[PDF] Top 20 DNA Mediated Charge Transport in DNA Repair

DNA Mediated Charge Transport in DNA Repair

... own DNA and also harbor an abundance of reactive oxygen species as a result of their function in oxidative phosphorylation ...mitochondrial DNA have been found in a variety of tumors and are associated with ... See full document

261

DNA Mediated Charge Transport Signaling Within the Cell

... efficient repair by UvrC A model for how DNA repair proteins with 4Fe-4S clusters utilize DNA-mediated CT chemistry as a means of signaling has been proposed by our ...model, ... See full document

187

Fundamental mechanisms and biological applications of DNA mediated charge transport

... stack; DNA binding-proteins, intervening mismatches, and base lesions can serve to attenuate charge migration ...of DNA CT to stacking perturbations has led to its application in developing novel ... See full document

203

Investigations of DNA-Mediated Redox Signaling Between E.coli DNA Repair Pathways

... a DNA glycosylase that excises oxi- dized pyrimidines from DNA, functioning as part of the base excision repair (BER) pathway in order to maintain the integrity of the genome ...the repair of ... See full document

128

Expanding the Repertoire of DNA-Mediated Signaling in DNA Repair

... of DNA-mediated charge transfer for each of these individual mutants, each protein (~10 µ M) was incubated on a DNA-modified electrode, and cyclic voltammagrams (CVs) were taken every 3 ... See full document

209

Activation of Transcription from a Distance: Investigations on the Oxidation of SoxR by DNA Mediated Charge Transport

... this DNA. Thus, DNA-mediated CT can occur along a distance long enough to effect SoxR ...of DNA to act as an antenna for oxidative damage in the cell, as the precursor species, oxidative ... See full document

122

DNA-Mediated Charge Transport for Long-Range Sensing and Protein Detection

... and charge delocalization also help to explain why such severe attenuation of DNA CT is observed when the structure of the DNA π-stack is ...which charge could delocalize, dramatically ... See full document

219

Regulation of Wild Type and Mutant p53 through DNA mediated Charge Transport

... through DNA CT, we used liquid chromatography coupled to nanoelectrospray, tandem mass spectrometric analysis of the digested peptides that have undergone differential cysteine ... See full document

104

DNA-Mediated Hole and Electron Transport

... of DNA bases. Before being trapped as permanent guanine damage, charge can undergo many pathways, which inevitably convolute the concomitant CT ...of charge that ...a DNA intercalator, were ... See full document

223

Spectroscopic characterization of DNA-mediated charge transfer

... the DNA double helix 3 ...long-range charge transport was demonstrated 12 ...duplex DNA self-assembled monolayers on gold 14 ...to charge transfer in DNA 18 ...in DNA 24 ... See full document

18

DNA-mediated Charge Transport in a Biological Context: Cooperation among Metalloproteins to Find Lesions in the Genome

... that DNA-mediated CT can trigger MutY, we have examined yet another system that includes a metallo transcription factor, ...to DNA (44). Due to the shift seen upon binding to DNA, we ... See full document

291

Magnetic Field Effects and Biophysical Studies on DNA Charge Transport and Repair

... the DNA before and after incubation show that at CRY1ΔC repairs T□T similar to ecPL (Figure ...duplex DNA, each containing a TT dimer in the absence of an applied magnetic field, irradiation with blue light ... See full document

204

DNA Mediated Charge Transport Devices for Protein Detection

... in charge determined from the area of the reductive peak plotted as a function of time, the rate of signal decrease for both the high density and ultra low-density monolayers upon TBP binding is almost ... See full document

354

Investigating DNA-Mediated Charge Transport by Time-Resolved Spectroscopy

... for charge, the probe should interact strongly with the DNA base ...the DNA strand or within the relatively narrow major and minor grooves which run lengthwise along the sides of the DNA ...of ... See full document

232

Exploring DNA Mediated Charge Transport with Fast Radical Traps

... DNA charge transport (CT) chemistry has received considerable attention by scientific researchers over the past 15 years since the first provocative publication on long-range CT in a DNA ...of ... See full document

221

Electrochemical sensors based on DNA mediated charge transport chemistry

... To take nothing away from the science done in the Barton Labs, one of my favorite things about working for Jackie is that she attracts a wonderful group of people and I have truly enjoyed my experience in lab for that ... See full document

15

The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts

... Using 8-oxoG cleavage assays with purified proteins, we previously showed that various combinations of Cut repeats and the Cut homeodomain (CR1CR2, CR3HD and CR2CR3HD) are able to stimulate the glycosylase activity of ... See full document

14

Increased non-homologous end joining makes DNA-PK a promising target for therapeutic intervention in uveal melanoma

... NHEJ repair is not clear at this ...UM repair DNA damage with studies showing as the authors have, that Olaporib is not efficient alone on UM [40] and that PRKDC is upregulated, with NU7026 being an ... See full document

13

Repair of Topoisomerase-Mediated DNA Damage in Bacteriophage T4

... topoisomerase- mediated damage and I-TevI breaks share similar protein ...total DNA was digested with ...probes. Repair bands (RC, NC, and LC) are most visible in ... See full document

10

Studies on protein:protein interactions in mammalian DNA base-excision repair

... stable DNA occurred via reduction of the 2 -OH ribose, making DNA more adequately equipped to hold the genetic information in a more or less intact ...of DNA is mainly due to the higher stability of ... See full document

210