[PDF] Top 20 Dynamics and Heterogeneity of Gene Expression and Epigenetic Regulation at the Single-Cell Level
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Dynamics and Heterogeneity of Gene Expression and Epigenetic Regulation at the Single-Cell Level
... a cell can either stay at its current state or switch to the other state with specified ...each cell a corresponding series of underlying states that has the maximum ...a cell that transiently ... See full document
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Heterogeneity of Single Cell Cytokine Gene Expression in Clonal T Cell Populations
... B7 costimulation markedly increased the frequency and the level of IL-2 mRNA expression in individual positive cells in the Thl and Th0 populations, with less effect on the r[r] ... See full document
12
Determining Physical Mechanisms of Gene Expression Regulation from Single Cell Gene Expression Data
... to cell-to-cell ...this heterogeneity with high throughput single cell gene expres- sion assays (single cell qPCR and ...generate gene expression ... See full document
29
Genetic and Epigenetic Regulation of Human lincRNA Gene Expression
... lincRNA gene expression by using the GenCord collection 22,25 of three cell-types (primary fibroblast cells, immortalized lympho- blastoid cell lines, and primary T cells) from 195 unrelated ... See full document
12
Epigenetic Regulation of Cytokine Gene Expression in T Lymphocytes
... Epigenetic regulation of IFN-γγ in Th1 differentiation In naïve T cells, most of CpG dinucleotides at regulatory elements are ...similar level of DNA methylation to that of naïve T cells, but some of ... See full document
9
Combined single cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity
... of single-cell data also affect the accuracy of the estimated splicing ratios per cassette ...in single-cell RNA-seq data can have a strong impact on the fit of the cell or gene ... See full document
14
Temporal dynamics and transcriptional control using single cell gene expression analysis
... temporal dynamics of a single-cell transcriptional network of 45 transcription factors in THP-1 human myeloid monocytic leukemia cells undergoing differentiation to ...temporal regulation of ... See full document
12
Errors during Gene Expression: Single Cell Heterogeneity, Stress Resistance, and Microbe Host Interactions
... ABSTRACT Gene expression has been considered a highly accurate process, and deviation from such fidelity has been shown previously to be detrimental for the ...of gene expression is indeed ... See full document
9
Beyond comparisons of means: understanding changes in gene expression at the single cell level
... differential expression tools are limited to detecting changes in overall expression, and fail to uncover the rich information provided by single-cell level data ...in ... See full document
14
Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development
... detailed gene expression data in humans there- fore hampers a thorough understanding of human kidney development and the possible developmental origin of kidney ...a single-cell transcrip- ... See full document
31
Deciphering the Gene Expression Control in Epigenetic, Post-transcriptional and Translational Regulation
... the single- base level has not been ...the epigenetic reprogramming and regulation that occurs during normal, bovine embryonic development in vivo, and to providing insight into the ... See full document
82
Single-Cell Analysis Reveals Distinct Gene Expression and Heterogeneity in Male and Female Plasmodium falciparum Gametocytes
... gender-specific expression of some genes is still debated ...gender-specific expression may result from reliance on population analyses of mixed gametocytes that include multiple differentiation stages and ... See full document
18
The Epigenetic Regulation of Blinatumomab Gene Expression: Tumor Cell-dependent T cell Response against Lymphoma Cells and Cytotoxic Activity
... for gene therapy (3, 4) and transgenic research (2, ...the gene after integration (7) whereas phiC31 integrase can catalyze unidirectional and irreversible recombination between attB and pseudo attP sites ... See full document
12
Epigenetic regulation of S100 protein expression
... their expression is by any means synchronized either in a cell-specific or develop- mental ...given cell type, a certain S100 protein may be abundant while the one encoded by a neighboring ... See full document
7
G-Quadruplex Dynamics Contribute To Regulation Of Mitochondrial Gene Expression
... a cell-free system with isolated ...the cell sensitivity to RHPS4, exacerbating the mitochondrial respiratory defects, but the molecular alterations caused by RHPS4 remains the subject of ...higher ... See full document
19
Epigenetic regulation of gene expression in osteoarthritis
... SOX9 expression in ...SOX9 expression in advanced hip OA chondrocytes is mediated by DNA methylation and histone modification, including histone methylation and ...SOX9 expression in human ... See full document
7
Epigenetic Regulation of Gene Expression in Keratinocytes
... regulated gene repositioning might be explained by the necessity for selected genes to reach a permissive nuclear environment required for maintenance or co-regulation of their expression (Lanctot et ... See full document
17
Characterizing heterogeneity in leukemic cells using single cell gene expression analysis
... Importantly, Meis1, a rate-limiting factor for the de- velopment of AF9-MLL induced AML [43], is highly expressed only in the leukemic cells. We also found important differences between the two subtypes of leu- kemic ... See full document
13
Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia
... with gene expression (from 5% and 2% to 9% and 8%, ...and gene expression were most frequently found in CpG open sea enhancer regions within the gene body, while those with a ... See full document
13
Epigenetic and Expression Regulation -.ppt
... in Epigenetic mechanisms can regulate genes involved in differentiation, cell cycle, and cell survival differentiation, cell cycle, and cell survival Deregulation of epigenetic ... See full document
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