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[PDF] Top 20 Clinical and biological implications of <em>IDH1/2</em> in acute myeloid leukemia with <em>DNMT3A<sup>mut</sup></em>

Has 10000 "Clinical and biological implications of <em>IDH1/2</em> in acute myeloid leukemia with <em>DNMT3A<sup>mut</sup></em>" found on our website. Below are the top 20 most common "Clinical and biological implications of <em>IDH1/2</em> in acute myeloid leukemia with <em>DNMT3A<sup>mut</sup></em>".

Clinical and biological implications of &lt;em&gt;IDH1/2&lt;/em&gt; in acute myeloid leukemia with &lt;em&gt;DNMT3A&lt;sup&gt;mut&lt;/sup&gt;&lt;/em&gt;

Clinical and biological implications of <em>IDH1/2</em> in acute myeloid leukemia with <em>DNMT3A<sup>mut</sup></em>

... the IDH1/2 mutation, we stratified the data by several aspects, such as age, WBC count, percentages of BM blasts and PB blasts, mutated recurrent gene numbers, and frequently mutated genes, such as FLT3 and ... See full document

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Biological and clinical influences of &lt;em&gt;NPM1 &lt;/em&gt;in acute myeloid leukemia patients with &lt;em&gt;DNMT3A&lt;/em&gt; mutations

Biological and clinical influences of <em>NPM1 </em>in acute myeloid leukemia patients with <em>DNMT3A</em> mutations

... Purpose: DNMT3A and NPM1 mutations are known to impact the prognosis of acute myeloid leukemia ...(AML). DNMT3A mutations are negative prognostic factors, while NPM1 mutations are ... See full document

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Higher expression levels of the &lt;em&gt;HOXA9&lt;/em&gt; gene, closely associated with &lt;em&gt;MLL-PTD&lt;/em&gt; and &lt;em&gt;EZH2&lt;/em&gt; mutations, predict inferior outcome in acute myeloid leukemia

Higher expression levels of the <em>HOXA9</em> gene, closely associated with <em>MLL-PTD</em> and <em>EZH2</em> mutations, predict inferior outcome in acute myeloid leukemia

... the biological insight of acute myeloid leukemia (AML) has increased in the past few years, the discovery of novel discriminative biomarkers remains of utmost value for improving outcome ... See full document

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&lt;p&gt;&lt;em&gt;BCOR&lt;/em&gt; mutation and &lt;em&gt;TLS-ERG&lt;/em&gt; expression in acute myeloid leukemia with monoclonal immunoglobulinemia&lt;/p&gt;

<p><em>BCOR</em> mutation and <em>TLS-ERG</em> expression in acute myeloid leukemia with monoclonal immunoglobulinemia</p>

... TLS-ERG leukemia fusion protein inhibits E1A premRNA ...myelomonocytic leukemia (CMML), MDS, aplastic anemia, and often coincide with DNMT3 gene mutations, suggesting that it may affect the occurrence of ... See full document

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&lt;em&gt;RASSF1A&lt;/em&gt; hypermethylation is associated with &lt;em&gt;ASXL1&lt;/em&gt; mutation and indicates an adverse outcome in non-M3 acute myeloid leukemia

<em>RASSF1A</em> hypermethylation is associated with <em>ASXL1</em> mutation and indicates an adverse outcome in non-M3 acute myeloid leukemia

... CEBPA, DNMT3A, FLT3, IDH1, KIT, NPM1, NRAS, RUNX1, SF3B1, SRSF2, U2AF1, and TET2 mutations were assessed in all 226 patients with non-M3 ...Figure 2. As shown in Table 2, cases with aberrant ... See full document

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&lt;p&gt;Facial skin revitalization with CPM&lt;em&gt;&lt;sup&gt;&amp;reg;&lt;/sup&gt;&lt;/em&gt;-HA20G: an effective and safe early intervention treatment&lt;/p&gt;

<p>Facial skin revitalization with CPM<em><sup>&reg;</sup></em>-HA20G: an effective and safe early intervention treatment</p>

... Summarizing the shown biophysical parameters, physician and subject ’ s satisfaction data obtained from the clinical study it can be concluded that CPM ® - HA20G treatment improves the subjects overall skin ... See full document

