[PDF] Top 20 A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma

... Recently, p73, a novel structural and functional homologue of p53 was identified (Kaghad et al, ...1997). p73 maps to chromosome 1p36 (Kaghad et al, 1997), a region deleted in up to 40% of ... See full document

... Quality Assessment The studies included in the meta-analysis were ranked as be- ing medium (11) to high quality (11) with the exception of two studies [ 20 , 30 ]. A more detailed breakdown of study quality assessment ... See full document

... most common strain (CagA þ ) of Helicobacter pylori has been established as a risk factor for non-cardia gastric cancer (International Agency for Research on Cancer, 1994), meta-analyses have found that such ... See full document

... To investigate the function connection of ADH1B in the regulation of ESCC cell proliferation, we further evaluate the proliferation capacity of cells transfected with ADH1B ( GG or AA ) plasmid. Notably, cells ... See full document

... MNS16A polymorphism was associated with clinical progression in some types of cancer, including clinical stage, tumor stage, lymph-node metastasis and survival time, although the results were ... See full document

... Leptin is an endocrine hormone that inhibits food intake and increases energy expenditure by acting on the hypothalamus [46] . In the present study, the SNP rs7566605 genotypes were significantly associated with ... See full document

... COMT polymorphism, may have led to differences in the chosen operative and narcotic strategy, intra opera- tive and early postoperative ...was associated with a higher risk for post- operative ... See full document

... Stronger evidence that TLR1 rs5743551 may influ- ence host responses to malaria is provided by the finding of a significant association between the copy number of the T allele of this polymorphism and increased ... See full document

... Two common non- synonymous coding region polymorphisms (677C>T and 1298A>C) in the MTHFR gene were shown to reduced enzyme activity in vitro assays leading to a decreased of methyl- THF [5] ... See full document

... the p73 rs6695978 G > A A allele as the at-risk allele may en- hance susceptibility to ovarian cancer in Chinese ...positively associated with the occur- rence of mucinous ovarian cancer, poor ... See full document

... An additional relevant finding of our study is that sarcopenia was prevalent in 49% of overweight/obese patients (BMI  25). This observation confirms the warning that sarcopenia is not exclusively to be sought in patients ... See full document

... increasingly associated with the development of hepatocellular carcinoma ...the incidence of HCC in patients with NASH- related cirrhosis, (2) compare incidence in NASH-related cirrhosis with ... See full document

... promote p73 degradation through interaction with ITCH in HeLa cells ...regulates p73 stability, wild type MEFs and Mdm2 null MEFs were treated with cycloheximide to inhibit de novo protein ...endogenous ... See full document

... Metastatic spread of breast cancer is invariably associated with death from the disease. The median survival from the manifestation of metastases is about 3 years in most reported series. Metastatic disease can be ... See full document

... Results—Twenty seven primary articles were assessed in detail. Thirteen supplied results for staging oesophageal cancer, 13 for gastric cancer, and four for cancers at the gastro-oesophageal junction. For ... See full document

... length polymorphism analysis and DNA sequencing based on the sequence variations of EBV ...more common worldwide, whereas Type 2 is equally prevalent in parts of Africa ... See full document

... As males and females differ with respect to several of the biochemical and lifestyle variables (Table 1) of interest in this study, further analyses were performed separately for males and females. Median values of the ... See full document

... Daily medication is a constant reminder even to patients with well-controlled epilepsy that they harbor an unpre- dictable disorder that may recur at any time. Until patients are seizure-free without medication, they may ... See full document

... In conclusion, our findings revealed no association between the apoptotic pathway proteins of study and the clinicopatho- logical characteristics of patients with cervical carcinoma, while a reverse correlation ... See full document

... In this retrospective analysis of 17,145 patients receiving in- center HD, Tego connector use was found to be independently associated with a 10%–12% reduction in risk of CRBSIs, as defined by initiation of IV ... See full document