[PDF] Top 20 Dorsoventral Patterning of the Drosophila melanogaster Embryo by the Dorsal/NF-κB Signaling Pathway
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Dorsoventral Patterning of the Drosophila melanogaster Embryo by the Dorsal/NF-κB Signaling Pathway
... of Dorsal signaling have been well documented, less is known about the global gradient ...shuttles Dorsal to the ventral midline, where Toll signaling acts as a ...free Dorsal present ... See full document
172
Dorsal/NF-κB exhibits a Dorsal-to-Ventral Mobility Gradient in the Drosophila Embryo
... Developmental Biology is the life science sector that aims in understanding can a single give rise to a completely new individual with all the incredible anatomical features that we find in multi-cellular organisms. This ... See full document
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Dorsal Ventral Patterning and Gene Regulation in the Early Embryo of Drosophila melanogaster
... TGF-ß signaling may also regulate the ind expression domains, but whether or not this signaling pathway functions through the A- box element was not ...to dorsal regions of the embryo ... See full document
120
Adipose Derived Stem Cell Transplantation Inhibits Vascular Inflammatory Responses and Endothelial Dysfunction in Rats with Atherosclerosis
... 1:1000; NF-κB p65, 1:1000; p-NF-κB p65, 1:1000, Abcam, Cambridge, MA, USA; VEGF, 1:1000; IκBα, 1:1000, Cell Signaling Technology, Beverly, MA, USA; GAPDH, 1:1000, Sino Biologial, ... See full document
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Original Article GF109203X attenuates RANKL-induced osteoclastogenesis and suppresses osteolysis in a mouse model
... factor κB ligand (RANKL) is the only factor that can directly stimulate the formation and functional activation of ...the signaling path of RANKL-induced osteoclastogenesis is a promising prevention and ... See full document
9
Differential Effects of Drosophila Mastermind on Asymmetric Cell Fate Specification and Neuroblast Formation
... The neurogenic defect in an embryo in which MamN was undergoes a size reduction (Figure 1c) and further ectopically expressed between 2 and 6 hr of age. (i) Ectopic downregulation of expression of RP2-specific ... See full document
10
Lhx2 links the intrinsic and extrinsic factors that control optic cup formation
... of dorsoventral polarity of the OV, and regional patterning of the optic neuroepithelium into neural retina, retinal pigment epithelium (RPE) and optic ...in Drosophila (Pappu and Mardon, 2004; ... See full document
12
Quantitative Single-Embryo Profile of Drosophila Genome Activation and the Dorsal–Ventral Patterning Network
... TGF-b signaling pathway is one of the best-studied sig- naling pathways in Drosophila, and model organisms in gen- eral, and because the components are well known, presents an opportunity to observe ... See full document
16
G Protein Pathway Suppressor 1 Promotes Influenza Virus Polymerase Activity by Activating the NF κB Signaling Pathway
... GPS1, NF- B signaling, M2, and influenza virus polymerase ...of NF- B signaling via the expression of influenza virus ...on NF- B signaling pathway activation was ... See full document
15
Original Article miR-146a regulates inflammatory cytokines and reverses high-glucose- and high-insulin-induced insulin resistance in 3T3-L1 adipocytes by targeting Traf6 through the NF-κB signaling pathway
... (Figure 5A and 5B) but had no effect on their expression of miR-146a (Figure 5C) as com- pared with the transfection of NC-pcDNA3.0 into miR-146a mimic-transfected IR-3T3-L1 adipocytes. The results also showed that the ... See full document
9
Original Article Long noncoding RNA MALAT1 modulates sepsis-induced cardiac inflammation through the miR-150-5p/NF-κB axis
... as NF-κB1, IL-6, TNF-α, intercel- lular adhesion molecule-1, vascular cell adhe- sion molecule-1, and E-selectin, and promotes apoptosis in human umbilical vein endothelial ... See full document
9
Herbal formula Xian Fang Huo Ming Yin regulates differentiation of lymphocytes and production of pro inflammatory cytokines in collagen induced arthritis mice
... anti- NF-κB kinase inhibitor (IKK)α/β, anti-NF-κB p50, anti- glycoprotein (gp)-130, anti-JAK1 and anti-STAT3 rabbit anti-mouse monoclonal antibodies (CST, Boston, MA, USA), and were then ... See full document
13
TWEAK activation of the non-canonical NF- B signaling pathway differentially regulates melanoma and prostate cancer cell invasion
... glycerol, and 1% Triton X-100) supplemented with a protease inhibitor cocktail (Sigma-Aldrich) and two phosphatase inhibitor cocktails (Calbiochem). The protein concentration of each lysate was determined by BCA protein ... See full document
19
Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis
... of NF-κB and COX-2 expression in mouse intestine by western ...suppresses NF-κB-COX-2 pathway in mouse ...on NF-κB-mediated inflammatory response in intestinal epithelial ... See full document
13
The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinoma
... Whole cell lysates were prepared for immunoblotting as described previously [23–25]. Equal amounts of total pro- teins (30 μg) were subjected to SDS-PAGE, transferred onto nitrocellulose, and immunoblotted with specific ... See full document
12
Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling
... Cell Signaling Technology), anti-IκB-α (4812; Transduction Laboratories), anti-Stat3 (Transduction Laboratories), anti-phospho-Stat3 (9131; Cell Signaling Technology), anti-phoshpo-p65 (3036; Cell ... See full document
14
Original Article Differences in gene expression profiles and signaling pathways in rhabdomyolysis-induced acute kidney injury
... many signaling pathways are altered as a consequence of gene expres- sion ...the NF-κB signaling pathway played an important role in rhabdomyolysis- induced ...in NF-κB ... See full document
12
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways
... Fig. 4 Relative activation of NF-κB and Akt pathways and SLPI downregulation in HPV positive HNSCC. a, b The proportion of p65 expressed in the cell nucleus in HPV positive tissues was significantly higher ... See full document
19
Curcumin attenuates MSU crystal induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage
... crystals into footpads and ankle joints. The process induced a series of inflammatory responses, similar to those that occur in acute gouty arthritis [36]. In MSU-injected foot- pads and ankle joint, curcumin treatment ... See full document
15
Original Article Role of Toll-like receptor 2/NF-κB signaling pathway in the pathogenesis of allergic rhinitis
... activated NF- κB and induced the release of related Th cyto- ...and NF-κB between the different groups were com- pared to explore the impact of NF-κB expres- sion levels on the ... See full document
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