[PDF] Top 20 Cytokine expression & TGF-beta signaling in cervical cancer
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Cytokine expression & TGF-beta signaling in cervical cancer
... in cervical cancer is HLA class I ...as cervical- cancer, development of a powerful immune response could be hindered since viral antigen is not or insufficiently ...Low expression of ... See full document
157
<p>G3BP1 activates the TGF-β/Smad signaling pathway to promote gastric cancer</p>
... the expression of G3BP1 in GC cell ...the signaling pathway through which G3BP1 plays a role in ...Ras, TGF- β /Smad, Src/FAK, and p53 signaling ... See full document
8
TGFβ signaling supports survival and metastasis of endometrial cancer cells
... endometrial cancer cell line HEC-1-A is TGF β ...of TGF β signaling in their proliferation and ...The expression of DNRII or DNRII-EGFP was detected with Western immunoblotting as shown ... See full document
10
JUNB governs a feed-forward network of TGF beta signaling that aggravates breast cancer invasion
... after TGF  (5 ng / ml) ...h TGF  (5 ng / ml) treatment was attenuated more than 50% with siJUNB treatment are colored ...of expression changes of SMAD2 / 3 target genes after manipulation of JUNB ... See full document
16
Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions
... regulate signaling pathways involved in EMT Many miRNAs influence the EMT process by targeting the expression of specific ligands, receptors, and signaling pathways (Figure ...in ... See full document
11
<p>HOXD9 Activates the TGF-β/Smad Signaling Pathway to Promote Gastric Cancer</p>
... in cervical cancer cells, but not in normal cervical ...the expression of HOXD9 protein in samples through IHC and found that over 60% of ESCC cells were stained for HOXD9 protein to varying ... See full document
10
Celastrol inhibits colorectal cancer through TGF-β1/Smad signaling
... their expression in human colon cancer tissues was signally increased (Figure ...of TGF- β 1 and its receptors (Figures 3 and ...colon cancer tissues (Figure ...of TGF- β 1 ... See full document
10
Original Article Activation of major vault protein by TGF-beta is associated with advanced malignancy and poor prognosis in breast cancer
... MVP expression. We here characterized that TGF-β signaling was partially involved in regu- lating MVP ...expression. TGF-β has long been recognized as a multifunctional cytokine ... See full document
8
SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis
... in cancer devel- opment and ...gastric cancer, and its upregulation is associated with lymph node metastasis and poor ...gastric cancer metastasis and the underlying mechanism remain ...gastric ... See full document
12
Transforming Growth Factor – β and Glioma
... regulatory cytokine secreted by various types of cell such as stromal cell, immune cells and tumor ...cells. Signaling of TGF-β plays an important role in proliferation, differentiation and apoptosis ... See full document
5
Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions
... CD73 expression [55]. The involvement of TGF-β in the regulation of CD39+ and CD73+ expression in various immunosuppressive cell types has also been ...CD73 expression in immunosuppressor CD4+ ... See full document
14
The Effect of Cytokines on MicroRNA Expression in TW01 Nasopharyngeal Carcinoma Cells
... Presence of IL-6 caused up-regulation of 67% miRNAs in TW01-LMP1 as compared to control. Eight miRNAs; namely, miR-15b, miR-155, miR-16, miR-215, miR-23b, miR-25, miR-9 and miR-98 were significantly up-regulated with ... See full document
12
TINAGL1 promotes hepatocellular carcinogenesis through the activation of TGF-β signaling-medicated VEGF expression
... VEGF signaling pathways participated in the accelerating effect of TINAGL1 in HCC ...ng/mL TGF- β (R&D Systems ...of TGF- β /Smad3 in TINAGL1-overexpressing HCC-LM3 cells, 10 µM SB431542 or 1 µM ... See full document
9
A Tale of Breast Cancer, Behavior and Brains as Affected by Diet and Claudins
... The matrix metalloproteinases (MMPs) are members of a family of at least 20 proteolytic enzymes that contain a zinc ion at their active sites and can degrade collagen, elastins, and other components of the ECM. ... See full document
156
Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells
... the expression of the TGFs were present, equivalent binding was observed in the different intestinal cell populations when assessed with 125I-TGF beta and 125I-EGF (TGF ...was TGF ... See full document
7
CRISPR mediated reactivation of DKK3 expression attenuates TGF β signaling in prostate cancer
... the expression of these genes is regulated by gene promoter methylation in PCa, q-RT-PCR analysis was carried out to measure mRNA expression in PC3 cells treated with ...the expression of the same ... See full document
20
The role of TGF-β/SMAD4 signaling in cancer
... between TGF-β/SMAD4 signaling pathway and MAPK (mitogen-activated protein kinase), PI3K/AKT (phosphatidylinositol-3 kinase/AKT) and WNT/β-catenin ...canonical TGF-β/SMAD4 signal initiates from the ... See full document
13
Original Article Metastasis-associated colon cancer-1 is a novel prognostic marker for cervical cancer
... Immunohistochemical analysis was done to study altered protein expression in 104 cervial cancer tissues. In brief, paraffin-embedded specimens were cut into 5 um sections and baked at 60°C for 3 h followed ... See full document
6
STAT3 and STAT1 mediate IL 11–dependent and inflammation associated gastric tumorigenesis in gp130 receptor mutant mice
... the indicated antibodies. Each lane represents tissue from an individual mouse. Densitometric quantitation of IL-11 in each of 3 representative samples per genotype was performed and normalized against ERK1/2 protein ... See full document
13
The multi-faceted functioning portrait of LRF/ZBTB7A
... p53 expression and phosphorylation [37, 38] indi- cating that LRF/ZBTB7A loss-of-function indirectly inhibits aerobic glycolysis and enhances OXPHOS, com- promising thus the Warburg effect in cancer ... See full document
14
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