[PDF] Top 20 Cross-species validation of cell cycle arrest markers for acute kidney injury in the rat during sepsis
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Cross-species validation of cell cycle arrest markers for acute kidney injury in the rat during sepsis
... the kidney to release TIMP-2 and IGFBP7 as part of an “ alarm ” that protects cells from subsequent injury ...temporary cell cycle arrest is a protective mechanism, it is reasonable to ... See full document
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Cell-cycle arrest biomarkers in urine to predict acute kidney injury in septic and non-septic critically ill patients
... studies analysing the role of classical or emerging bio- markers in ICU subjects have been done in unselected populations. Accordingly, the number of patients pre- senting different degrees of renal dysfunction is ... See full document
10
Erythrocyte superoxide dismutase as a biomarker of septic acute kidney injury
... functional markers, such as serum creatinine; up-regulated proteins, such as NGAL and IL-18; low molecular weight proteins, such as urine cys- tatin C; and enzymes, such as alpha-glutathione s-trans- ferase and ... See full document
8
Update on sepsis-associated acute kidney injury: emerging targeted therapies
... Abstract: Sepsis-associated acute kidney injury (SA-AKI) is an independent predictor of increased mortality and ...of sepsis should prioritize targeted therapies in SA-AKI in order to ... See full document
8
Acute Kidney Injury in Patients with Sepsis and Septic Shock: Risk Factors and Clinical Outcomes
... The patients who developed AKI showed more severe phys- iologic and laboratory disturbances (Table 2). The frequen- cy of septic shock was significantly higher in the patients with AKI than were those without AKI ... See full document
8
Acute kidney injury and inflammatory response of sepsis following cecal ligation and puncture in D-galactose-induced aging rats
... the acute kidney injury and inflamma- tory response of sepsis following cecal ligation and puncture in d -gal-induced aging ...of sepsis in elderly ... See full document
10
Iatrogenic salt water drowning and the hazards of a high central venous pressure
... of acute lung injury/ARDS ...endothelial injury, capillary leak and increased hydrostatic pressures less than five percent of infused crystalloid remains intravascular within three hours after ... See full document
9
Klotho ameliorates sepsis-induced acute kidney injury but is irrelevant to autophagy
... Paraffin-embedded kidney specimens were sectioned (3 μ m thickness) and incubated with 3% H 2 O 2 for 10 min. After tissue sections were washed with PBS, they were boiled in 10 mM citrate buffer (pH 6.0) for 4 min ... See full document
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Assessment of biochemical markers in the early post burn period for predicting acute kidney injury and mortality in patients with major burn injury: comparison of serum creatinine, serum cystatin C, plasma and urine neutrophil gelatinase associated lipocalin
... levels during the 48 h after admission in the groups classified according to the time of AKI devel- opment and mortality (Figures 1 and ...inhalation injury, which are known prognostic factors for burn ... See full document
12
Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes
... term acute renal failure to a set of uni- form criteria combining small changes in creatinine and urine output ultimately defining AKI ...Risk, Injury, Failure, Loss of kidney function and End-stage ... See full document
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Optimal timing of renal replacement therapy initiation in acute kidney injury: the elephant felt by the blindmen?
... appropriately, and perhaps prevent subsequent complica- tions attributable to AKI [4]. RRT initiated before the onset of severe AKI could potentially prevent the kidney-specific damage and remote organ ... See full document
7
A study of incidence and outcome of acute kidney injury in common undifferentiated febrile illnesses
... Acute undifferentiated Febrile Illness (AFI) is defined as a type of illness characterized by an acute onset of fever above 38oC without a defined cause lasting less than 14 days. Some of the most commonly ... See full document
6
Continuous venovenous hemofiltration in severely burned patients with acute kidney injury: a cohort study
... (VA/NIH) Acute Renal Failure Trial Network recently demonstrated no difference in 60-day mortality between intensive and less-intensive renal replacement ther- apy strategies in ICU patients with AKI in a large ... See full document
8
Troponin I at admission in the intensive care unit predicts the need of dialysis in septic patients
... of sepsis symptoms. Those patients with acute coronary syndrome, known previous coronary artery disease or a left ventricular ejection fraction lower than 40% by echocardiography in the first 24 h in the ... See full document
7
Hemodynamic variables and progression of acute kidney injury in critically ill patients with severe sepsis: data from the prospective observational FINNAKI study
... died during the first five days may have caused selection bias by elimination of the most severely ill patients (Additional file ...the kidney, as Table 3 Univariable and multivariable regression analyses ... See full document
11
Alkaline phosphatase for treatment of sepsis induced acute kidney injury: a prospective randomized double blind placebo controlled trial
... with sepsis, which may eventually result in less organ ...found during experimental human endotoxemia using AP [32] or during the previous trial in patients with sep- sis ...matory markers ... See full document
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Urine biomarkers give early prediction of acute kidney injury and outcome after out of hospital cardiac arrest
... The present study has several important limitations. No “gold-standard” definition of AKI exists, and the oc- currence of AKI in our study was not strictly according to the KDIGO criteria since we only assessed the first ... See full document
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Acute kidney injury 2016: diagnosis and diagnostic workup
... Risk, Injury, Failure, Loss, End-stage (RIFLE) criteria in 2004 to the AKI Network (AKIN) classification in 2007 [4, ...the Kidney Disease Improving Global Outcomes (KDIGO) classification ... See full document
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The prognostic importance of duration of AKI: a systematic review and meta-analysis
... Duration of AKI could be similar to or atleast an over- lap to the concept of “kidney recovery” at hospital dis- charge. Recently, Kellum et al. [25] characterized various patterns of kidney recovery after ... See full document
10
High urinary excretion of kidney injury molecule 1 predicts adverse outcomes in acute kidney injury: a case control study
... Acute kidney injury (AKI) is one of a number of conditions that affect kidney structure and ...The kidney normally exhibits an extremely strong capacity for self-regeneration and re- ... See full document
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