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Diagnostic value of &lt;em&gt;BRAF&lt;sup&gt;V600E&lt;/sup&gt;&lt;/em&gt;-mutation analysis in fine-needle aspiration of thyroid nodules: a&amp;nbsp;meta-analysis

Diagnostic value of <em>BRAF<sup>V600E</sup></em>-mutation analysis in fine-needle aspiration of thyroid nodules: a&nbsp;meta-analysis

... Systematic searches were performed in the PubMed, Web of Science, Scopus, Ovid, Elsevier, and Cochrane Library databases for relevant articles prior to June 2015. The search terms were: ([thyroid cancer] or [thyroid ... See full document

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Effects of salvianolate on bone metabolism in glucocorticoid-treated lupus-prone B6.MRL-Fas&lt;em&gt;&lt;sup&gt;lpr&lt;/sup&gt;&lt;/em&gt;/J mice

Effects of salvianolate on bone metabolism in glucocorticoid-treated lupus-prone B6.MRL-Fas<em><sup>lpr</sup></em>/J mice

... The left proximal tibia was processed for micro-CT analy- sis. The metaphyseal trabecular bone was scanned using viva CT40 (Scanco Medical, Zurich, Switzerland) in high- resolution condition (X-ray energy on 70 KVp, 114 ... See full document

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Quantitative assessment of aberrant &lt;em&gt;P16&lt;sup&gt;INK4a&lt;/sup&gt;&lt;/em&gt; methylation in ovarian cancer: a meta-analysis based on literature and TCGA datasets

Quantitative assessment of aberrant <em>P16<sup>INK4a</sup></em> methylation in ovarian cancer: a meta-analysis based on literature and TCGA datasets

... cancer; 2) articles providing suf- ficient information for calculating an odds ratio (OR) and corresponding 95% CI, or study offering hazard ratio (HR) and 95% CI directly; 3) sample types limited to tissues; and ... See full document

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The safety of a novel early mobilization protocol conducted by ICU physicians: a prospective observational study

The safety of a novel early mobilization protocol conducted by ICU physicians: a prospective observational study

... Maebashi EM protocol consists of three steps and includes five levels of ...are sup- posed to receive one rehabilitation session each day for 20 min, the actual rehabilitation period was determined by ICU ... See full document

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The contribution of &lt;em&gt;XRCC3 &lt;/em&gt;genotypes to childhood acute lymphoblastic leukemia

The contribution of <em>XRCC3 </em>genotypes to childhood acute lymphoblastic leukemia

... The authors are grateful to Hsin-Ting Li, Yu-Shih Wang, and Huai-Mei Hsu for their excellent technical assistance. All the participants in this study are appreciated. This study was supported mainly by Taoyuan General ... See full document

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Higher &lt;em&gt;FKBP5&lt;/em&gt;, &lt;em&gt;COMT&lt;/em&gt;, &lt;em&gt;CHRNA5&lt;/em&gt;, and &lt;em&gt;CRHR1&lt;/em&gt; allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment

Higher <em>FKBP5</em>, <em>COMT</em>, <em>CHRNA5</em>, and <em>CRHR1</em> allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment

... Conclusion: A cumulative risk allele count involving four single nucleotide polymorphisms located within the FKBP5, COMT, CHRNA5, and CRHR1 genes are associated with PTSD. Level of trauma exposure interacts with risk ... See full document

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Identification of key pathways and genes in &lt;em&gt;TP53 &lt;/em&gt;mutation acute myeloid leukemia: evidence from bioinformatics analysis

Identification of key pathways and genes in <em>TP53 </em>mutation acute myeloid leukemia: evidence from bioinformatics analysis

... In this study, we observed that TP53 mRNA expression was similar between TP53 mutation and wild-type patients’ bone marrow tissue (Figure 6A). Overall, 151 patients with a 7.3% lost follow-up rate were included in the ... See full document

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Relationship between the &lt;em&gt;iceA&lt;/em&gt; gene of &lt;em&gt;Helicobacter pylori&lt;/em&gt; and clinical outcomes

Relationship between the <em>iceA</em> gene of <em>Helicobacter pylori</em> and clinical outcomes

... Background: The complex pathogenesis of Helicobacter pylori (H. pylori) and the features of the host influence the diverse clinical outcomes. A mass of studies about virulence genes have accelerated the ... See full document

