[PDF] Top 20 Circulating nucleic acids as biomarkers in breast cancer

... as biomarkers in clinical practice is their sensitivity and specifi city, particularly given the poorly characterized analytical ...with breast cancer and healthy ...blood-based biomarkers in ... See full document

... in breast cancer cell-secreted exosomes and to investigate the potential of these miRNAs to function as circulating biomarkers for breast ...this breast cancer ... See full document

... potential biomarkers for colorectal cancer ...for breast cancer ...from breast cancer patients, and plasma from matched healthy ...of breast cancer ...170 ... See full document

... novel biomarkers for the breast ...and breast tumor progress and metastasis can be seen over the damage of cancer reducing miRNAs or the overexpression of oncogenic miRNAs in breast ... See full document

... ABSTRACT Circulating microRNAs have drawn a great deal of attention as promising novel biomarkers for breast ...from breast cancer patients and healthy controls, with efforts taken to ... See full document

... Breast cancer is the most common malignancy in women worldwide, and ovarian cancer is the most lethal gynecological ...developing breast and ovarian ...for breast cancer, but it ... See full document

... with cancer from healthy individuals according to cfDNA methylation ...epigenetic biomarkers with the use of new technologies, for example, next-generation DNA-methyl- ation sequencing to obtain both ... See full document

... this circulating molecule represents a promising organ-speci fi c biomarker for allograft ...Other nucleic acid molecules released from the transplanted organ (eg, microRNAs) are presently less well ... See full document

... that breast cancer patients have a different expression profile of angiogenesis-related factors when compared to pa- tients with benign breast ...specific biomarkers with prognostic ... See full document

... in breast cancer cells and function as oncomiRNAs (Garofalo et ...promotes breast cancer cell proliferation, migration, and in- vasion by targeting PTEN, a tumor suppressor gene (Li et ... See full document

... Abstract: Breast cancer is one of the most frequently diagnosed cancers among women in the western ...diagnosis, breast cancer has been constantly ...are biomarkers routinely ...in ... See full document

... rantly expressed tumor proteins in breast cancer. Six correct ORF phage-expressed proteins were isolated and the corresponding antibody activities were measured by ELISA. The classifier using three combined ... See full document

... A cancer biomarker refers to a substance or process that is used as an indicative the presence of cancer in the ...of cancer. Biomarkers are utilized in three elementary ways as a diagnostic ... See full document

... Discussion To our knowledge, this study represents the largest ana- lysis evaluating a set of five biomarkers in CTCs from sequential blood samples of patients with non-metastatic BC. In our work, we found a ... See full document

... contralateral breast measurements could be used for the z-score normalization algorithm; therefore, only n = 158 of the n = 181 subjects with malignant lesions were ... See full document

... of cancer is vital to improved overall survival ...means. Circulating tumor cells and extracellular nucleic acids have been detected within blood, plasma, and sera of cancer ... See full document

... of circulating nucleic acids in plasma and serum (CNAPS) is not a new ...in cancer patients, and that CNAPS might carry a variety of genetic and epigenetic alterations related to cancer ... See full document

... in breast and prostate cancers ...that circulating miR-10b was higher in ER (es- trogen receptor)-negative patients than in ER-positive ones, but it cannot discriminate breast cancer from ... See full document

... The studies described above are not claimed to be comprehensive, but they provide insight into the clinical relevance of cfDNA levels and integrity in different popu- lations of patients with BC. They demonstrate that ... See full document

... All of the aforementioned characterisation methods are performed on the total EV population, which is likely to comprise exosomes, microvesicles and other non-vesic- ular components. As previously mentioned, EV isolation ... See full document