[PDF] Top 20 Detection of human herpesviruses in the cerebrospinal fluid from patients diagnosed with or suspected of having progressive multifocal leukoencephalopathy
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Detection of human herpesviruses in the cerebrospinal fluid from patients diagnosed with or suspected of having progressive multifocal leukoencephalopathy
... specimens from patients suspected of having but not diagnosed with ...these patients were sus- pected of having ...the patients that were found to be positive for ... See full document
7
A loop mediated isothermal amplification assay for the detection and quantification of JC polyomavirus in cerebrospinal fluid: a diagnostic and clinical management tool and technique for progressive multifocal leukoencephalopathy
... JCV from latency in immunosuppressed patients, including hematopoietic stem cell transplant recipients, those with human immunodeficiency virus (HIV) infection, those with hematologic malignancies, ... See full document
11
Improving detection of JC virus by ultrafiltration of cerebrospinal fluid before polymerase chain reaction for the diagnosis of progressive multifocal leukoencephalopathy
... Given the size of viral particles, ultrafiltration mem- branes with large molecular cut-offs (e.g., 100 kDa) should be appropriate. However, in preliminary experi- ments, CSF specimens were too rapidly concentrated to a ... See full document
9
JC Virus-Specific Immune Responses in Human Immunodeficiency Virus Type 1 Patients with Progressive Multifocal Leukoencephalopathy
... Progressive multifocal leukoencephalopathy (PML) is a frequently fatal disease caused by uncontrolled polyomavirus JC (JCV) in severely immunodeficient ...with human immunodeficiency virus RNA ... See full document
8
HIV-associated neurologic disease incidence changes:Multicenter AIDS Cohort Study, 1990–1998
... toxoplasmosis, progressive multifocal leukoencephalopathy, and CNS lymphoma from January 1990 to December 1998 in the Multicenter AIDS Cohort ... See full document
5
Natalizumab-Related Progressive Multifocal Leukoencephalopathy-Immune Reconstitution Inflammatory Syndrome: a Case Report Highlighting Clinical and MRI Features
... exposure. Patients develop symptoms approximately 17–25 months after treatment ...MS patients treated with natalizumab is about 3–4/1000 ...in patients who have previously received immunosuppressive ... See full document
5
Vol 28, No 3 (2015)
... 21 patients with HIV Discussão: Os resultados do nosso estudo são concordantes com os dados previamente publicados relativamente à leucoencefa- lopatia multifocal progressiva, evidenciando a sua associação ... See full document
12
Rapid and Sensitive RT QuIC Detection of Human Creutzfeldt Jakob Disease Using Cerebrospinal Fluid
... assessment from all negative-control samples plus 10 standard ...values from replicate wells was higher than a predetermined threshold and at least two out of four replicate wells crossed that threshold ... See full document
7
Progressive multifocal leukoencephalopathy in a patient without apparent immunosuppression
... in patients with AIDS,[15] and a correlation with active antiretroviral treatment has been ...or progressive infec- tion may have led to the dissemination of the virus in the subarachnoid ... See full document
5
JC Virus Latency in the Brain and Extraneural Organs of Patients with and without Progressive Multifocal Leukoencephalopathy
... RR from all groups contained multiple types and mutations, which further support isolation and amplification of real physiological samples and not labo- ratory ...novel detection of the I-S, II-S, and I-R ... See full document
10
What is the risk of progressive multifocal leukoencephalopathy in patients with ulcerative colitis or Crohn’s Disease treated with vedolizumab?
... demonstrated only through a randomized, placebo-controlled clinical trial, with PML development as the primary outcome measure and with sufficient power to demonstrate equivalence between vedolizumab-treated ... See full document
32
Eight Plex PCR and Liquid Array Detection of Bacterial and Viral Pathogens in Cerebrospinal Fluid from Patients with Suspected Meningitis
... Gold standard definitions may cause false low specificities in cases in which a newly developed test is more sensitive than the test(s) used for the gold standard definition. In this study, we defined the gold standard ... See full document
6
Angiographic Abnormalities in Progressive Multifocal Leukoencephalopathy: An Explanation Based on Neuropathologic Findings
... other patients, suggest- ing a distinct relationship between the unique mi- crovascular inflammatory changes found in this le- sion and its contrast-enhancing characteristics on MR ... See full document
8
Multivariate proteomic analysis of the cerebrospinal fluid of patients with peripheral neuropathic pain and healthy controls – a hypothesis-generating pilot study
... The results from this hypothesis-generating pilot study have to be confirmed in larger, hypothesis-driven studies with age-matched controls. Nevertheless, the present report indicates a future possibility that a ... See full document
13
A case of developing progressive multifocal leukoencephalopathy while using rituximab and mycophenolate mofetil in refractory systemic lupus erythematosus
... HIV-positive patients, all of whom were taking highly active antiretroviral therapy (HAART), and three HIV-negative patients who had either cancer or systemic rheumatic ... See full document
5
Progressive Multifocal Leukoencephalopathy—A Case Report in an Immunocompetent Patient
... and progressive clinical and neurological worsening was observed and one month after the diagnosis the patient was aphasic and without the ability to have an autonomous ... See full document
7
Incidence, clinical presentation, and outcome of HIV-1-associated cryptococcal meningitis during the highly active antiretroviral therapy era: a nationwide cohort study
... study, they found that long-term survival after CM improved significantly with the use of HAART. Our study shows that most survivors recovered with only few neurological complications. This emphasizes the importance of ... See full document
8
Genotyping of JC Virus in Clinical Samples in North Eastern Iran
... The genome of the polyomaviruses shows a large number of sequence variations not only between JCV and BKV, but also in a variety of JCV sub-types (26). According to the previous studies, genotypes 1 and 4 are predominant ... See full document
7
Progressive multifocal leukoencephalitis in a patient with sarcoidosis on hydroxychloroquine with negative cerebrospinal fluid testing for the John Cunningham virus
... Due to his continued decline, PML was considered as an alternative to neuro-sarcoidosis and stereotactic brain biopsy was performed. Pathology revealed extensive gliosis, abundant lipid-laden macrophages, and large ... See full document
7
<p>Progressive Multifocal Leukoencephalopathy: Current Insights</p>
... NTZ-treated patients is 4.08 per 1000 patients (95% CI ...1000 patients). The duration of NTZ dosing prior to PML diagnosis ranged from 8 to 148 doses, and the mean duration of NTZ dosing at ... See full document
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