they will be ...the trial, but indi- cates they wish to remain in the study, the consultee will be asked to make a judgement, based on their existing and pre-existing knowledge of the person with ... See full document

13

Targeted Adherence Intervention to Reach Glycemic Control with Insulin Therapy for patients with Diabetes (TARGIT-Diabetes): rationale and design of a pragmatic randomised clinical trial

Targeted Adherence Intervention to Reach Glycemic Control with Insulin Therapy for patients with Diabetes (TARGIT-Diabetes): rationale and design of a pragmatic randomised clinical trial

... multifaceted intervention in each of the three study arms is an individually tailored telephone consultation conducted by a clinical pharma- ...the intervention (see figure 1) and the frequency of ... See full document

7

A three month controlled intervention of intermittent whole body vibration designed to improve functional ability and attenuate bone loss in patients with rheumatoid arthritis

A three month controlled intervention of intermittent whole body vibration designed to improve functional ability and attenuate bone loss in patients with rheumatoid arthritis

... semi randomised controlled clinical trial to assess the impact of a WBV intervention aiming to improve functional ability, attenuate bone loss, and improve habitual physical activity levels in ... See full document

7

A randomised controlled demonstration trial of multifaceted nutritional intervention and or probiotics: the healthy mums and babies (HUMBA) trial

A randomised controlled demonstration trial of multifaceted nutritional intervention and or probiotics: the healthy mums and babies (HUMBA) trial

... Maternal and neonatal outcomes are collected within 72 h of birth by a research midwife. Infants are weighed at birth (Mobile electronic baby scales, SECA 334, Germany) and detailed anthropometric measurements obtained ... See full document

12

A randomised, controlled trial of the effects of a mobile telehealth intervention on clinical and patient-reported outcomes in people with poorly controlled diabetes

A randomised, controlled trial of the effects of a mobile telehealth intervention on clinical and patient-reported outcomes in people with poorly controlled diabetes

... Similar to another study,[28] MTH was not found to influence the number of DOAs attended at the clinic. Studies on TH for diabetes have often focused on measures of hospitalisation or inpatient stays.[51–53] Fewer ... See full document

18

Prehospital randomised assessment of a mechanical compression device in cardiac arrest (PaRAMeDIC) trial protocol

Prehospital randomised assessment of a mechanical compression device in cardiac arrest (PaRAMeDIC) trial protocol

... tions. Control room personnel will be blinded to the allo- cation of the ambulance service vehicles, to ensure that there is no bias in whether a LUCAS or control trial vehi- cle is sent to an ... See full document

9

Acupuncture as a complex intervention for depression: A consensus method to develop a standardised treatment protocol for a randomised controlled trial

Acupuncture as a complex intervention for depression: A consensus method to develop a standardised treatment protocol for a randomised controlled trial

... case-based clinical experiences along with small and poorly conducted ...develop clinical guidelines in conventional medical contexts where the literature-based evidence is ... See full document

27

Implementation and effectiveness of 'care navigation', coordinated management for people with complex chronic illness: rationale and methods of a randomised controlled trial

Implementation and effectiveness of 'care navigation', coordinated management for people with complex chronic illness: rationale and methods of a randomised controlled trial

... c) clinical staff with daily indirect involvement with CN to provide broader organizational context; and d) patients in the intervention arm, focusing on their experience of chronic illness and its ... See full document

6

Effectiveness of an internet delivered intervention for generalized anxiety disorder in routine care: A randomised controlled trial in a student population

Effectiveness of an internet delivered intervention for generalized anxiety disorder in routine care: A randomised controlled trial in a student population

... Richards et al. (2015a) conducted a systematic review and meta- analysis of internet-delivered psychological interventions for the treatment of GAD. Studies recruited primarily through websites and/ or adverts in local ... See full document

9

Maternal low glycaemic index diet, fat intake and postprandial glucose influences neonatal adiposity – secondary analysis from the ROLO study

Maternal low glycaemic index diet, fat intake and postprandial glucose influences neonatal adiposity – secondary analysis from the ROLO study

