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18 results with keyword: 'control of the embryonic stem cell state'

Control of the Embryonic Stem Cell State

Thus the functions of the core regulators (Oct4, Sox2, and Nanog) are augmented by the functions of many the other transcription factors implicated in control of ESC state at

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2021
Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening

ARVD/C: Arrhythmogenic right ventricular dysplasia/cardiomyopathy; ESC: Embryonic stem cell; ESC-CM: Embryonic stem cell-derived cardiomyocyte; hESC: Human embryonic stem cell;

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8
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2020
Phenotypic and Metabolic Plasticity In Canine Cellular Reprogramming

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Canine, Pluripotency, Naïve Pluripotent State, Metabolism, Mitochondria, DNA Methylation, TET Dioxygenase...

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245
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2021
microRNAs: important regulators of stem cells

EC: Endothelial cell; ESC: Embryonic stem cell; ESCC: Embryonic stem cell-specific; FAK: Focal adhesion kinase; HSC: Hematopoietic stem cell; iPSC: Induced pluripotent stem cell;

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7
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2020
Systems biology discoveries using non-human primate pluripotent stem and germ cells: novel gene and genomic imprinting interactions as well as unique expression patterns

BMP = bone morphogenetic protein; EB = embryoid body; EGC = embryonic germ cell; ESC = embryonic stem cell; hESC = human embryonic stem cell; invPGC = in vitro - derived

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2020
Computational modelling of embryonic stem cell fate control

recently analysed single-cell expression dynamics, demonstrating that Nanog heterogeneity arises from a combination of stochastic transitions between coexisting gene expression

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2020
Understanding development and stem cells using single cell based analyses of gene expression

CEL-Seq, cell expression by linear amplification and sequencing; CTCs, circulating tumor cells; ESC, embryonic stem cell; hESC, human embryonic stem cell; MEF, mouse

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2020
Stem cell technology for bone regeneration: current status and potential applications

Human embryonic stem cells undergo osteogenic differentiation in human bone marrow stromal cell microenvironments. Response of human embryonic stem cell-derived

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10
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2020
Expected advances in human fertility treatments and their likely translational consequences

BMP: bone morphogenic protein; CDC: Center for Disease Control; ESC: embryonic stem cell; FDA: Food and Drug Administration; GSC: germline stem cell; iPSC: induced pluripotent

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2020
Stem Cell Therapy: An Overview

The exogenous cell replacement strategy involves the transplantation of relevant stem cells (i.e. embryonic stem cell, induced pluripotent stem cell and adult stem cells) or fetal

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2020
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How To Cure Ovarian Cysts : Natural Treatments for Polycystic Ovary Syndrome (PCOS).. Learn How To Cure Ovarian Cysts Naturally in

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2021
Reinterpretation of evidence advanced for neo- oogenesis in mammals, in terms of a finite oocyte reserve

cyclophosphamide; EGFP: enhanced green fluorescent protein; EG: embryonic germ (cell); ES: embryonic stem (cell); FGSC: female germline stem cells; HSC: haematopoietic stem cells;

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2020
Jewish and Islamic Ethical Perspectives on Human Stem Cell Research

The presentation began with a short background on human stem cell research, including the four types of stem cells: human embryonic stem cells (hESC), cloned embryonic stem

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2021
Bone marrow-derived mesenchymal stromal cell: what next?

Areas of interest in stem cell research include: Embryonic cell stems; Adult stem cells; Blastocysts; Cordblood stem cells; Stem cell transformation and culture; Therapeutic

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7
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2020
Tracking the embryonic stem cell transition from ground state pluripotency

For subsequent analyses, we selected and defined cell populations as follows: 2i- cells represent the ground state; 16 h and 25h-H cells are in a reversible phase preceding

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2021
Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance

In this review, we highlight the significance of metabolism in regulating stem cell homeostasis, cell state, and differentiation capacity, using metabolic regulation of embryonic

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2021
The Epigenomics of Embryonic Stem Cell Differentiation

Gene priming and gene bivalency though, are not restricted to ESCs and are found in other cell types including hematopoietic stem cells as well as T-cells where bivalent

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2020
The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells

The miR‑290‑295 cluster is involved in regulating embry‑ onic stem cell pluripotency maintenance, self‑renewal, and reprogramming somatic cells to an embryonic stem cell‑

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10
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2020

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