[PDF] Top 20 Roles for the Cytoplasmic Tails of the Fusion and Hemagglutinin-Neuraminidase Proteins in Budding of the Paramyxovirus Simian Virus 5
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Roles for the Cytoplasmic Tails of the Fusion and Hemagglutinin-Neuraminidase Proteins in Budding of the Paramyxovirus Simian Virus 5
... of budding on the plasma membrane of infected ...the cytoplasmic tails of surface glycoproteins and the matrix (M) ...the paramyxovirus simian virus 5 (SV5), the ... See full document
14
Role of the Cytoplasmic Tail Amino Acid Sequences of Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein in Virion Incorporation, Cell Fusion, and Pathogenicity
... and neuraminidase activity, and the transmembrane do- main anchors to viral envelopes ...The cytoplasmic tail domain contains 26 highly conserved amino acids whose func- tions are not ...the ... See full document
6
Roles of the Fusion and Hemagglutinin-Neuraminidase Proteins in Replication, Tropism, and Pathogenicity of Avian Paramyxoviruses
... disease virus (NDV), representing avian paramyxo- virus serotype 1 (APMV-1), cause respiratory and neurological disease in chickens and other species of ...the fusion (F) and hemagglutinin- ... See full document
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Requirements for Budding of Paramyxovirus Simian Virus 5 Virus-Like Particles
... and budding of membranes to release ...stomatitis virus and Ebola virus), the viral matrix (M) protein contains all of the information needed for budding, since virus-like particles ... See full document
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Role of Matrix and Fusion Proteins in Budding of Sendai Virus
... of budding. We investigated the roles of three Sendai virus (SV) membrane proteins in the production of virus-like ...(M) proteins from cDNA induced the budding and ... See full document
8
Down-regulation of paramyxovirus hemagglutinin-neuraminidase glycoprotein surface expression by a mutant fusion protein containing a retention signal for the endoplasmic reticulum.
... parainfluenza virus type 3 (HPIV3) fusion (F) and hemagglutinin-neuraminidase (HN) glyco- proteins are the principal components involved in virion receptor binding, membrane ... See full document
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Hemagglutinin-Neuraminidase-Independent Fusion Activity of Simian Virus 5 Fusion (F) Protein: Difference in Conformation between Fusogenic and Nonfusogenic F Proteins on the Cell Surface
... The fusion (F) protein of simian virus 5 (SV5) strain W3A is known to induce cell fusion in the absence of hemagglutinin-neuraminidase (HN) ...cell fusion only when ... See full document
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Quantitative measurement of paramyxovirus fusion: differences in requirements of glycoproteins between simian virus 5 and human parainfluenza virus 3 or Newcastle disease virus.
... for paramyxovirus-mediated cell fusion, the fusion (F) and hemagglutinin- neuraminidase (HN) glycoproteins of simian virus 5 (SV5), human parainfluenza virus ... See full document
9
A Histidine Switch in Hemagglutinin-Neuraminidase Triggers Paramyxovirus-Cell Membrane Fusion
... Sendai virus (SeV), Newcastle disease virus (NDV), human parainfluenza virus type 1 (hPIV1) to hPIV4, and several other enveloped animal and human viruses of the Paramyxoviridae family share a common ... See full document
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Mutations in the Cytoplasmic Domain of a Paramyxovirus Fusion Glycoprotein Rescue Syncytium Formation and Eliminate the Hemagglutinin-Neuraminidase Protein Requirement for Membrane Fusion
... essential roles in fusion ...for fusion was shown by mutational analysis (34, 41) and also by using peptide analogues which inhibit fusion, possibly because they interfere with the ... See full document
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Multifaceted Sequence-Dependent and -Independent Roles for Reovirus FAST Protein Cytoplasmic Tails in Fusion Pore Formation and Syncytiogenesis
... enveloped virus fusion protein CTs also remains elusive, although several models have been proposed to ex- plain how CTs might influence membrane fusion ...Env proteins of retrovi- ruses such ... See full document
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Fusion Promotion by a Paramyxovirus Hemagglutinin-Neuraminidase Protein: pH Modulation of Receptor Avidity of Binding Sites I and II
... and 5) and in an epithelial cell fusion assay ...cell fusion experiments in Fig. 5 D216R HN shows no detectable promotion of cell fusion at pH ...variant’s neuraminidase defect ... See full document
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Chimeric Bovine Respiratory Syncytial Virus with Attachment and Fusion Glycoproteins Replaced by Bovine Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase and Fusion Proteins
... RNA virus envelope protein interactions is that the matrix proteins specifically in- teract with cytoplasmic tails of the envelope glycoproteins (31) which are incorporated into the host ... See full document
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Involvement of the Cytoplasmic Domain of the Hemagglutinin-Neuraminidase Protein in Assembly of the Paramyxovirus Simian Virus 5
... HN cytoplasmic tail-truncated SV5 recombinants from cloned ...HN cytoplasmic tail truncations have on the replication and assem- bly of SV5, recombinant viruses were generated with a recently established ... See full document
10
Bimolecular Complementation of Paramyxovirus Fusion and Hemagglutinin-Neuraminidase Proteins Enhances Fusion: Implications for the Mechanism of Fusion Triggering
... a fusion protein (F). Like other class I viral fusion proteins, F is expressed as a prefusion metastable protein that undergoes a refolding event to induce ...the cytoplasmic tails of ... See full document
12
Induction of Apoptosis by Paramyxovirus Simian Virus 5 Lacking a Small Hydrophobic Gene
... important proteins in the TNF-␣ signaling pathway were ...SV5 virus-infected cells induced CPE in L929 cells ...from virus-infected cells to induce p65 degrada- tion was ... See full document
13
The Cytoplasmic Tails of Uukuniemi Virus (Bunyaviridae) GN and GC Glycoproteins Are Important for Intracellular Targeting and the Budding of Virus-Like Particles
... UUK virus minigenome plasmid containing the noncoding regions from the M segment, flanking the reporter gene for chloramphenicol acetyltransferase (CAT) ... See full document
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Membrane Fusion Promoted by Increasing Surface Densities of the Paramyxovirus F and HN Proteins: Comparison of Fusion Reactions Mediated by Simian Virus 5 F, Human Parainfluenza Virus Type 3 F, and Influenza Virus HA
... of fusion (18), though in experi- ments using liposome fusion assays with cells lines expressing the H2 subtype HA a difference in fusion extent was observed (20), suggesting assay-to-assay ... See full document
9
Modification of the Cytoplasmic Domain of Influenza Virus Hemagglutinin Affects Enlargement of the Fusion Pore
... the cytoplasmic tail pro- mote pore dilation? Based on the observation that GPI-an- chored HA causes the formation of a metastable hemifusion diaphragm after triggering the conformational change of the ectodomain ... See full document
9
Mutations in the Ectodomain of Newcastle Disease Virus Fusion Protein Confer a Hemagglutinin-Neuraminidase-Independent Phenotype
... (Fig. 5), the syncytium formation ...the fusion promotion impairment of the Q454A mutant could be reversed at elevated temperatures, we performed dye transfer fusion assays at ... See full document
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