The similarity in the pH-dependencies and the KIEs of the ED286 and RK481 mutant CytcOs suggests that residues E286 and R481 are mechanistically linked, which is consistent with

Combined DFT and electrostatics study of the proton pumping mechanism in cytochrome c oxidase

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In the second case (case (ii)) where transfer of the substrate proton to the catalytic site is linked to a structural change, proton transfer to the pump site must be much faster

Rhodobacter sphaeroides functions as a proton pump much like the major enzymes of the heme- copper oxidase family.. In similar experiments with succinate as

Table 3 shows the recovery process in Indonesia classified by 14 kinds of urban infrastructure indicators such as department of housing (temporary housing and

In most com- puter simulations in the past, only subunit I was used (in very few cases subunit II was included) due to the reduced computational cost. However, it is believed

We focus on the dynamics and the free energy profiles of the excess proton and the surrounding protein environment near the active sites, and in particular, how the proton

Upon reduction of heme a, a proton is transferred, through the assistance of water molecules, from this residue to a proton-loading site (PLS) or “pump-site”, which is known

[ISWC09a] Daniel Gruhl, Meenakshi Nagarajan, Jan Pieper, Christine Robson, Amit Sheth, Context and Domain Knowledge Enhanced Entity Spotting in Informal Text, The

Upon ET, the first proton (fast reaction) is transferred to the PLS (His291), while subsequent transfer of the second ‘‘chemical’’ proton to the binuclear center (slow reaction)

This pH-independent rate would be observed because in this case the reaction rate is only determined by proton transfer from Glu286 to the catalytic site [39] and Glu286 is

We use comparative genomics, site-directed mutagenesis, and redox kinetics to demonstrate that the B-family of oxygen reductases utilize only one proton input channel, structurally

preliminary review aimed at looking at the need to conduct further studies on the implementation of thematic teaching and to determine the focus of the research. This

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The correct answer is d. Oftentimes people feel less shy online because they are not interacting with others face to face. What are some risks and some benefits to presenting

tetrahalidocadmate anions lie between the chains to maximize the electrostatic interactions and are connected with the organic cations via N—H Cl and C—H Cl(I) hydrogen

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