[PDF] Top 20 Clinical drug trials in general practice: a 10 year overview of protocols

... Esomeprazole was launched in 2001 in a crowded drug group. It is the most expensive of the proton pump in- hibitors, and had become the tenth most-sold medicine in Norway in 2008 calculated in terms of pharmacy ... See full document

... in general practice and general practice research is growing [39], fuelled by the need to provide health care to an ageing and increasingly multi-morbid population while containing ...last ... See full document

... contributors ELT, SEO, YB-S, JAL, DEN, FCH, JLD, RMM and CM contributed to the design of the study and formulated the research question. SH, ELT, EIW, RMM and CM contributed to the acquisition of the data. GJY, SH, ELT, ... See full document

... the practice as an antiarrhythmic for patients with atrial fibrillation ...of drug-induced TdP and despite some reservations QT prolongation is currently recognized as an underlying cause of development of ... See full document

... CMR: Clinical medication review; CONSORT: Consolidated standards of reporting trials; DRP: Drug related problems; GP: General practitioner; ICER: Incremental cost-effectiveness ratio; ICPC: ... See full document

... of general hospitals, there are actually two types of ECs [23]: an EC that reviews and monitors drug clinical trials called a chiken-shinsa- iinkai (clinical trial review committee), ... See full document

... Adverse Drug Reaction Monitoring Programme based in Uppsala, Sweden in ...of Clinical Pharmacology, Seth GS Medical College and KEM located in the Department of Pharmacology, AIIMS, New Delhi), were also ... See full document

... SNMP is the low communication overhead protocol that assures confidentiality, data freshness and data authentication. This protocol ensures authentication and protection against replay attack through encryption technique ... See full document

... transdermal drug active or passive designed affected person thru a permeable reservoir of medication or via the layers of the medication deposited most important disadvantage to shape the fact that the pores and ... See full document

... all, clinical investigators may not charge money for patients taking part in clinical studies, and hospitals are not allowed to advertise stem cell trials as ... See full document

... internationally practice-changing trials [66], there is an obligation to answer the question as to whether the dosimetric benefits of PBT translate into meaningful clinical benefits ...opportunity, ... See full document

... show clinical effi- cacy in a Phase III clinical trial in 2007 ...anti-inflammatory drug (NSAID) that inhibits cyclooxy- genase activity and further reduces inflammation through reduced prostaglandin ... See full document

... master protocols is provided in Additional file 1: Table ...master protocols observed from low-income countries, although the EBOLA (NCT02380625) trial had been proposed for Guinea, Sierra Leone, and ... See full document

... ized, multicenter, double-blind, parallel-group, dose-ranging prospective clinical trial performed in young individuals of any race, aged 6 to 16 years, and presenting with primary or secondary hypertension. The ... See full document

... controlled clinical trial to compare the clinical effectiveness of bonded retainers with vacuum-formed retainers, in terms of maintaining the results of orthodontic treatment in the lower arch up to 18  ... See full document

... tional trials, trials of drug interventions alone were likely to be published later than those of drug and psycho- logical interventions, psychological interventions alone and those assessing ... See full document

... Conventional RBL uses a simple suction device that is applied to each haemorrhoid via a disposable proctoscope. A rubber band is then fired onto the base of the haemor- rhoid which constricts the blood supply causing it ... See full document

... Restoration Act of 1984," also known as the Waxman-Hatch Act. This Act expedites the availability of less costly generic drugs by permitting FDA to approve applications to market generic versions of brand-name drugs ... See full document

... first year to 3,600 in ...the Clinical Research Network – shifting the focus from treatment to the evaluation and monitor- ing of ...the Clinical Research Network was reformulated into the Access to ... See full document

... available drug may be categorised either as a responder or as a non responder to a given ...made drug, while other patients would receive the ‘bulk drug’ that is known not to be the ideal medicine ... See full document