[PDF] Top 20 Detection of ErbB2: Nanotechnological solutions for clinical diagnostics

... for ErbB2-positive cancers. Additionally, the soluble cleaved form of ErbB2 protein (sErbB2), found in blood, has been shown to be a valuable marker for tumour diagnosis in ErbB2-positive breast ... See full document

... late-stage clinical trials, validate the feasibility of research in the field of nanotechnology and ...tumor detection, therapy, and monitoring mechanisms into one ...cancer detection and treatment ... See full document

... pathogen detection are available, their use often requires a significant degree of bioinformatic expertise that is typically not available in clinical ...actionable diagnostics, appropriate software ... See full document

... techniques. Nanotechnological innovations provide scientists and researchers with the new hope for progress in this direction through the advent of nanodiagnostics and its rapid ...of nanotechnological ... See full document

... fault detection and diagnostics methodology for three-phase separators based on Bayesian Belief Networks (BBN) is presented in this ...fault detection and diagnostics model was able to detect ... See full document

... in ErbB2 activation and initiation of ErbB2-mediated ...of ErbB2 and nucleolin leads to increased activation of the former and its downstream signaling through physical interaction between these two ... See full document

... detection of distant metastasis in NSCLC patients at initial staging. Articles were identified with a search of the MED- LINE and Embase databases through October 29, 2017. We used a search algorithm that was ... See full document

... molecular diagnostics, but all diagnostic meth- ods, including NAAT, sooner or later reach a test-specific limit of ...of detection would require venous blood samples and white blood cell depletion ...Thus, ... See full document

... complex clinical pathogenesis of AD, its classification is equally ...the clinical studies till date have focused over the familial AD but sporadic AD, of late, has become an intense topic of debate because ... See full document

... Enzymatic generation of reducing agent has been applied for DNA determination. This ap- proach deals with hybridization of target DNA with one immobilized on the electrode surface and subsequent hybridization with ... See full document

... The laboratory diagnostics in Poland has a long history. All the times, even in communistic era, it follows the world standards. Systematic significant increase of number of offered and ordered laboratory tests ... See full document

... of ERBB2-amplified tumors and may have implications in future clinical ...practice. ERBB2-amplified tumors have been treated with the monoclonal antibody trastuzumab ...of ERBB2 amplification ... See full document

... A treatment algorithm that might help in the management of these patients with ambivalent cases is postulated (Fig. 1). When there is a suspicion of necrotizing fasci- itis, skin lesions are marked, blood cultures are ... See full document

... whether ErbB2 was also required for cardiomyocyte migration in addition to its role in regulating cardiomyocyte ...of erbb2 mutant cardiomyocytes in wild-type ventricles by performing cell transplantation ... See full document

...  The societal implications of nanotechnology are the potential benefits and challenges that the introduction of novel nanotechnological devices and materials may hold for society and[r] ... See full document

... An alternative immunological method of brucellosis diagnostics, which is able to solve the above mentioned problems, is the detection of antibodies to Brucella species-specific proteins [r] ... See full document

... PSA has been a good reference to compare with other bioassays that have a measured PSA level. Using PSA detec- tion as the proof of principle for their developed bioassays will not be as advantageous as before. The ... See full document

... Moreover, through the manipulation of the characteristics of polymers, release of drug from nanostructures can be controlled to achieve the desired therapeutic concentration for the desi[r] ... See full document

... For the eleven Y772_A775dup patients, eight patients finally achieved PD, with a median PFS of 3 months. The other three patients were still under afatinib treatment, with two achieving PR and one with SD. Two patients ... See full document

... The construction industry should be considered as one of the strategic sectors where nanotechnology can be applied. Ensuring the university-industry cooperation will increase the possibilities of technology transfer. ... See full document