[PDF] Top 20 Clinical potential of lixisenatide once daily treatment for type 2 diabetes mellitus

... American Diabetes Association 2012 meeting, tested the effect of a morning administration of lixisenatide on postprandial glycemia throughout the ...(Figure 2). Thus, it seems that ... See full document

... 3 clinical trials that treatment with liraglutide is associated with significant improvement in fasting and postprandial glucose and HbA 1c ...twice daily injections of exenatide, liraglutide with ... See full document

... insulin per kilogram dosing. In the present study, the unit dose of insulin increased with increasing BMI, how- ever, the unit per kilogram dose was similar across all four BMI subgroups (0.26-0.29 units/kg at the final ... See full document

... 2012, and also information for 2007 to 2012 from the Glasgow DAFNE service, which does not participate in the research database. All patients undertook DAFNE training as part of their routine clinical care. Course ... See full document

... the 2 months after stopping diclofenac treatment from around 10% to 20% compared with pre-treatment ...diclofenac treatment is, therefore, difficult to ... See full document

... in diabetes treatment because of their frequent gastrointestinal side effects (Campbell 2009b; Olokoba et ...of type 2 diabetes mellitus as it was shown in rodent models that ... See full document

... exenatide once-weekly ...on diabetes duration, diabetes-related complications, glycated hemoglobin levels, and other clinical characteristics were not available in the ... See full document

... treatment satisfaction and weight-related quality of life in patients with type 2 diabetes mellitus treated with either exenatide BID or exenatide QW were assessed over 1 ...overall ... See full document

... present, clinical experience with these agents is still relatively limited, with exenatide being the only incretin mimetic so far to be approved for treatment of T2DM (launched in ...In clinical ... See full document

... given once daily using the IMS Core Diabetes Model to project clinical and economic outcomes for patients with T2DM in the UK treated with exenatide ER or insulin ... See full document

... multiple-ascending-dose clinical trial, healthy individuals received diets containing fixed amounts of calcium and sodium chloride and were assigned to receive dapagliflozin ...= 2 per dose level). Similar ... See full document

... mg daily or placebo. At study end, sitagliptin treatment produced a significant reduction in A1c ...mg once daily was well tolerated and provided sustained improvements in A1c and FPG in ... See full document

... that treatment with sulbutiamine at the dosage of 400mg daily over 6 weeks in type 2 diabetes mellitus patients was associated with significant improvement in nerve conduction ... See full document

... T2DM. Once-daily dosing is the most commonly used detemir regimen reported in observational studies, and controlled clinical studies indicate that once-daily dosing controls ... See full document

... two treatment arms while continuing with maximally optimized glargine therapy for a further 6 months, with both lixisenatide and insulin glargine injected in the morning within 1 hour prior to ...with ... See full document

... voluntarily, 2 patients who started on insulin, and 1 patient who unilaterally decided to resume treat- ment with standard metformin without seeking medical ...anthropometric, clinical or laboratory ... See full document

... the treatment of type 2 diabetes ...its clinical application. The exenatide products on the market, twice-daily Byetta™ and once-weekly Bydureon™ (both Amylin ... See full document

... For up to 24 weeks, 2523 patients received linagliptin 5 mg once daily, and 1049 have received placebo. The overall incidence of adverse events (AE) or serious AE with linagliptin was similar to those of ... See full document

... with type 1 diabetes mellitus or gestational diabetes, studies that did not report information regarding the associations of the intervention with HbA1c levels in the experimental group or ... See full document

... H. pylori negative, H. pylori positive, and H. pylori suc- cessfully eradicated cases were 114 (44.7%), 94 (36.9%), and 47 (18.4%), respectively. The mean time interval since successful eradication of H. pylori was 4.4 ± ... See full document