[PDF] Top 20 Curcumin Is an In Vivo Inhibitor of Angiogenesis
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Curcumin Is an In Vivo Inhibitor of Angiogenesis
... ability to inhibit the proliferation of primary endothelial cells in the presence and absence of basic fibroblast growth factor (bFGF), as well as its ability to inhibit proliferation of[r] ... See full document
8
Curcumin: the spicy modulator of breast carcinogenesis
... tumor, angiogenesis plays a key ...anti- angiogenesis treatment strategy. Curcumin has effectively demonstrated its efficiency to act as a potent antian- giogenic, anti-invasive and anti-metastatic ... See full document
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EXPERIMENTAL MODELS TO STUDY TUMOUR ANGIOGENESIS – IN VITRO, EX VIVO AND IN VIVO APPROACH
... ABSTRACT: Angiogenesis is the formation of new blood vessels from preexisting ...of angiogenesis plays a key role in the pathogenesis of some diseases through the over-proliferation of blood vessels such as ... See full document
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STUDY OF IN VIVO PHARMACOKINETIC DRUG INTERACTIONS OF CURCUMIN ON TACRINE
... esterase inhibitor (AChEI) approved to use in the treatment of Alzheimer’s Disease (AD) by the Food and Drug Administration in 1993, which was most potent and clinically effective ... See full document
7
The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development
... ongoing angiogenesis shows blood vessels contain- ing high levels of apoptotic endothelial ...during angiogenesis in the chick CAM induce endothelial cell p53-dependent DNA-binding activity, which in turn ... See full document
5
Thrombospondin 1, an inhibitor of angiogenesis, is regulated by progesterone in the human endometrium
... Thrombospondin-1 (TSP1), a multifunctional extracellular matrix glycoprotein, has been shown to suppress the angio- genic response in vivo and in vitro. We hypothesized that TSP1 might play a role in the ... See full document
11
Evaluation of in angio suppressive activity of the biophytum sensitivum (bark) extracts by chorioallantoic membrane (cam) assay
... of angiogenesis has become a promising strategy for cancer treatment by switching off the supply of oxygen and nutrients (Cook and Figg, ...in vivo method (Deryugina and Quigley, 2008) and inhibition of ... See full document
9
TAFIa is a Novel Inhibitor of Tumour Angiogenesis in Breast Cancer
... of angiogenesis is the formation of tube-like structures ...healing angiogenesis [130], however, the role of TAFI endothelial tube formation in regards to tumour angiogenesis has yet to be ...on ... See full document
159
Hepatitis C Virus NS2 Protein Is Phosphorylated by the Protein Kinase CK2 and Targeted for Degradation to the Proteasome
... proteasome inhibitor and ...in vivo (22), we could not exclude that other viral proteins might have an effect on the individual NS2 protein ...proteasome inhibitor MG132 (upper panel, lanes 1 and ... See full document
9
Antioxidative and antidiabetic effects of naringin and curcumin in vitro and in vivo
... Tween-40 (polyoxyethylene sorbitan monopalmitate), butylated hydroxyanisol (BHA), 2,2-diphenyl-1-picrylhydrazyl (DPPH), ascorbic acid, and ethylenediaminetetraacetic acid (EDTA) were purchased from Sigma-Aldrich Chemical ... See full document
9
Role of curcumin in regulating p53 in breast cancer: an overview of the mechanism of action
... by curcumin after Western blot analysis of BCSC markers (CD44, ALDH1A1, Nanog, and Oct4) that were substan- tially downregulated by curcumin also in MCF-7 ...hand, curcumin induced apoptosis of BCSCs ... See full document
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<p>In vitro and in vivo Anti-Tumor Effects of Pan-HER Inhibitor Varlitinib on Cholangiocarcinoma Cell Lines</p>
... EGFR inhibitor in patients with non-small cell lung ...EGFR inhibitor with a downstream effector molecule inhi- bitor such as PI3K inhibitor or MEK inhibitor, can over- come this ...PI3K ... See full document
16
Abnormalities in alternative splicing of angiogenesis-related genes and their role in HIV-related cancers
... Epstein–Barr virus is a human c-herpes virus that has been associated with NHL. The major viral oncogene expressed in EBV-associated lymphoma is latent membrane protein-1 (LMP1). This is a 62-kDa integral membrane ... See full document
17
Bifurcation analysis for a free-boundary tumor model with angiogenesis and inhibitor
... there exist symmetry-breaking solutions bifurcating from the radially symmetric solution. While, if the inhibitor is present (β = 0) and the boundary conditions (1.4) and (1.5) are replaced by the boundary ... See full document
13
An in vivo comparison of accuracy of two electronic apex locators in determining working length using stainless steel and nickel titanium files
... In vivo studies that use EALs to determine the WL simulate the clinical condition in contrast to ex vivo studies where relation to clinical situation might not be ... See full document
8
Peptide-coated gold nanoparticles for modulation of angiogenesis in vivo
... of angiogenesis: P1 (KPQPRPLS) binds to the vascular endothelial growth factor receptor-1 and promotes signal cascade activation of angiogenic genes; P2 (KPRQPSLP) does not interact with any receptor and is taken ... See full document
7
Count variation Effect on physical properties of Single jersey Cotton-elastane knittedFabric
... The kinetic and thermodynamic quantities are listed in (table 4). The values of activation energy in the presence of the inhibitor are higher than for case in the absence of it, and the largest value indicated at ... See full document
9
Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles
... In this study, biodegradable poly ( ε -Caprolactone)-poly (ethylene glycol)-poly ( ε -Caprolactone) (PCL-PEG-PCL) copolymers were synthesized. CUR-NPs were produced from the self-assembly of the copolymer, assisted by a ... See full document
10
Ex vivo and in vivo evaluation of an ultrasonic device for precise dissection, coagulation, and transection
... For burst pressure measurements, porcine carotid arter- ies of 3–5 mm diameter were selected. Arteries are chosen for burst pressure testing because they experience higher pressures than veins in vivo. During ... See full document
7
The Effects of MDMA on Brain: An in Vivo Study in Rats
... In the present study, the effects of different doses of MDMA administration on the serotonin levels in the CSF of the rats and the number of intact neurons, which reflected the[r] ... See full document
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