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Comparison of &lt;em&gt;CYP2C9&lt;/em&gt;, &lt;em&gt;CYP2C19&lt;/em&gt;, &lt;em&gt;CYP2D6&lt;/em&gt;, &lt;em&gt;ABCB1&lt;/em&gt;, and &lt;em&gt;SLCO1B1&lt;/em&gt; gene-polymorphism frequency in Russian and Nanai populations

Comparison of <em>CYP2C9</em>, <em>CYP2C19</em>, <em>CYP2D6</em>, <em>ABCB1</em>, and <em>SLCO1B1</em> gene-polymorphism frequency in Russian and Nanai populations

... berg equilibrium, so we did not compare the frequency of its mutant alleles in Russian or Nanai groups. The Nanai group consisted of healthy volunteers, living on the terri- tory historically occupied by this ethnic ... See full document

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&lt;em&gt;EGFR&lt;/em&gt;, &lt;em&gt;KRAS&lt;/em&gt;, &lt;em&gt;BRAF&lt;/em&gt;, &lt;em&gt;PTEN&lt;/em&gt;, and &lt;em&gt;PIK3CA &lt;/em&gt;mutation in plasma of small cell lung cancer patients

<em>EGFR</em>, <em>KRAS</em>, <em>BRAF</em>, <em>PTEN</em>, and <em>PIK3CA </em>mutation in plasma of small cell lung cancer patients

... in 2 (2.02%) patients, KRAS 2 (G13D) mutation in 5 ...(Figure 2), and no mutations of PTEN 5 (R130G), PTEN 6 (R173C), PTEN 8 (T319fs*1), and PIK3CA 20 (H1047R) were ... See full document

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&lt;em&gt;Shen-Qi-Jie-Yu-Fang&lt;/em&gt; exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4&lt;sup&gt;+&lt;/sup&gt;CD25&lt;sup&gt;+&lt;/sup&gt; regulatory T cells

<em>Shen-Qi-Jie-Yu-Fang</em> exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4<sup>+</sup>CD25<sup>+</sup> regulatory T cells

... Materials and methods: Sprague Dawley rats were used to create an animal model of PPD by inducing hormone-simulated pregnancy followed by hormone withdrawal. After hormone withdrawal, the PPD rats were treated with SJF ... See full document

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Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD&amp;ndash;&lt;em&gt;scid&lt;/em&gt; &lt;em&gt;IL-2rg&lt;sup&gt;null&lt;/sup&gt;&lt;/em&gt; RIP-DTR mice engrafted with human islets

Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD&ndash;<em>scid</em> <em>IL-2rg<sup>null</sup></em> RIP-DTR mice engrafted with human islets

... At 2 weeks post-transplant, the fasting levels of human insu- lin showed no significant differences between control and any of the lixisenatide-treatment groups (Figure ...Donor 2 and 5 transplant studies ... See full document

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&lt;em&gt;DUSP4&lt;/em&gt;/MKP2 overexpression is associated with BRAF&lt;sup&gt;V600E&lt;/sup&gt; mutation and aggressive behavior of&amp;nbsp;papillary thyroid cancer

<em>DUSP4</em>/MKP2 overexpression is associated with BRAF<sup>V600E</sup> mutation and aggressive behavior of&nbsp;papillary thyroid cancer

... patients’ clinical fea- tures including sex, age at diagnosis, maximum size of tumor, multifocality, Hashimoto’s thyroiditis, histological types, ETE, and cervical LNM were retrospectively abstracted from patient ... See full document

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&lt;p&gt;Curcumin Combined with Thalidomide Reduces Expression of &lt;em&gt;STAT3&lt;/em&gt; and &lt;em&gt;Bcl-xL&lt;/em&gt;, Leading to Apoptosis in Acute Myeloid Leukemia Cell Lines&lt;/p&gt;

<p>Curcumin Combined with Thalidomide Reduces Expression of <em>STAT3</em> and <em>Bcl-xL</em>, Leading to Apoptosis in Acute Myeloid Leukemia Cell Lines</p>

... Introduction: Acute myeloid leukemia (AML) is a type of blood disorder that exhibits uncontrolled growth and reduced ability to undergo apoptosis. Signal transducer and acti- vator of transcription 3 ... See full document

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