[PDF] Top 20 Design and Development of Pharmacosomes for Oral Drug Delivery of Losartan

... composite design (CCD) of response surface methodology ...the drug concentration (X3) were selected as independent variables and the yield (%) of GP ‘present as a complex’ in the PMS was used as the ... See full document

... to design and evaluate an oral site-specific, pulsatile drug delivery system containing Lansoprazole, which can be targeted to colon in a pH and time dependent manner, to modulate the ... See full document

... experimental design methods including an artificial neutral network method 206 ...i.e., drug, osmotic pressure promoting agent rate, PEG400 content in coating solution and coating weight, were evaluated ... See full document

... with oral bioavailability of about 33% and a plasma elimination half-life ranging from ...increase oral bioavailability of Losartan by retaining the dosage form in stomach for longer period of ... See full document

... of losartan with very good physical characteristics were ...of losartan was found to be simple and ...of losartan from the development oral microcapsules will help to improve the ... See full document

... Buccal drug delivery is an alternative to per-oral and parenteral administration of ...buccal delivery system in therapy, studies have been carried out which focus on assessing the fea- ... See full document

... an oral alpha-glucosidase inhibitor, is a desoxynojirimycin derivative that delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following ... See full document

... of oral CR dosage form drop in the class of osmotic, matrix, or reservoir ...% drug release obtain by partition of the drug in to the release medium as well as polymer ...% drug release as of ... See full document

... monitoring drug release after in situ gelation in the stomach condition with an extension to monitor the release behavior after gastric ...of losartan was loaded in the dissolution vessel, using unprocessed ... See full document

... capsule drug delivery system capable of releasing drug after predetermined time ...The drug formulation is sealed inside the capsule body by an erodible ...chronotherapeutic drug ... See full document

... a drug into various films has been popular in recent ...the development of novel polymeric thin films as a drug delivery ...This drug delivery platform is being under observation ... See full document

... II oral hypoglycemic agent, which is a commonly prescribed drug management of type 2 diabetes mellitus (also known as non-insulin dependent diabetes mellitus or ...acidic drug (pKa = ...diabetic ... See full document

... During dissolution studies, it was observed that, the polymers used coat of the cellulose acetate phthalate was intact for 2 h in pH 1.2, but dissolved in intestinal pH, leaving the soluble cap of capsule, which also ... See full document

... It is evident that the original peaks of phytoconstituent and phospholipids disappear from the thermogram of complex and the phase transition temperature is lower than that of phospholipids. The acetamin and indomethacin ... See full document

... low oral bioavailability i.e. 40-85 % of an oral dose of Curcumin passes through the gastrointestinal tract unchanged, with most of the absorbed flavonoid being metabolized in the intestinal mucosa and ... See full document

... Corticosteroids and immunosuppressant are used for active disease or refractory disease. It is one of the highest used drugs in short term IBD treatment, although of their side effects, their efficacy cannot be refused ... See full document

... with oral sub-mucosa layer for prolonged ...in oral cavity. Mucoadhesive drug delivery gives rapid absorption and good bioavailability due to its considerable surface area and high blood flow ... See full document

... The peaks and patterns of the pure drug and the peaks and patterns of the combination of drug and polymers were compared with each other [4]. Preparation of ciprofloxacin hydrochloride floating tablet ... See full document

... many drug-delivery systems such as nanoparticles, microparticles, emulsions, gels, and liposomes because it is a common and model ...nanoemulsion-drug delivery system for use as an oral ... See full document

... controlled drug delivery manner where the release rate of drug output may be modulated in a previously controlled, predictable ...transdemal drug delivery of high molecular weight ... See full document