... control trial of 800 secundigravida women with a previous macrosomic baby (>4 kg) randomised to receive low gly- caemic index (GI) dietary advice versus usual care (no dietary advice) to reduce ... See full document

12

A pragmatic randomized controlled trial of a guided self help intervention versus a waiting list control in a routine primary care mental health service

A pragmatic randomized controlled trial of a guided self help intervention versus a waiting list control in a routine primary care mental health service

... to Psychological Therapies (IAPT) services, which has received significant investment (Department of Health, 2007). Low intensity interventions are provided by workers such as primary care graduate mental health workers ... See full document

25

Cluster randomised trials with repeated cross sections: some alternatives to parallel group designs

Cluster randomised trials with repeated cross sections: some alternatives to parallel group designs

... (allowing intervention clusters to be compared not only with parallel controls but also with themselves under an earlier control condition) need fewer clusters than a trial with a single cross ... See full document

6

Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients

Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients

... We conducted this trial with frontline ICU PTs that included study participants as part of their clinical case- load. PT capacity was a barrier for enrolment due to unexpected staffing shortages and limited ... See full document

9

A RANDOMISED CONTROL CLINICAL TRIAL OF SHIVPALPINDI IN THE MANAGEMENT OF AMLAPITTA     .......

A RANDOMISED CONTROL CLINICAL TRIAL OF SHIVPALPINDI IN THE MANAGEMENT OF AMLAPITTA .......

... Samprapti Vighatana by the trial drug:- The samprapti of Amlapitta starts from increased jaleeyaamsha of Pachaka pit- ta,leading to Agnimandya. This preparation contains the drugs which are either pittaka- ... See full document

13

Results of a feasibility cluster randomised controlled trial of a peer-led school-based intervention to increase the physical activity of adolescent girls (PLAN-A)

Results of a feasibility cluster randomised controlled trial of a peer-led school-based intervention to increase the physical activity of adolescent girls (PLAN-A)

... PLAN-A intervention was carefully adapted from an ef- fective adolescent smoking cessation intervention model through formative work with key stakeholders ...the intervention used a novel means of ... See full document

13

Evaluation of an evidence-based guidance on the reduction of physical restraints in nursing homes: a cluster-randomised controlled trial [ISRCTN34974819]

Evaluation of an evidence-based guidance on the reduction of physical restraints in nursing homes: a cluster-randomised controlled trial [ISRCTN34974819]

... controlled trial with nursing homes randomised either to the intervention group or to the control group with standard ...The intervention comprises a structured information programme ... See full document

6

A randomised controlled trial of the clinical and cost effectiveness of a contingency management intervention compared to treatment as usual for reduction of cannabis use and of relapse in early psychosis (CIRCLE) : a study protocol for a randomised contr

A randomised controlled trial of the clinical and cost effectiveness of a contingency management intervention compared to treatment as usual for reduction of cannabis use and of relapse in early psychosis (CIRCLE) : a study protocol for a randomised controlled trial

... rater-blinded randomised controlled trial (RCT) investigating the clinical and cost- effectiveness of a CM intervention for reducing cannabis use among young people receiving treatment from UK ... See full document

11

A Randomised Controlled Trial of an Energy Efficiency Intervention for Families Living in Fuel Poverty

A Randomised Controlled Trial of an Energy Efficiency Intervention for Families Living in Fuel Poverty

... been randomised across the trial and control group, and will have stayed constant over the period of the ...the trial and control group or assessment of gains resulting from the fuel ... See full document

31

A randomised controlled trial of the clinical and cost effectiveness of a contingency management intervention compared to treatment as usual for reduction of cannabis use and of relapse in early psychosis (CIRCLE): a study protocol for a randomised contro

A randomised controlled trial of the clinical and cost effectiveness of a contingency management intervention compared to treatment as usual for reduction of cannabis use and of relapse in early psychosis (CIRCLE): a study protocol for a randomised controlled trial

... rater-blinded randomised controlled trial (RCT) investigating the clinical and cost- effectiveness of a CM intervention for reducing cannabis use among young people receiving treatment from UK ... See full document

10

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