[PDF] Top 20 Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells
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Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells
... the cell cycle ...proliferating cells of various hematological malignancies but is normally expressed in the slowly proliferating cells of chronic malignant hematological diseases ...and ... See full document
8
Original Article Apigenin inhibits proliferation of human chondrosarcoma cells via cell cycle arrest and mitochondrial apoptosis induced by ROS generation-an in vitro and in vivo study
... chondrosarcoma cells. Cell viability, Clone for- mation, Cell cycle, typical apoptotic morphological changes were identified by optical microscopy, Hoechst staining, and transmission electron ... See full document
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Genetically engineered drug rhCNB induces apoptosis and cell cycle arrest in both gastric cancer cells and hepatoma cells
... rhCNB inhibits the growth of tumor both in vitro and in vivo in another cell ...hepatoma cell lines Bel-7402 and HepG2 to different concentrations of rhCNB treatment for 24 ...markedly ... See full document
9
<p>Diosmetin Inhibits Cell Proliferation, Induces Cell Apoptosis and Cell Cycle Arrest in Liver Cancer</p>
... anti-tumor, cell cycle arrest and cell apopto- sis have been widely ...the cell viability, apop- tosis and cell cycle arrest in human hepatoma HepG2 cells ... See full document
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<p>HOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1</p>
... We then explored the molecular mechanism through which HOXA10 knockdown enhanced p53 acetylation. Previously, HDAC1 has been demonstrated to directly bind to p53, which deacetylates p53 and downregulates p53 functions. ... See full document
12
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1)
... inducing cell cycle arrest and promoting apoptosis are two effective approaches to inhibit cell ...Normal cell cycle process is the key mechanism for cell ... See full document
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Original Article TRIM66 knockdown inhibits cell growth, but induces cell cycle arrest and apoptosis of hepatocellular carcinoma cells
... the proliferation of HCC cells in vitro and the growth of xenograft tumors in ...HCC cells significantly induced cell arrested in G0/ G1 phase and cell ...of cell ... See full document
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The microtubule targeting agent PBOX 15 inhibits integrin mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells
... rapidly inhibits integrin-induced T-cell migration (24) allowed us to postulate that PBOX-15 may potentially inhibit cell homing and mobility, and hence, the metastatic potential of ALL ...SD-1 ... See full document
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Profound Inhibitory and Apoptotic Effects of Histone Deacetylase Inhibitor Valproic Acid on Different Cancers
... (HCC) cells, VPA induces histone H4 acetylation and suppresses HDAC4 by which inhibits cell growth inhibition and induces cell cycle arrest and apoptosis ... See full document
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Original Article Triptolide inhibits lipopolysaccharide-induced proliferation, induces apoptosis and causes cell cycle arrest of human mesangial cells in vitro
... (LPS)-induced proliferation of human mesangial cells in vitro and the underlying ...sangial cell proliferation was detected by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium ... See full document
11
Role of scutellarin in human cancer—A review
... Scutellarin induces apoptosis and cell cycle arrest and inhibits proliferation and progression of a wide spectrum of human cancer ... See full document
5
Original Article Salidroside induces apoptosis via ERK1/2 in human leukemia K562 cells
... the apoptosis of leuke- mia [26, ...K562 cells. Sun et al. found that salidroside inhibits migration and invasion of human fibro- sarcoma HT1080 cells via inhibiting the activa- tion of ERK1/2 ... See full document
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Lupeol inhibits growth and migration in two human colorectal cancer cell lines by suppression of Wnt–β-catenin pathway
... viability, apoptosis, cell- cycle distribution, and migration of colorectal cancer cell lines and its molecular ...cancer cell lines: SW480 and HCT116. These cells were treated ... See full document
13
Inverse agonist of estrogen-related receptor α suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways
... There is an urgent clinical need for targeted therapy approaches for triple- negative breast cancer (TNBC) patients. Increasing evidences suggested that the expression of estrogen-related receptor alpha (ERRα) was ... See full document
14
Expressions of Long Non Coding RNAs in Carcinogenesis of Cervix: A Review
... epigenetically inhibits tumor suppressors CDKN2A (p16) and CDKN2B (p15), and in doing so it plays a substantial role in cellular proliferation and se- nescence [51] [52] ...in cell ... See full document
16
Marketed drugs used for the management of hypercholesterolemia as anticancer armament
... cancer cells in ...cancer cells involves the blockage of a purinergic P2X7/eHBP1/P-Rex1 ...cancer cells have been linked to the downregulation of the expression of a series of different proteins, ... See full document
19
Original Article MicroRNA-128 suppresses colorectal cancer cell proliferation through targeting LRP6
... and cell lines, and the expression of LRP6 in CRC tissues was inversely correlated with the expression of ...CRC cells led to inhi- bition of cellular ...of cell proliferation, where- as ... See full document
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B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy
... tumor cells are often subject to oxidative stress arising from the tumor environment [2] and increased consumption of reducing equivalents to support DNA synthesis [3, ...cancer cell proliferation ... See full document
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The miR155HG/miR-185/ANXA2 loop contributes to glioblastoma growth and progression
... lating apoptosis and cell ...reduced apoptosis and cell death, while genes with nega- tive expression were primarily associated with cell cycle progression and cell ... See full document
14
<p>MicroRNA-30a-3p inhibits the progression of lung cancer via the PI3K/AKT by targeting DNA methyltransferase 3a</p>
... A549 cells overexpression miR-30a-3p or siDNMT3a, resulting in inhibition of cell proliferation and cell cycle ...p38-involved cell cycle regulates expression of p21CIP1, ... See full document
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