[PDF] Top 20 Delayed Diagnosis of Critical Congenital Heart Defects: Trends and Associated Factors

... considered critical if corrective surgery or interventional catheterization was performed, if palliative care was ad- ministered, and/or if the infant died of defect-related causes within the fi rst year of ... See full document

... a delayed diagnosis of a CCHD and thus would be potentially preventable with ...just delayed diagnoses), relied on multiple assumptions, and were limited by their amount of clinical ... See full document

... There are many factors to consider when determining the optimal screening algorithm. The first issue is the balance of sensitivity and specificity. Screening programs typically aim for very high sensitivity, but ... See full document

... the factors most strongly associated with survival across all levels of ...with critical univentricular CHDs, few other risk factors were associated with survival, with the exception of ... See full document

... ongenital heart disease (CHD) remains one of the most common forms of severe congenital ...fetal diagnosis, have signifi- cantly decreased the age of diagnosis and referral of neonates and ... See full document

... basic trends in epidemiology of con- genital heart defects ...Twelve critical CHDs (causing death or requiring invasive proce- dures before 28 days of life) were ...Prenatal diagnosis ... See full document

... ICD-9-CM diagnosis code on the birth hospital discharge record or, if applicable, on a subsequent hospitalization determined to be a transfer from the birth ... See full document

... is associated with a number of congenital ...abnormalities, congenital heart defects of the endocardial cushions, clinodactyly of the fifth finger and mental retardation and several ... See full document

... first heart field (FHF) and second heart field (SHF) cardiac progen- ...After heart tube formation, while a strong expression of Hnrnpa1 was maintained in the splanchnic mesoderm, which was partially ... See full document

... other congenital abnormality (case in- fants) and 3982 women (69% of eligible participants) who had live-born singleton infants without any birth defects (control infants) were enrolled in the NBDPS (Fig ... See full document

... In this study, we found that neonates with CCHD were or would have been detected clinically within sev- eral hours of birth. Twenty-seven neonates with CCHD were detected as a result of prenatal ultrasound abnor- ... See full document

... of their location in the hospital or pre- natal diagnosis and any infant that fails the screening protocol should be re- ported to the NJBDR. Our fi ndings also highlight the need to clarify and em- phasize the ... See full document

... clinical diagnosis of WBS, fluorescent in situ hybridization (FISH) was applied on metaphase spreads using the dual color locus specific identifier WBS region probe (Vysis probe) that hybridizes to the ELN and ... See full document

... had congenital heart surgery and were younger than 18 years were identified using Interna- tional Classification of Diseases, Ninth Revision, Clinical Modification ...for Congenital Heart ... See full document

... tube defects, congenital heart defects, and oral clefts, several studies were avail- able, enabling us to calculate pooled estimates based on ...birth defects, al- lergic diseases, and ... See full document

... An institutional review board-approved retrospective study was carried out on all newborns with prenatally diagnosed intrathoracic masses delivered between 2009 and 2016 at the Neonatal Intensive Care Unit of University ... See full document

... with congenital heart defects(CHDs) continues to improve with advancing surgical techniques; however, lack of information about modifiable risk factors for malformations in cardiovascular ... See full document

... tube defects (n = 9) and oral clefts (n = 5), due to statistical hetero- geneity, whereas a fi xed-effects meta- analysis was conducted for studies on congenital heart defects (n = ...cantly ... See full document

... The combination of qualitative and quantitative ana- lysis used is here a strength. The qualitative methods used were content analyses of participants “think aloud” notes/protocols during a pre- and post-course test, an ... See full document

... not associated with the pres- ence of ...been associated with ...were associated with higher prevalence of any form of CHD ...not associated with a risk of CHD ... See full document