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[PDF] Top 20 Discrimination of Subtype B and Non Subtype B Strains of Human Immunodeficiency Virus Type 1 by Serotyping: Correlation with Genotyping

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Discrimination of Subtype B and Non Subtype B Strains of Human Immunodeficiency Virus Type 1 by Serotyping: Correlation with Genotyping

Discrimination of Subtype B and Non Subtype B Strains of Human Immunodeficiency Virus Type 1 by Serotyping: Correlation with Genotyping

... atypical subtype B GPGR V3 crown motif in the HIV sequences from all three specimens wrongly serotyped as subtype B concurs with the results of Sherefa et ...infecting virus. The ... See full document

5

Performance of Applied Biosystems ViroSeq HIV 1 Genotyping System for Sequence Based Analysis of Non Subtype B Human Immunodeficiency Virus Type 1 from Uganda

Performance of Applied Biosystems ViroSeq HIV 1 Genotyping System for Sequence Based Analysis of Non Subtype B Human Immunodeficiency Virus Type 1 from Uganda

... HIV-1 Genotyping System is a commercially available, integrated system for sequence-based analysis of drug resistance mutations in human immunodeficiency virus type 1 ... See full document

5

Human Immunodeficiency Virus Type 1 Subtype B Ancestral Envelope Protein Is Functional and Elicits Neutralizing Antibodies in Rabbits Similar to Those Elicited by a Circulating Subtype B Envelope

Human Immunodeficiency Virus Type 1 Subtype B Ancestral Envelope Protein Is Functional and Elicits Neutralizing Antibodies in Rabbits Similar to Those Elicited by a Circulating Subtype B Envelope

... HIV-1 subtype(s) in the targeted population (16, 18, 24, ...viable virus and thus produces antigens likely to adopt “native” ...other non- epidemiologically linked strains likely to be ... See full document

11

Extensive Diversification of Human Immunodeficiency Virus Type 1 Subtype B Strains during Dual Infection of a Chimpanzee That Progressed to AIDS

Extensive Diversification of Human Immunodeficiency Virus Type 1 Subtype B Strains during Dual Infection of a Chimpanzee That Progressed to AIDS

... of virus evolution in HIV-1-infected humans have concluded that dis- ease progression is associated with more extensive genetic di- versity (55, 65, 67), others have shown either that diversity correlates ... See full document

13

Simian-Human Immunodeficiency Virus Containing a Human Immunodeficiency Virus Type 1 Subtype-E Envelope Gene: Persistent Infection, CD4+ T-Cell Depletion, and Mucosal Membrane Transmission in Macaques

Simian-Human Immunodeficiency Virus Containing a Human Immunodeficiency Virus Type 1 Subtype-E Envelope Gene: Persistent Infection, CD4+ T-Cell Depletion, and Mucosal Membrane Transmission in Macaques

... of human immunodeficiency virus type 1 (HIV-1) determines several viral properties ...on subtype-B viral strains, prevalent in North America and ...of ... See full document

10

A Comprehensive Panel of Near-Full-Length Clones and Reference Sequences for Non-Subtype B Isolates of Human Immunodeficiency Virus Type 1

A Comprehensive Panel of Near-Full-Length Clones and Reference Sequences for Non-Subtype B Isolates of Human Immunodeficiency Virus Type 1

... eight strains in regions outside gag and env, we performed pairwise sequence comparisons with available full-length sequences from the ...(subtype B); C2220 (subtype C); ELI, NDK, and Z2Z6 ... See full document

19

Plasma RNA Viral Load in Human Immunodeficiency Virus Type 2 Subtype A and Subtype B Infections

Plasma RNA Viral Load in Human Immunodeficiency Virus Type 2 Subtype A and Subtype B Infections

... Human immunodeficiency virus type 2 (HIV-2) is much less pathogenic than HIV-1, and HIV-2 infection is associated with plasma viral loads significantly lower than those found in ... See full document

6

Performance Characteristics of Human Immunodeficiency Virus Type 1 (HIV 1) Genotyping Systems in Sequence Based Analysis of Subtypes Other than HIV 1 Subtype B

Performance Characteristics of Human Immunodeficiency Virus Type 1 (HIV 1) Genotyping Systems in Sequence Based Analysis of Subtypes Other than HIV 1 Subtype B

... HIV-1 genotyping system. The ViroSeq HIV-1 genotyping system generated sufficient ampli- con for all subtypes tested and delivered sequence data on all of the panel ...HIV-1 ... See full document

6

Failure of a human immunodeficiency virus type 1 (HIV-1) subtype B-derived vaccine to prevent infection of chimpanzees by an HIV-1 subtype E strain.

Failure of a human immunodeficiency virus type 1 (HIV-1) subtype B-derived vaccine to prevent infection of chimpanzees by an HIV-1 subtype E strain.

