[PDF] Top 20 Comparison of Mycobacterium tuberculosis drug susceptibility using solid and liquid culture in Nigeria

... Liquid culture has been reported to detect more cases of first-line drug resistance than LJ by some [16] but not all studies, while others report a higher recovery rate of MTbC but similar ... See full document

... Observation Drug Susceptibility (MODS) technique is an easy and transferable method for MTB isolation and is well suited to laboratories in developing ...tissue culture plates. 5 The “cording” growth ... See full document

... the liquid conditions, possibly due to differences in metabolic profile of the bacteria FIG 3 Comparison between the delay (Δ) in the time to positivity (TTP) results using the TB-eXiST protocol on ... See full document

... being culture based, required time to obtain an adequate ...obtained using a seed tube from the primary MGIT culture, the turnaround time was good; however this method required the most repeat ... See full document

... and drug susceptibility of Mycobacterium tuberculosis (MTB) are crucial to the control of ...broth-drug susceptibility assay (MODS) detects early growth of MTB in liquid ... See full document

... This observa- tion deserves further study, because it implies that the critical concentration of EB used in the standard PR method (Loewenstein-Jensen medi- um), cannot be equated to the[r] ... See full document

... TB culture and DST is very ...M. tuberculosis in this part of the ...the drug resistance patterns of Mycobacterium tuber- culosis against the first line drugs in patients diagnosed with ... See full document

... D); specificity, A/(A + B); predictive value (resist- ance), D/(B + D); predictive value (susceptibility), A/ (A + C), where A is when the test strain was found susceptible by both metho[r] ... See full document

... Putting all accounts together, the application of such rapid molecular methods to the detection of drug resistance will have an important impact on the future control of drug-resistant tuberculosis, ... See full document

... in comparison with the BACTEC 460TB system was evaluated in terms of sensitivity, specificity, and positive and negative likelihood ratios for the two drugs ... See full document

... ince using MIRU-VNTR-24 locus analysis and to under- stand the genetic diversity of Beijing and non-Beijing isolates by the RD105 deletion ...determine drug susceptibility patterns of the MTB ... See full document

... traditional culture based procedures to rapidly screen for drug ...of drug resistant strains as reported previously (van Rie et ...in drug surveillance studies to further improve the ... See full document

... Managing drug-resistant Mycobacterium tuberculosis requires drug susceptibility testing, yet conventional drug susceptibility testing is slow, and molecular testing does ... See full document

... Multidrug-resistant tuberculosis is an increasing public health concern in many parts of the world, especially in low- income countries, where most cases ...Traditional drug susceptibility testing is ... See full document

... strains. Drug susceptibility patterns Susceptibility testing showed that six isolates were resis- tant to rifampicin, and four to isoniazid, with two isonia- zid resistant isolates being rifampicin ... See full document

... Another nontechnical but important point is the price. It seems that the time taken to perform the test and the cost incurred are, in general, inversely proportional. For this work we have used a commercially available ... See full document

... A total of 224 recent isolates of Mycobacterium tuberculosis from 163 patients selected to have multidrug resistance were tested against streptomycin (SM), isoiiazid, rifampin, and etham[r] ... See full document

... which susceptibility results are well ...M. tuberculosis H37Rv (ATCC 27294) strain is currently recommended by the CLSI ...high drug concentrations, the ideal reference strain would be the one that ... See full document

... tuberculosis is a wide-scale application of rapid diagnostic tests capable of identifying drug resistance in order to initiate appro- priate treatment earlier and halt further transmission. MODS is a rapid ... See full document

... of drug-resistant Mycobacterium tuberculosis strains are on the rise, the simple classification into “susceptible” and “resistant” strains based on susceptibility testing at “critical ... See full document