[PDF] Top 20 The DESiGN trial (DEtection of Small for Gestational age Neonate), evaluating the effect of the Growth Assessment Protocol (GAP): study protocol for a randomised controlled trial

... proposed study is that it is one of the first studies examining a program to increase emotional resilience in a residential setting and is also the only Dutch CBT program specifically adapted to adolescents with ... See full document

... the study, it is important to keep the intervention realistically close to the type of intervention that might be feasible in a low- or middle-income ...the trial team should intervene to provide extra ... See full document

... this trial will be identified by a study number only, with a master code sheet linking names, treatment allocation and study numbers held securely and in a separate location from the study ... See full document

... previous study where 12 women with >5% uNK cells conceived and 6 subse- quently miscarried (50%) ...endome- trial biopsies (Figure 2). The current on-going pilot study can confirm the presumptions ... See full document

... the study ’ s Independent Data Monitoring and Ethics Committee (IDMEC), will be performed after an appropriate number of patients have reached the six-month follow-up, to con- firm the final sample ...The ... See full document

... retrospective study, for patients with severe thrombocytopenia, rhTPO could rap- idly increase PCs, reduce 28-day mortality, and there were no severe adverse events during rhTPO ...the study, which was a ... See full document

... the trial in keeping with current recommended ...in randomised controlled ...largest trial of over 500 women used "need for an additional uterotonic agent" as the primary out- come ... See full document

... Symptoms of insomnia are commonly comorbid with depression, particularly in older adults [1]. In this popu- lation, although advanced sleep phase can occur, insom- nia is the most commonly reported sleep disturbance; ... See full document

... the design of the FOCUS ...other randomised clin- ical trial has assessed the effect of both neurocognitive and social cognitive remediation in a UHR ...the trial allows the opportunity to ... See full document

... Background: Trauma such as hip fracture initiates a neurohumoral stress response that changes the balance between anabolism and catabolism resulting in muscle breakdown and reduced mobilisation. Various studies have ... See full document

... The trial will be conducted in compliance with the principles of the Declaration of Helsinki (1996), the principles of GCP and in accordance with all applicable regulatory requirements in ...The trial is ... See full document

... the trial, all clinics will have an attached data clerk responsible for collecting identifiers of all consenting attendees of the chronic disease clinic to allow their identification in the MRC/Wits Agincourt ... See full document

... The primary comparison groups will be composed of those randomised to carvedilol versus those randomised to variceal band ligation. All analyses will be based on the intention-to-treat principle, that is, ... See full document

... hort study, which showed that continuous intravenous infusion of sedatives was associated with significantly lon- ger mechanical ventilation, increased length of stay in the ICU and in hospital, compared with ... See full document

... respond very rapidly and need only a few treatments, others require prolonged courses. In addition it is not uncommon for individual treatments in a course to be missed due to patient or timetabling factors. Unlike drug ... See full document

... The study is a cluster randomised trial to assess the feasibility of conducting an adequately powered, randomised controlled trial of clinically assisted hydration in patients ... See full document

... the study has concluded and all management beyond that time is according to the standard management policies of the treating trauma ...The trial design is deliberately pragmatic with no attempt to ... See full document

... The design of the trial is unusual since there are few psychosocial intervention studies that merit a factorial design; compare individual, group, and combined inter- ventions; and undertake a ... See full document

... mised controlled trial of antenatal screening and treat- ment for bacterial vaginosis, candidiasis and/or trichomoniasis in early pregnancy (15-19 weeks gesta- tion) among over 4 000 asymptomatic pregnant ... See full document

... Patients were followed for 6 weeks after randomisation. Patients completed a daily Visual Ana- logue Scale (VAS) score assessing breathlessness for a week prior to randomisation until the end of trial follow-up. ... See full document