[PDF] Top 20 Current and emerging treatment strategies for breast cancer-induced bone loss

... Clinicians now have medical evidence to guide treatment decisions in the management of bone loss. Among the bispho- sphonates studied, zoledronic acid has the most potent effect on the preservation ... See full document

... A 3-year-old boy is referred for evaluation of developmental delay. He was born after an unremarkable pregnancy at term, with no complications. His development was normal during the first year. Although he is generally ... See full document

... of bone structure (including posterior vertebral body wall) and quan- tify height loss when ...with cancer, several fractures of various ages may commonly coexist, hindering identification of ... See full document

... The TGF-β family consists of at least five highly conserved polypeptides, with TGF-β1, -β2 and -β3 being the principal mammalian forms. TGF-β1 and -β2 are among the most important stimulators of collagen and proteoglycan ... See full document

... of treatment for actinic keratoses is the use of cryosurgery with liquid nitrogen as the ...of treatment where thin lesions are destroyed with a 5–7 second freeze ... See full document

... non-tumor-containing bone? Th ere are many suspected factors, such as microfractures, loss of mechanical loading, hormones, cytokines, calcium levels and infl ...the current discussion, cancer ... See full document

... Abstract: Pericarditis is a common disorder that has multiple causes and presents in various primary-care and secondary-care settings. It is diagnosed in 0.1% of all hospital admissions and in 5% of emergency room visits ... See full document

... in breast cancer have improved survival but consequently increase the relevance of late ...on bone health. However, investigation and management of cancer treatment-induced ... See full document

... osteolytic bone metastases in animal tu- mor models, demonstrating that the addition of early bisphosphonate, clodronate in this case and radiation therapy, significantly improved the density and bone mi- ... See full document

... Maintaining bone health is important for patients with breast cancer (BC), the most commonly diagnosed cancer in American ...Indeed, bone loss is common throughout the BC disease ... See full document

... uterine cancer side effects and improved disease-free ...of breast cancers are ER + ...of breast cancer from prevention in high-risk populations to neoadjuvant therapy in advanced-stage ... See full document

... Abstract: Cancer therapy-induced bone loss (CTIBL) is a form of secondary osteoporosis associated with systemic chemotherapy and hormonal ablation ...and treatment of CTIBL is an ... See full document

... of cancer recurrence in ...some cancer treatment-related side effects and improve ...for cancer survivors may be necessary, similar to cardiac rehabilitation exercise programs for cardiac ... See full document

... Colorectal cancer is the second most common cancer in Hong Kong and its inci- dence is rising in economically developed Chinese cities, including Hong Kong and ...colorectal cancer syndromes and ... See full document

... the treatment of bone metastases compared with ibandronic ...latest cancer therapy guidelines recommend zoledronic acid for the early stages of MM with the recommended dose of 4 mg IV in 15 minutes ... See full document

... Besides the inherent differences in mouse models and human subjects, another possible reason for the high drug attrition rates in late stage SCLC clinical studies could be due to the fact that it has been challenging to ... See full document

... 52. Santini, D., Schiavon, G., Vincenzi, B., Gaeta, L., Pantano, F., Russo, A., Ortega, C., Porta, C., Galluzzo, S., Armento, G., La Verde, N., Caroti, C., Treilleux, I., Ruggiero, A., Perrone, G., Addeo, R., Clezardin, ... See full document

... for treatment of metastatic bone dis- ease (120 mg subcutaneously every 4 ...spine bone mineral density at 12 ...stage breast cancer patients where the primary endpoint is the time to ... See full document

... and treatment of bone metastasis requires various types of measures, specialists and ...and treatment, a multidisciplinary team approach is ...with bone metastases mainly from 2003 to 2013, ... See full document

... scan breast tumor. The patient underwent a fine needle aspirate of the breast lesion that revealed an estrogen receptor positive ...or bone lesions, although lymphadenopathy was ... See full document