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18 results with keyword: 'dynamics stem cells niche progeny hair follicle'

Dynamics between Stem Cells, Niche, and Progeny in the Hair Follicle

Given that from catagen to telogen, the initial bulge showed no major change in size or cell number (Figure S2E), our collec- tive evidence favored ORS GFP+ as the major source of

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2021
Compartmentalized organization: a common and required feature of stem cell niches?

( A )  A schematic of the hair follicle stem cell niche, which resides in the lower part of the follicle and comprises epithelial cells (the bulge and the hair germ) and

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2020
What does the concept of the stem cell niche really mean today?

One of their important niche components is the inner layer of the bulge, marked by K6 staining (in red) and composed of differentiated hair follicle stem cell progeny that

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2020
Bulge Region as a Putative Hair Follicle Stem Cells Niche: A Brief Review

isolated Nestin positive cells from mouse hair follicle bulge, then cultured these cells in vitro and subjected to classIII beta-tubulin +ve neuronal type cells, then cells

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2020
Review Paper: Application of Hair Follicle Bulge Stem Cells in Wound Healing

Therapeutic capacity of the most stem cell populations in - cluding Embryonic Stem Cells (ESCs), induced Pluripotent Stem Cells (iPSCs), hair follicle bulge stem cells and adult

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2020
CELL-INTRINSIC MECHANISMS GOVERNING STEM CELL QUIESCENCE AND REGULATING CANCER PROGRESSION IN MAMMALIAN SKIN

Morphogenesis and renewal of hair follicles from adult multipotent stem cells.. Paracrine TGF-b Signaling Counterbalances BMP-Mediated Repressionin Hair Follicle Stem

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2021
Gene expression profiling gets to the root of human hair follicle stem cells

Hair follicle stem cells sustain growth and cycling of the hair follicle and are located in the permanent portion of the follicle known as the bulge.. In this issue of the JCI

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2020
The role of extracellular vesicles in cutaneous remodeling and hair follicle dynamics

Photoactivation of ROS Production in Situ Transiently Activates Cell Proliferation in Mouse Skin and in the Hair Follicle Stem Cell Niche Promoting Hair Growth and Wound

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2021
Activated Hair Follicle Stem Cells and Wnt/β-catenin Signaling Involve in Pathnogenesis of Sebaceous Neoplasms

Sebaceous glands (SGs) undergo cyclic renewal independent of hair follicle stem cells (HFSCs) activation while HFSCs have the potential to differentiate into sebaceous gland

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2022
Specification And Function Of Early Hair Follicle Stem Cells

Preliminary data on wound healing in the interfollicular epidermis and colony formation activity suggest that early SCs may be more potent that adult SCs, but

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2021
Modulation of Wnt/β-catenin signaling affects the directional differentiation of hair follicle stem cells

Figure 8: Effect of different keratinocyte growth factor (KGF) concentrations on hair follicle stem cells proliferation.. Cells were assessed 3 days after

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2020
Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging

It remains to be seen why various lamin A mutations have such diverse effects on mesenchymal stem cells and hair follicle stem cells, whether the differentiation capacity of

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2021
Vitamin B12 Activates the Wnt Pathway in Human Hair Follicle Cells by Induction of beta Catenin and Inhibition of Glycogensynthase Kinase 3 Transcription

As a result of wnt-pathway activation in hair follicle cells, cell proliferation is increased in different compartments of the hair follicle leading organogenesis in hair

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2020
London Local Enterprise Partnership: Register of Members Interests

I, Jane Sherwood, as a Board Member/Co-opted Member of the Royal Docks Enterprise Zone Programme Board, declare that I have the following disclosable pecuniary and/or

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2022
Dissecting the bulge in hair regeneration

The adult hair follicle houses stem cells that govern the cyclical growth and differentiation of multiple cell types that collectively produce a pigmented hair.. Recent studies

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2020
Immunohistochemical study of hair follicle stem cells in regenerated hair follicles induced by Wnt10b

To determine whether Wnt10b induces activation of HFSCs in the Wnt10b-induced anagen hair follicles, we evaluated the expression patterns of several HFSC markers.. CD34

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2022
Pten loss in Lgr5+ hair follicle stem cells promotes SCC development

Methods : We established experiments with wildtype and Lgr5-CreER; Pten flox/flox mice, and used DMBA/TPA two-stage skin carcinogenesis model to explore the effect of Pten

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2020
HAIR FOLLICLE STEM CELLS IN THE PATHOGENESIS OF PRIMARY CICATRICIAL ALOPECIA

In discoid lupus erythematosus, another type of cicatricial alopecia, CK15 expression is weak or absent in the bulge area, with severe inflammation further

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2020

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