... between subtype B and E viruses was also observed when pooled serum samples selected for high neutralization activity against multiple ho- mologous virus strains were tested reciprocally ... See full document

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High Frequencyof Non-B HumanImmunodeficiency VirusType 1 (HIV-1)SubtypeSpecific Mutationsat theProtease GeneamongTreatment-naiveHIV-1 InfectedIndividualsinJos,Nigeria

High Frequency of Non-B Human Immunodeficiency Virus Type 1 (HIV-1) Subtype Specific Mutations at the Protease Gene among Treatment-naive HIV-1 Infected Individuals in Jos, Nigeria

... genetic subtype determination and phylogenetic analyses, population-based genotyping was performed using the REGA subtyping tool version ...worldwide subtype references were obtained from the Los ... See full document

14

Testing Genotypic and Phenotypic Resistance in Human Immunodeficiency Virus Type 1 Isolates of Clade B and Other Clades from Children Failing Antiretroviral Therapy

Testing Genotypic and Phenotypic Resistance in Human Immunodeficiency Virus Type 1 Isolates of Clade B and Other Clades from Children Failing Antiretroviral Therapy

... between B and non-B subtype ...detect subtype differences only among secondary resistance mutations, such as in residues 10, 20, 36, 63, 71, and ...in non-B ...direct ... See full document

8

Genotyping of B and Non B Subtypes of Human Immunodeficiency Virus Type 1

Genotyping of B and Non B Subtypes of Human Immunodeficiency Virus Type 1

... Study population and specimens. Samples were tested from HIV-1-infected patients attending the HIV clinics of Guy’s and St. Thomas’ Hospital Trust in South London between August 2000 and April 2003. The ethnicity ... See full document

5

Genetic Diversity of Protease and Reverse Transcriptase Sequences in Non Subtype B Human Immunodeficiency Virus Type 1 Strains: Evidence of Many Minor Drug Resistance Mutations in Treatment Naive Patients

Genetic Diversity of Protease and Reverse Transcriptase Sequences in Non Subtype B Human Immunodeficiency Virus Type 1 Strains: Evidence of Many Minor Drug Resistance Mutations in Treatment Naive Patients

... the strains had two or more minor mutations associated with PI resistance; only ...of strains (mainly subtype B strains) had no minor ...the strains overall and in 95% of the ... See full document

7

Use of Sequence Data Generated in the Bayer TruGene Genotyping Assay To Recognize and Characterize Non Subtype B Human Immunodeficiency Virus Type 1 Strains

Use of Sequence Data Generated in the Bayer TruGene Genotyping Assay To Recognize and Characterize Non Subtype B Human Immunodeficiency Virus Type 1 Strains

... of subtype on therapeutic ...determine subtype using the genomic re- gion targeted by antiretroviral agents, and thus the sequence information generated by commercial HIV genotyping sys- tems, such ... See full document

9

Subtype-Specific Differences in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Connection Subdomain of CRF01_AE Are Associated with Higher Levels of Resistance to 3′-Azido-3′-Deoxythymidine

Subtype-Specific Differences in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Connection Subdomain of CRF01_AE Are Associated with Higher Levels of Resistance to 3′-Azido-3′-Deoxythymidine

... HIV-1 subtype A and a yet to be identified “subtype ...patient’s virus contained numerous substitutions in the RT polymerase (POL) domain in addition to a long insertion between amino acids 67 ... See full document

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Susceptibility of Recently Transmitted Subtype B Human Immunodeficiency Virus Type 1 Variants to Broadly Neutralizing Antibodies

Susceptibility of Recently Transmitted Subtype B Human Immunodeficiency Virus Type 1 Variants to Broadly Neutralizing Antibodies

... against human immunode- ficiency virus type 1 (HIV-1) are unable to induce humoral immune responses of sufficient breadth and potency to protect against infection (20, ... See full document

10

Replicative Capacity Differences of Thymidine Analog Resistance Mutations in Subtype B and C Human Immunodeficiency Virus Type 1

Replicative Capacity Differences of Thymidine Analog Resistance Mutations in Subtype B and C Human Immunodeficiency Virus Type 1

... ⫹ 1. For the com- parison between different mutants, the s ⫹ 1 value is used and graphed ...as 1 because there is no advantage or disadvantage to the ...than 1, and less fit viruses will have ... See full document

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Increased Mucosal Transmission but Not Enhanced Pathogenicity of the CCR5-Tropic, Simian AIDS-Inducing Simian/Human Immunodeficiency Virus SHIVSF162P3 Maps to Envelope gp120

Increased Mucosal Transmission but Not Enhanced Pathogenicity of the CCR5-Tropic, Simian AIDS-Inducing Simian/Human Immunodeficiency Virus SHIVSF162P3 Maps to Envelope gp120

... Cells. Human osteosarcoma cells expressing CD4 and either human or rhesus CCR5 (HOS.CD4.CCR5) were gifts from N. Landau (Salk Institute, La Jolla, Calif.) and were maintained in Dulbecco’s modified Eagle’s ... See full document

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Refined Identification of Neutralization-Resistant HIV-1 CRF02_AG Viruses

Refined Identification of Neutralization-Resistant HIV-1 CRF02_AG Viruses

... Cloned envelope constructs were obtained through the AIDS Research and Reference Reagent Program (ARRRP), Division of AIDS, NIAID, NIH, from D. Montefiori, F. Gao, C. Williamson, S. Abdool Karim, J. Overbaugh, B. ... See full document

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A Combination of Broadly Neutralizing HIV-1 Monoclonal Antibodies Targeting Distinct Epitopes Effectively Neutralizes Variants Found in Early Infection

A Combination of Broadly Neutralizing HIV-1 Monoclonal Antibodies Targeting Distinct Epitopes Effectively Neutralizes Variants Found in Early Infection

... Because the PG and PGT MAbs failed to neutralize a majority of variants, we investigated whether these variants lacked the PNGS required for neutralization by these MAbs (Fig. 1). In some cases, resistance to ... See full document

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