[PDF] Top 20 Current options for the treatment of optic neuritis

... ing treatment, without having a large study like the ONTT, there are only case series reports to help guide ...common treatment option is to use high- dose steroids (3–5 days of 1000 mg IV ... See full document

... Abstract: Acute optic neuritis (ON) has various etiologies. The most common presentation is inflammatory, demyelinating, idiopathic, or “typical” ON, which may be associated with multiple sclerosis. This ... See full document

... Posteriorly optic nerve is surrounded by annulus of Zinn and orgin of four rectus ...to optic nerve sheath and accounts for pain on ocular movements seen in retrobulbar ...the optic nerve before ... See full document

... Calcitonin was the first antiresorptive agent to be used for PDB (generally at daily subcutaneous injections for several months) and is still approved for the treatment of PDB. The synthetic polypeptide hormone of ... See full document

... TOS was performed in patients and age- and sex-matched con- trols by 2 expert sonographers (P.L. and L.C.). VEP were per- formed only in patients, to avoid discomfort due to needle elec- trode placement in healthy ... See full document

... of optic nerve. Optic neuritis may be unilateral but frequently ...Parainfectious optic neuritis whether viral or bacterial may occur in patients with no evidence of neurologic ... See full document

... and treatment duration. Often, clinical presentation of optic neuritis is the main factor for the decision maker for initiat- ing and duration of acute ... See full document

... [31], implying that the axonal loss measurable with OCT is clinically relevant, and validating its role as a surrogate marker of the pathology underpinning MS progression. Interestingly, RNFL thinning appears to progress ... See full document

... 73.3% of the patients (30 eyes) have visual acuity 6/60 or worse during presentation. This included 70.0% (20 eyes) who suffered attacks of papillitis, and 83.4% (10 eyes) with signs of retrobulbar ON. All adult patients ... See full document

... of optic neuritis, low dose oral steroid of 1 mg/km/day was still the recommended treatment of up to 65% of neurologist and ...a treatment option before the information session may have ... See full document

... All of our NMO patients had normal cranial MRI results and all had relapsing NMO. Among the four patients that met the criteria for NMO, three were positive for NMO antibodies in their serum. The absence of antibodies in ... See full document

... fluid with 288 white cells (98% lymphocytes), elevated proteins (94 mg/dl) and normal glucose. Gram stain showed no organism and bacterial, viral, fungal and tuberculosis cultures were negative. CSF VDRL was nega- tive. ... See full document

... intravenous treatment with corticosteroids, which may quicken the healing of the optic nerve, is often recommended, but it does not have a significant effect on the visual acuity at one year, when compared ... See full document

... CONCLUSION ON is a common presenting symp- tom in pediatric CNS demyelinating disorders. Clin- ical symptoms may be dramatic, especially in younger children, with severe decreases in visual acuity in more than half of ... See full document

... All our patients in this study were treated with intra venous methyl prednisolone 250mg four times daily for three days followed by oral prednisolone 1mg per kg body wt for 11 days (As per ONTT guidelines). Majority of ... See full document

... traditionally used as the treatment of choice for PDA. Its use, however, has waned due to the recognition of renal, cerebral, and gastrointestinal complications associated with the admin- istration of this drug. ... See full document

... We reviewed the literature on the current epidemiologic data, pathophysiology, and classic and emerging therapeutic options for Chagas’ disease. Articles were selected from a computerized literature search ... See full document

... persistent optic nerve head ...right optic nerve and the right aspect of the optic chiasm, extending to the right optic tract up to the lateral geniculate nucleus (figure ...the optic ... See full document

... wild-type and mutant ALK were sensitive to perifosine. The role of perifosine in overcoming chemoresistance was tested in a TrkB-expressing neuroblastoma cell line TB3 which demonstrates BDNF-induced Akt activation. ... See full document

... Other options include dermabrasion or alexandrite laser; however, cost must be considered with these treatments as well the potential for post-inflammatory ... See full document