[PDF] Top 20 Curcumin protects against palmitic acid-induced apoptosis via the inhibition of endoplasmic reticulum stress in testicular Leydig cells
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Curcumin protects against palmitic acid-induced apoptosis via the inhibition of endoplasmic reticulum stress in testicular Leydig cells
... Background: Palmitic acid (PA) is a common saturated fatty acid that induces apoptosis in various types of cells, including testicular Leydig ...cell apoptosis may ... See full document
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Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes
... ER stress, activate the UPR and promote cell death in a great amount of cell types, such as hepatocytes [25][21] ...that palmitic acid causes obvious cell death in primary rat ...the palmitic ... See full document
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Original Article Polyenylphosphatidylcholine alleviates palmitic acid-induced apoptosis in HepG2 cells via inhibiting endoplasmic reticulum stress
... hepatocytes induced by carbon tetra- chloride and arachidonic acid, as well as inhibit stress reaction and lipid per-oxidation caused by ...mitochondrial apoptosis in Kupffer cells ... See full document
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-induced apoptosis in PC12 cells by suppressing the expression of endoplasmic reticulum stress-related proteins
... neuronal apoptosis by a mechanism which involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand ...neuronal apoptosis, suggest- ing an important role of Aβ neurotoxicity in AD ... See full document
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<p>Ox-LDL Causes Endothelial Cell Injury Through ASK1/NLRP3-Mediated Inflammasome Activation via Endoplasmic Reticulum Stress</p>
... muscle cells, and inhibit choles- terol ef fl ux, resulting in large accumulations of cholesterol in foam ...that apoptosis of macrophage-derived foam cells occurs in the plaques of most patients with ... See full document
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Taurine protection of PC12 cells against endoplasmic reticulum stress induced by oxidative stress
... oxidative stress trigged by different inducers, such as age-related retinal degeneration, a high cholesterol diet, lead poisoning and nitric oxide ...function against oxidative stress, the mechanism ... See full document
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Original Article Curcumin protects mesenchymal stem cells against oxidative stress-induced apoptosis via Akt/mTOR/p70S6K pathway
... with curcumin, and the specific Akt inhibitor perifosine largely reversed the effects of ...mitochondrial apoptosis of BM-MSCs was closely bound up with the inactivation of Akt/ mTOR/p70S6k ...of ... See full document
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Original Article Calcium homeostasis disruption and endoplasmic reticulum stress mediats ischemia/reperfusion-induced PC12 cells apoptosis
... PC12 cells was deter- mined by ATPase/GTPase Activity Assay Kit (sigma, ...models, cells were harvested, homogenized with ice cold assay buffer and centrifuged at 14000 rpm for 10 ... See full document
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Original Article Ischemic preconditioning protects motor neurons against ischemic injury by inducing endoplasmic reticulum stress, upregulating GRP78 and inhibiting caspase-12 activation
... protection against ischemic injury in the spinal ...expression induced by preemptive IPC contributed to the protection of cardiomyocytes against ischemic injury ... See full document
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Derlin 1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress induced apoptosis
... solid-tumor cells and can become growth-limiting ...cellular stress-responsive path- ways, including cytoprotective or cytodestructive ...induce endoplasmic reticulum (ER) stress and ... See full document
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Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors
... hematological cells, but appeared themselves prone to the development of drug resistance by mechanisms including PSMB5 mutations [41, ...BTZ-resistant cells harboring PSMB5 mutations handle proteolytic ... See full document
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A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress
... mitochondria-dependent apoptosis has been described as a pivot in the downstream signaling cascade of ROS during apoptotic process ...in apoptosis involving mitochondrial dysfunction [41]. Cell ... See full document
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Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress
... ER stress caused by accumulation of unfolded or misfolded proteins ...XBP1s induced by focal cerebral ischemia, but not affect CHOP expression ...and apoptosis marker cleaved caspase-3 reduced in ... See full document
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Chlorogenic acid protects PC12 cells against corticosterone-induced neurotoxicity related to inhibition of autophagy and apoptosis
... CORT induced autophagy and neurotoxicity in PC12 cells To investigate the induction effect of CORT on au- tophagy and neurotoxicity of PC12 cells, cells were treated with different ... See full document
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Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells
... MCF-7 cells (Additional file 1: Figure ...ER stress in human breast can- cer ...MDA-MB-231 cells was up-regulated in 6 ...ER stress inhibi- tor, on α-mangostin treated and untreated ... See full document
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<p>Monosialoganglioside protects against bupivacaine-induced neurotoxicity caused by endoplasmic reticulum stress in rats</p>
... method. After blocking endogenous peroxidase activity with 3% H 2 O 2 for 15 minutes, the sections were permeabilized with 0.3% Triton X-100 (Solarbio, Beijing, China) for 10 minutes and incubated with 5% normal goat ... See full document
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Curcumin Ameliorates Furazolidone Induced DNA Damage and Apoptosis in Human Hepatocyte L02 Cells via Inhibiting ROS Production and Mitochondrial Pathway
... L02 cells were pretreated with curcumin at ...the curcumin control) Cells in the negative control group were treated with ...from cells were extracted using TRlzol® reagent (Life ... See full document
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Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure
... the endoplasmic reticulum (ER), which activates the unfolded protein response ...ER stress in tumor initiation and progression is ...ER stress, we applied tauroursodeoxycholic acid ... See full document
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Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells
... rapidly induced by IFNγ + IL-1β, with maximal induc- tion at 1 h ...IL-1β induced STAT2 phosphoryl- ation, with maximal effect at 1-2 h ...EndoC-β1 cells, IFNα activates the transcription fac- tors ... See full document
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Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes
... Cell apoptosis was detected by Hoechst 33342 ...with palmitic acid elevated cell ...the endoplasmic reticulum stress markers — glucose regulated protein 78 (GRP78), C/EBP ... See full document
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