[PDF] Top 20 Classical Swine Fever Virus p7 Protein Is a Viroporin Involved in Virulence in Swine
Has 10000 "Classical Swine Fever Virus p7 Protein Is a Viroporin Involved in Virulence in Swine" found on our website. Below are the top 20 most common "Classical Swine Fever Virus p7 Protein Is a Viroporin Involved in Virulence in Swine".
Classical Swine Fever Virus p7 Protein Is a Viroporin Involved in Virulence in Swine
... nonstructural protein p7 of classical swine fever virus (CSFV) is a small hydrophobic polypeptide with an apparent molecu- lar mass of 6 to 7 ...The protein contains two ... See full document
14
Mutations in Classical Swine Fever Virus NS4B Affect Virulence in Swine
... It is possible that during BICv infection of macrophages, NS4B interferes with the activation of TLR-7, either through direct TIR-to-TIR interaction with TLR-7 or possibly by competition for MyD88. This would explain the ... See full document
14
The E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in Swine
... pestivirus virulence are largely ...viral protein or genomic region in ...the virus for pigs ...be involved in CSFV virulence, since deletion of N pro in the vir- ulent Eystrup strain ... See full document
10
Determinants of Virulence of Classical Swine Fever Virus Strain Brescia
... related classical swine fever virus (CSFV) strain Brescia clones were isolated from blood samples from an infected ...the virulence of CSFV in ...envelope protein E2 seemed to be ... See full document
12
N-Linked Glycosylation Status of Classical Swine Fever Virus Strain Brescia E2 Glycoprotein Influences Virulence in Swine
... or virus infectivity in cultured swine macrophages or the natural host, with one individual site, N116, involved in attenuation of the virulent parental ...of virus virulence and host ... See full document
10
Alteration of a Second Putative Fusion Peptide of Structural Glycoprotein E2 of Classical Swine Fever Virus Alters Virus Replication and Virulence in Swine
... structural protein E2 of classical swine fever virus ...domestic swine, the natural host of CSFV host, we observed that the virus was now completely attenuated in ...the ... See full document
10
Poly(C)-Binding Protein 1, a Novel Npro-Interacting Protein Involved in Classical Swine Fever Virus Growth
... Glutathione beads conjugated to GST or the GST-N pro fusion protein were incubated with recombinant PCBP1. After washing, proteins were eluted from the beads and SDS-PAGE was performed. The presence of PCBP1 was ... See full document
9
Cytopathogenic and Noncytopathogenic RNA Replicons of Classical Swine Fever Virus
... ⌬4263, -⌬4764Ubi, and -⌬4764 are cytopathogenic replicons. NCP replicons encode NS2-NS3, replicate at low levels, and persist in transfected cells for at least 10 cell passages (data not shown). NS3 expressed by NCP ... See full document
8
Interaction of Classical Swine Fever Virus with Membrane-Associated Heparan Sulfate: Role for Virus Replication In Vivo and Virulence
... of virus isolated from pigs infected with CoBrB.E rns (S-ST) virus indicated that replication in vivo induced no mu- tations in the genes encoding the three envelope ...Thus, virus samples from these ... See full document
11
Selection of Classical Swine Fever Virus with Enhanced Pathogenicity Reveals Synergistic Virulence Determinants in E2 and NS4B
... mutant virus using a vaccine strain that had been depathogenized through adaptation in a nonnatural ...of virulence and in- creased virus replication after site-directed mutagenesis, these data show ... See full document
12
Thioredoxin 2 Is a Novel E2-Interacting Protein That Inhibits the Replication of Classical Swine Fever Virus
... cellular protein Trx2 interacts with the E2 protein of CSFV and inhibits viral ...E2 protein were shown to be critical for the ...E2 protein that is critical for Trx2 interac- tion is highly ... See full document
15
Hemoglobin Subunit Beta Interacts with the Capsid Protein and Antagonizes the Growth of Classical Swine Fever Virus
... C protein with cellular molecules impairs the host’s immune response through mechanisms that result in the suppression of interleukin-12 syn- thesis in human macrophages (37), T cell dysfunction (38), and ... See full document
11
The Laminin Receptor Is a Cellular Attachment Receptor for Classical Swine Fever Virus
... is involved in CSFV invasion, possibly as a FIG 1 Overview of pool of siRNAs against porcine membrane protein genes used in the screening to identify genes required for CSFV ... See full document
13
Cytopathogenicity of Classical Swine Fever Virus Correlates with Attenuation in the Natural Host
... pathogens classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV), cytopathogenic (cp) and non-cp viruses are distinguished according to the induction of apoptosis in ... See full document
13
Substitution of Specific Cysteine Residues in the E1 Glycoprotein of Classical Swine Fever Virus Strain Brescia Affects Formation of E1-E2 Heterodimers and Alters Virulence in Swine
... in swine and characterized by decreased viral loads in target organs and reduced virus ...of virus attachment and/or efficiency of entry into critical target cells in vivo or altered trafficking of ... See full document
9
Classical Swine Fever Virus Glycoprotein Erns Is an Endoribonuclease with an Unusual Base Specificity
... Institut fu¨r Virologie, Justus-Liebig-Universita¨t, D-35392 Giessen, Germany Received 2 October 2003/Accepted 22 January 2004 The glycoprotein E rns of pestiviruses is a virion-associated and -secreted RNase that is ... See full document
6
In vitroinfection with classical swine fever virus inhibits the transcription of immune response genes
... is involved in inhibiting host immune response gene ex- pression in vitro, both during entry into the cell as well as during ...with protein levels measured by Western blot analysis of CSFV-infected PK-15 ... See full document
11
Classical Swine Fever
... Diagnostic Tests CSFV can be detected in blood or tonsil swabs collected from live animals, or in tissue samples (tonsils, pharyngeal and mesenteric lymph nodes, spleen, kidneys, distal ileum) taken at necropsy. Samples ... See full document
6
Vulnerability of the British swine industry to classical swine fever
... Mathematical models that simulate the course of epidemics are regularly used to provide guidance for decision-making to control outbreaks of notifiable diseases. Parameterisation of these models can be challeng- ing and ... See full document
17
CiteSeerX — with a highly virulent classical swine fever virus
... higher fever frequency, and higher virus load were observed in 10 4 TCID 50 ...the virus, thus dose effects were not revealed; 3) The differences are not statistically significantly different in most ... See full document
7
Related subjects