[PDF] Top 20 Cyclooxygenase 2 and selenium in breast cancer
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Cyclooxygenase 2 and selenium in breast cancer
... of breast cancer patients with bone metastases and/or liver metastases, and was more effective than AST and GGT in distinguishing patients with relapse from those without [11] and with Nathaniel et ...in ... See full document
7
Suspension state promotes metastasis of breast cancer cells by up-regulating cyclooxygenase-2
... BCCs: breast cancer cells; B-RAF: B-Raf proto-oncogene; CaN: calcineurin; COX-2: cyclooxygenase-2; CsA: cyclo- sporine A; CTCs: circulating tumor cells; CXB: celecoxib; CytoD: ... See full document
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Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells
... and cancer has generated intense interest in Cyclooxygenase-2 (COX-2) that is the rate-limiting enzyme in the metabolic conversion of arachidonic acid (AA) into various prostaglandins (PGs) ... See full document
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Cancer/stroma interplay via cyclooxygenase 2 and indoleamine 2,3 dioxygenase promotes breast cancer progression
... 33. Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, Thompson CB: The common feature of leukemia-associated ... See full document
14
A novel role for cyclooxygenase 2 in regulating vascular channel formation by human breast cancer cells
... human breast cancer cells expressing high and low levels of COX-2 to form vascular channels on three-dimensional matrigel cultures, and to assess the effect of therapeutically targeting COX-2 ... See full document
11
Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo
... Celecoxib may exert an inhibitory effect on the en- hanced radiation-induced G2/M arrest in the COX-2- overexpressing cells. This effect may allow the arrested cells to enter mitosis and die after radiation [31]. ... See full document
8
Genetic polymorphisms in the cyclooxygenase 2 gene, use of nonsteroidal anti inflammatory drugs, and breast cancer risk
... Genomic DNA was extracted [41] by standard RNase/protei- nase K and phenol/chloroform treatment and genotyped by a fluorescence polarization method, using a commercial Acyclo- Prime™-FP SNP Detection Kit obtained from ... See full document
10
Cross talk between SIM2s and NFκB regulates cyclooxygenase 2 expression in breast cancer
... various breast cancer cell ...parental breast cancer cell ...(cm 2 ). B. %COX-2 (M+S) compared to tumor size (cm 2 ... See full document
12
Cyclooxygenase-2 in tumor-associated macrophages promotes metastatic potential of breast cancer cells through Akt pathway
... malignant breast cancer cells. Therefore, the high expression of COX-2 in TAMs should be induced by the interaction between TAMs and cancer cells in our ...in breast cancer ... See full document
11
Cyclooxygenase 2–dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer
... To evaluate the role of COX-2 activity in expansion of the lym- phatic vasculature during normal postpartum mammary gland involution in vivo, postpartum mice were fed celecoxib (CXB) dur- ing involution as ... See full document
13
The Role of MicroRNAs in Cyclooxygenase-2 Mediated Breast Cancer Progression
... Figure 11. Cells derived from tumorspheres have a higher COX-2 expression in comparison to cells grown as a monolayer. Cells were grown in 6-well low attachment plates at 2x10 4 cells/ml and allowed to form ... See full document
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p130Cas/Cyclooxygenase 2 axis in the control of mesenchymal plasticity of breast cancer cells
... in breast tumors expressing high levels of p130Cas and Cox-2, the same strategy already proposed in HER2-positive trastuzumab-resistant tumors to over- come trastuzumab resistance ... See full document
12
Reduction in cancer risk by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors
... the breast, colon, prostate, and ...four cancer sites revealed that regular intake of 325 mg aspirin, 200 mg ibuprofen, or standard dosages of coxibs (200 mg celecoxib or 25 mg rofecoxib) produced risk ... See full document
6
Reduced Risk of Human Lung Cancer by Selective Cyclooxygenase 2 (Cox-2) Blockade: Results of a Case Control Study
... American Cancer Society estimates that more than ...invasive cancer will be diagnosed during 2006 in the United States, and more than 564,000 Americans will die from cancer ...considered, ... See full document
7
Use of Propolis in Cancer Research
... COX;- cyclooxygenase COX-1;- cyclooxygenase-1 COX-2;- cyclooxygenase-2 EEP-; ethanolic extract of propolis GPE;- grape polyphenols HUVEC;- human umbilical vein endothelial cells IFNγ;- ... See full document
22
Clinical value of detecting IQGAP3, B7-H4 and cyclooxygenase-2 in the diagnosis and prognostic evaluation of colorectal cancer
... As a novel member of IQGAPs family, a host of researches were conducted to explore the role of IQGAP3 in cancers. IQGAP3 was previously proved to be involved in cell proliferation, adhesion, migration and metasta- sis in ... See full document
14
Inflammation and breast cancer Cyclooxygenase/prostaglandin signaling and breast cancer
... of cyclooxygenase-2 (COX-2), a key enzyme in eicosanoid ...invasive breast carcinoma and at a higher frequency in preinvasive ductal carcinoma in situ tumors, Extensive pharmacologic and ... See full document
9
Modulation of CXCR3 ligand secretion by prostaglandin E2 and cyclooxygenase inhibitors in human breast cancer
... human breast cancer iden- tifying CXCL9, rather than CXCL10 or CXCL11, as a potential biomarker for diagnosis of breast cancer and therapy response, suggestive of its protective role in ... See full document
14
Promoter methylation regulates cyclooxygenase expression in breast cancer
... both breast and colon human cancer cell lines ...murine breast tumors employ a similar mechanism of COX-2 gene regulation, we used methylation-specific PCR to examine the methylation pattern ... See full document
6
Current biomarkers of canine mammary tumors
... human breast cancers (HBC), human biomarkers of HBC are also detectable in cases of ...miRNAs, cancer stem cells, and circulating tumor cells, as well as mutations of the breast cancer 1 gene ... See full document
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