[PDF] Top 20 E. B. Lewis and the Bithorax Complex: Part I
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E. B. Lewis and the Bithorax Complex: Part I
... by Lewis in the early ...to Lewis that cases of pseudoallelism would al- and Ubx/bxd animals resemble bxd ...to Lewis that the bx, Ubx, and Of course, these models were developed before there bxd ... See full document
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E. B. Lewis and the Bithorax Complex: Part II. From cis-trans Test to the Genetic Control of Development
... similarities, Lewis adopted the op- early 1960s that Lewis developed or reinforced three eron as an alternate framework for interpreting the key concepts that were extraordinarily influential in set- ... See full document
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The Border Between the Ultrabithorax and abdominal-A Regulatory Domains in the Drosophila Bithorax Complex
... The distal bxd domain includes the coding region of the sugar transporter homolog, Glut3, which was first identified by examination of the BX-C sequence (Martin et al. 1995). Glut3 is the only “foreign” gene in the ... See full document
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Modeling the regulation of the bithorax complex in Drosophila melanogaster: the phenotypic effects of Ubx, abd A and Abd B heterozygotic larvae, and a homozygous Ubx abd A hybrid gene
... Inl I De, Bioi 13 455 466 (1989) 455 Original A rtir/r Modeling the regulation of the bithorax complex in Drosophila melanogaster the phenotypic effects of Ubx , abd A and Abd B heterozygotic larvae,[.] ... See full document
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Different Evolutionary Strategies To Conserve Chromatin Boundary Function in the Bithorax Complex
... Drosophila Bithorax complex boundary element called Fab-7, which is required for the proper parasegment specific expression of the homeotic Abd-B ... See full document
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Distinct Roles of Chromatin Insulator Proteins in Control of the Drosophila Bithorax Complex
... the bithorax complex are contained within a broad topological domain that spans 330 kb from the 39 end of the Ubx gene to a region 10 kb upstream of the Abd-B gene (Sexton et ...the bithorax ... See full document
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Architectural protein Pita cooperates with dCTCF in organization of functional boundaries in Bithorax complex
... Boundaries in the Bithorax complex (BX-C) of Drosophila delimit autonomous regulatory domains that drive parasegment-specific expression of homeotic genes. BX-C boundaries have two crucial functions: they ... See full document
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Boundary swapping in the Drosophila Bithorax complex
... Drosophila Bithorax complex (BX-C) have properties similar to chromatin insulators, genetic substitution experiments have demonstrated that these elements do more than simply insulate adjacent ... See full document
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Enhancer traps in the Drosophila bithorax complex mark parasegmental domains.
... Competition of regulatory signals: Several enhancer trap lines carry regulatory DNA fragments from the bithorax complex within the P element, and these se- quences d[r] ... See full document
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Tumorous-head (tuh-1; tuh-3) modulates Abd-B bithorax-complex functions in Drosophila melanogaster.
... Penetrance of head defects varied between mutants (Table 2). A specific group of Abd-B mutants eliminated m function from PSlO through PS13. Yet, they did not suppress t[r] ... See full document
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Transvection in the Ultrabithorax domain of the bithorax complex of Drosophila melanogaster.
... is an RNA polymerase (shown shortly after the initiation of tran- scription), the thin wavy line is RNA, the thick line is DNA, and the solid arrowheads are t[r] ... See full document
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Non genic transcription at the Drosophila bithorax complex – functional activity of the dark matter of the genome
... repressive complex is formed as PcG proteins (red shaded ellipses) bind to the PRE and silence transcrip- tion of Abd-B (Zink and Paro, 1995), a process in which the RNAi machinery is not involved (Grimaud ... See full document
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The bithorax complex: the first fifty years
... and Lewis, 1987) indicate that the pigmentation pattern of the bands resembles that normally found in the tergites of segments A5 and ...and Lewis, 1993) of the dorsal thoracic disc of T2, which gives rise ... See full document
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Cis and trans interactions between the iab regulatory regions and abdominal-A and abdominal-B in Drosophila melanogaster.
... ( 1992) , who found that a putative negative regulatory element in the bxd region of the bithorax complex can apparently exert its negative effect in trans independent[r] ... See full document
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Dissecting the regulatory landscape of the Abd B gene of the bithorax complex
... The three homeotic genes of the bithorax complex (BX-C), Ubx, abd-A and Abd-B control the identity of the posterior thorax and all abdominal segments. Large segment-specific cis-regulatory regions ... See full document
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The ABC of the BX C: the bithorax complex explained
... Throughout the 90 years of BX-C research, the BX-C has constantly provided the scientific world with exciting new findings. From the striking and conserved correlation between genomic position and segmental function ... See full document
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Noncoding RNAs of the Ultrabithorax Domain of the Drosophila Bithorax Complex
... cassette exchange (RMCE) (Bateman and Wu 2008) to al- low modifications across most of the bxd domain (Figure 4). A BAC had been constructed (O’Connor et al. 1989), cover- ing 45 kb of Drosophila genomic DNA, from within ... See full document
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Training and Evaluation of a Spoken Language Understanding System
... Training and Evaluation of a Spoken Language Understanding System Training and Evaluation of a Spoken Language Understanding System D e b o r a h A D a h l , L y n e t t e H i r s c h m a n , Lewis M[.] ... See full document
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Edward B. Lewis, 1918–2004
... liberal I first met Ed Lewis in 1980, as a biochemistry graduate use of dental X rays and ...and I gave the the risk of radiation-induced cancer from the ...and I engaged in a lively ... See full document
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ROOT N U M B E R SO F A B E L I A NV A R I E T I E SA N D REPRESENTATIONS O F T H E WE I L - D E L I G N EG R O U P
... Theorem 1.0.1. Let F be a number field, L a finite Galois extension of F , and τ an irreducible complex finite-dimensional representation of Gal(L/F ) with real- valued character. Let g be a fixed positive integer ... See full document
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